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Entry version 113 (07 Apr 2021)
Sequence version 2 (31 Oct 2006)
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Protein

Transcription termination factor 2, mitochondrial

Gene

MTERF2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds mitochondrial DNA and plays a role in the regulation of transcription of mitochondrial mRNA and rRNA species.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q49AM1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription termination factor 2, mitochondrial
Alternative name(s):
Mitochondrial transcription termination factor 2
Short name:
mTERF2
Mitochondrial transcription termination factor-like protein
Short name:
mTERF-like
Short name:
mTERFL1 Publication
mTERF domain-containing protein 3, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTERF2
Synonyms:MTERFD3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30779, MTERF2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616929, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q49AM1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000120832.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion, Mitochondrion nucleoid

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80298

Open Targets

More...
OpenTargetsi
ENSG00000120832

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671311

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q49AM1, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MTERF2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
118595440

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 35Mitochondrion1 PublicationAdd BLAST35
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025546436 – 385Transcription termination factor 2, mitochondrialAdd BLAST350

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q49AM1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q49AM1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q49AM1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q49AM1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q49AM1

PeptideAtlas

More...
PeptideAtlasi
Q49AM1

PRoteomics IDEntifications database

More...
PRIDEi
Q49AM1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
62055

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q49AM1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q49AM1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in skeletal muscle, heart, liver and pancreas.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000120832, Expressed in left lobe of thyroid gland and 215 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q49AM1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q49AM1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000120832, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
123214, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q49AM1, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000447651

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q49AM1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q49AM1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the mTERF family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1267, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063817

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_058644_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q49AM1

Identification of Orthologs from Complete Genome Data

More...
OMAi
WVLLEDE

Database of Orthologous Groups

More...
OrthoDBi
1103140at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q49AM1

TreeFam database of animal gene trees

More...
TreeFami
TF330821

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.70.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003690, MTERF
IPR038538, MTERF_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02536, mTERF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00733, Mterf, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q49AM1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLWKLLLRSQ SCRLCSFRKM RSPPKYRPFL ACFTYTTDKQ SSKENTRTVE
60 70 80 90 100
KLYKCSVDIR KIRRLKGWVL LEDETYVEEI ANILQELGAD ETAVASILER
110 120 130 140 150
CPEAIVCSPT AVNTQRKLWQ LVCKNEEELI KLIEQFPESF FTIKDQENQK
160 170 180 190 200
LNVQFFQELG LKNVVISRLL TAAPNVFHNP VEKNKQMVRI LQESYLDVGG
210 220 230 240 250
SEANMKVWLL KLLSQNPFIL LNSPTAIKET LEFLQEQGFT SFEILQLLSK
260 270 280 290 300
LKGFLFQLCP RSIQNSISFS KNAFKCTDHD LKQLVLKCPA LLYYSVPVLE
310 320 330 340 350
ERMQGLLREG ISIAQIRETP MVLELTPQIV QYRIRKLNSS GYRIKDGHLA
360 370 380
NLNGSKKEFE ANFGKIQAKK VRPLFNPVAP LNVEE
Length:385
Mass (Da):44,414
Last modified:October 31, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF6D948759681BBE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VSD8F8VSD8_HUMAN
Transcription termination factor 2,...
MTERF2
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VXH5F8VXH5_HUMAN
Transcription termination factor 2,...
MTERF2
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VSL4F8VSL4_HUMAN
Transcription termination factor 2,...
MTERF2
33Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti140F → S in BAD96278 (Ref. 3) Curated1
Sequence conflicti171T → A in AAH36066 (PubMed:16541075).Curated1
Sequence conflicti236E → G in BAB14834 (PubMed:14702039).Curated1
Sequence conflicti383V → A in BAD96278 (Ref. 3) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03411314L → V. Corresponds to variant dbSNP:rs34238336EnsemblClinVar.1
Natural variantiVAR_05378731A → V. Corresponds to variant dbSNP:rs35305400EnsemblClinVar.1
Natural variantiVAR_03411481A → G. Corresponds to variant dbSNP:rs35548605EnsemblClinVar.1
Natural variantiVAR_053788198V → I. Corresponds to variant dbSNP:rs1043157Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY008301 mRNA Translation: AAG22860.1
AK024124 mRNA Translation: BAB14834.1
AK222558 mRNA Translation: BAD96278.1
AL832827 mRNA Translation: CAI46173.1
AC007541 Genomic DNA No translation available.
BC025984 mRNA Translation: AAH25984.1
BC036066 mRNA Translation: AAH36066.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9111.1

NCBI Reference Sequences

More...
RefSeqi
NP_001028222.1, NM_001033050.2
NP_079474.2, NM_025198.4
XP_011537069.1, XM_011538767.2
XP_016875474.1, XM_017019985.1
XP_016875475.1, XM_017019986.1
XP_016875476.1, XM_017019987.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000240050; ENSP00000240050; ENSG00000120832
ENST00000392830; ENSP00000376575; ENSG00000120832
ENST00000552029; ENSP00000447651; ENSG00000120832

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80298

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80298

UCSC genome browser

More...
UCSCi
uc001tme.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY008301 mRNA Translation: AAG22860.1
AK024124 mRNA Translation: BAB14834.1
AK222558 mRNA Translation: BAD96278.1
AL832827 mRNA Translation: CAI46173.1
AC007541 Genomic DNA No translation available.
BC025984 mRNA Translation: AAH25984.1
BC036066 mRNA Translation: AAH36066.1
CCDSiCCDS9111.1
RefSeqiNP_001028222.1, NM_001033050.2
NP_079474.2, NM_025198.4
XP_011537069.1, XM_011538767.2
XP_016875474.1, XM_017019985.1
XP_016875475.1, XM_017019986.1
XP_016875476.1, XM_017019987.1

3D structure databases

SMRiQ49AM1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi123214, 7 interactors
IntActiQ49AM1, 7 interactors
STRINGi9606.ENSP00000447651

PTM databases

iPTMnetiQ49AM1
PhosphoSitePlusiQ49AM1

Genetic variation databases

BioMutaiMTERF2
DMDMi118595440

Proteomic databases

EPDiQ49AM1
jPOSTiQ49AM1
MassIVEiQ49AM1
MaxQBiQ49AM1
PaxDbiQ49AM1
PeptideAtlasiQ49AM1
PRIDEiQ49AM1
ProteomicsDBi62055

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1265, 73 antibodies

The DNASU plasmid repository

More...
DNASUi
80298

Genome annotation databases

EnsembliENST00000240050; ENSP00000240050; ENSG00000120832
ENST00000392830; ENSP00000376575; ENSG00000120832
ENST00000552029; ENSP00000447651; ENSG00000120832
GeneIDi80298
KEGGihsa:80298
UCSCiuc001tme.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80298
DisGeNETi80298

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTERF2
HGNCiHGNC:30779, MTERF2
HPAiENSG00000120832, Low tissue specificity
MIMi616929, gene
neXtProtiNX_Q49AM1
OpenTargetsiENSG00000120832
PharmGKBiPA142671311
VEuPathDBiHostDB:ENSG00000120832.9

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1267, Eukaryota
GeneTreeiENSGT00530000063817
HOGENOMiCLU_058644_0_0_1
InParanoidiQ49AM1
OMAiWVLLEDE
OrthoDBi1103140at2759
PhylomeDBiQ49AM1
TreeFamiTF330821

Enzyme and pathway databases

PathwayCommonsiQ49AM1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
80298, 8 hits in 988 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80298
PharosiQ49AM1, Tbio

Protein Ontology

More...
PROi
PR:Q49AM1
RNActiQ49AM1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000120832, Expressed in left lobe of thyroid gland and 215 other tissues
ExpressionAtlasiQ49AM1, baseline and differential
GenevisibleiQ49AM1, HS

Family and domain databases

Gene3Di1.25.70.10, 2 hits
InterProiView protein in InterPro
IPR003690, MTERF
IPR038538, MTERF_sf
PfamiView protein in Pfam
PF02536, mTERF, 1 hit
SMARTiView protein in SMART
SM00733, Mterf, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTEF2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q49AM1
Secondary accession number(s): Q53HM2, Q9H4L6, Q9H7Y9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: April 7, 2021
This is version 113 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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