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Protein

Small nuclear ribonucleoprotein G

Gene

SNRPG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Core component of the small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoproteinUniRule annotationSAAS annotation, RNA-bindingUniRule annotation
Biological processmRNA processing, mRNA splicing

Names & Taxonomyi

Protein namesi
Recommended name:
Small nuclear ribonucleoprotein GUniRule annotation
Short name:
snRNP-GUniRule annotation
Gene namesi
Name:SNRPGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000143977.13
HGNCiHGNC:11163 SNRPG

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation, SpliceosomeUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143977

Expressioni

Gene expression databases

BgeeiENSG00000143977 Expressed in 91 organ(s), highest expression level in female gonad

Interactioni

Protein-protein interaction databases

IntActiQ49AN9, 1 interactor
Q49AN9, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60SmInterPro annotationAdd BLAST60

Sequence similaritiesi

Belongs to the snRNP Sm proteins family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1780 Eukaryota
ENOG41122Q1 LUCA
GeneTreeiENSGT00510000046985
HOGENOMiHOG000223546
HOVERGENiHBG000513

Family and domain databases

CDDicd01719 Sm_G, 1 hit
InterProiView protein in InterPro
IPR001163 LSM_dom_euk/arc
IPR010920 LSM_dom_sf
IPR034098 Sm_G
PfamiView protein in Pfam
PF01423 LSM, 1 hit
SMARTiView protein in SMART
SM00651 Sm, 1 hit
SUPFAMiSSF50182 SSF50182, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q49AN9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKKLSLKLN GGRHVQGILR GFDPFMNLVI DECVEMATSG QQNNIGMVVI
60
RGNSIIMLEA LERV
Length:64
Mass (Da):7,101
Last modified:September 13, 2005 - v1
Checksum:iC4CD50C001BE4D4D
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P62308RUXG_HUMAN
Small nuclear ribonucleoprotein G
SNRPG PBSCG
76Annotation score:
C9JVQ0C9JVQ0_HUMAN
Small nuclear ribonucleoprotein G
SNRPG
96Annotation score:
F5H013F5H013_HUMAN
Small nuclear ribonucleoprotein G
SNRPG
68Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079338 Genomic DNA No translation available.
BC035103 mRNA Translation: AAH35103.1
RefSeqiNP_001304097.1, NM_001317168.1
NP_001304098.1, NM_001317169.1
UniGeneiHs.465167
Hs.516076
Hs.631639
Hs.654528

Genome annotation databases

EnsembliENST00000438261; ENSP00000402194; ENSG00000143977
ENST00000449935; ENSP00000391403; ENSG00000143977
ENST00000482975; ENSP00000441332; ENSG00000143977
GeneIDi6637
UCSCiuc061kiu.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079338 Genomic DNA No translation available.
BC035103 mRNA Translation: AAH35103.1
RefSeqiNP_001304097.1, NM_001317168.1
NP_001304098.1, NM_001317169.1
UniGeneiHs.465167
Hs.516076
Hs.631639
Hs.654528

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ49AN9, 1 interactor
Q49AN9, 1 interactor

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000438261; ENSP00000402194; ENSG00000143977
ENST00000449935; ENSP00000391403; ENSG00000143977
ENST00000482975; ENSP00000441332; ENSG00000143977
GeneIDi6637
UCSCiuc061kiu.1 human

Organism-specific databases

CTDi6637
EuPathDBiHostDB:ENSG00000143977.13
HGNCiHGNC:11163 SNRPG
OpenTargetsiENSG00000143977
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1780 Eukaryota
ENOG41122Q1 LUCA
GeneTreeiENSGT00510000046985
HOGENOMiHOG000223546
HOVERGENiHBG000513

Miscellaneous databases

ChiTaRSiSNRPG human

Gene expression databases

BgeeiENSG00000143977 Expressed in 91 organ(s), highest expression level in female gonad

Family and domain databases

CDDicd01719 Sm_G, 1 hit
InterProiView protein in InterPro
IPR001163 LSM_dom_euk/arc
IPR010920 LSM_dom_sf
IPR034098 Sm_G
PfamiView protein in Pfam
PF01423 LSM, 1 hit
SMARTiView protein in SMART
SM00651 Sm, 1 hit
SUPFAMiSSF50182 SSF50182, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ49AN9_HUMAN
AccessioniPrimary (citable) accession number: Q49AN9
Secondary accession number(s): C9J303
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 7, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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