Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 111 (11 Dec 2019)
Sequence version 3 (28 Mar 2018)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Uncharacterized protein C8orf34

Gene

C8orf34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

It is uncertain whether Met-1 or Met-87 is the initiator methionine.Curated

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C8orf34
Alternative name(s):
Protein VEST-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C8orf34
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000165084.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30905 C8orf34

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q49A92

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
116328

Open Targets

More...
OpenTargetsi
ENSG00000165084

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672353

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q49A92 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C8orf34

Domain mapping of disease mutations (DMDM)

More...
DMDMi
187470865

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003300391 – 538Uncharacterized protein C8orf34Add BLAST538

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q49A92

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q49A92

PeptideAtlas

More...
PeptideAtlasi
Q49A92

PRoteomics IDEntifications database

More...
PRIDEi
Q49A92

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
33789
62033 [Q49A92-2]
62034 [Q49A92-3]
62035 [Q49A92-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q49A92

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q49A92

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000165084 Expressed in 117 organ(s), highest expression level in oviduct epithelium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q49A92 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q49A92 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044420
HPA053065

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125497, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q49A92, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000427820

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q49A92 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFD0 Eukaryota
ENOG4111YR7 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005870

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000060121

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q49A92

Identification of Orthologs from Complete Genome Data

More...
OMAi
NQGRATY

Database of Orthologous Groups

More...
OrthoDBi
667565at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q49A92

TreeFam database of animal gene trees

More...
TreeFami
TF332826

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040687 DUF5586

The PANTHER Classification System

More...
PANTHERi
PTHR32000 PTHR32000, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17824 DUF5586, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q49A92-6) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSPLASELS ELAALRPGFR LSAPHARVAP RAATHARGRG RASHAGQPRL
60 70 80 90 100
RSSCPGPSPG KRRVVPSGGA QPRVLPALSS RSHLFPMASH PQTRIQAYLE
110 120 130 140 150
KNKIGPLFEE LMTKLITETP DQPIPFLIDH LQSKQGNRGQ LQRTLSGSAA
160 170 180 190 200
LWAESEKSES KGTRRDFRSY DKPWQLNAKK PKKSKSDLAV SNISPPSPDS
210 220 230 240 250
KSLPRSVEHP KWNWRTKPQS RDFDELNHIL QESKKLGKAL ENLSRSIAIS
260 270 280 290 300
DELDKETVTF NSSLLRPRVI GEWIGREEND ADPLAAEMLQ PPIPRSKNDQ
310 320 330 340 350
WESEDSGSSP AGSLKMEPKN KGLKQQQQQH KKLLAAMLSQ DSFESIHSPT
360 370 380 390 400
PSVTEEDIDN EDDAMELLED LNDLRMEGVT TLVPSGSKFN QGRPTYPAEP
410 420 430 440 450
QAKVTLNICS RCARLQGDNL EERTEESLPI LHSPDEKIPD SFDSLPGTEE
460 470 480 490 500
ALMEEGDEFE KASKLTGPGE ASSGVGHSLK NYMEEDESLK QLQVVHQPWI
510 520 530
LPSDTESEGV EAEQEKRSAD LLLCVPCSSC PTLVYSGL
Length:538
Mass (Da):59,434
Last modified:March 28, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i813DC01121888F68
GO
Isoform 2 (identifier: Q49A92-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-111: Missing.

Show »
Length:427
Mass (Da):47,593
Checksum:iA75B18021FA45BAB
GO
Isoform 3 (identifier: Q49A92-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-86: Missing.
     369-373: EDLND → GNFKN
     374-538: Missing.

Show »
Length:287
Mass (Da):32,460
Checksum:i47418322096C958D
GO
Isoform 4 (identifier: Q49A92-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-368: MSSPLASELS...DNEDDAMELL → MENGFTMCQTGRQHPVACGLHLSGGK
     517-538: RSADLLLCVPCSSCPTLVYSGL → HLLNQNLCGWDSEFCIFHTLASFLIYK

Show »
Length:201
Mass (Da):22,266
Checksum:iD5D282CF71B5F730
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RJD9E5RJD9_HUMAN
Uncharacterized protein C8orf34
C8orf34
206Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2P0CTR9A0A2P0CTR9_HUMAN
Uncharacterized protein C8orf34
C8orf34
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH41961 differs from that shown. Reason: Frameshift.Curated
The sequence AAH41961 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_042690161K → N in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_042691512A → T1 PublicationCorresponds to variant dbSNP:rs16935065Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0594731 – 368MSSPL…AMELL → MENGFTMCQTGRQHPVACGL HLSGGK in isoform 4. Add BLAST368
Alternative sequenceiVSP_0594741 – 111Missing in isoform 2. 1 PublicationAdd BLAST111
Alternative sequenceiVSP_0594751 – 86Missing in isoform 3. Add BLAST86
Alternative sequenceiVSP_059476369 – 373EDLND → GNFKN in isoform 3. 2 Publications5
Alternative sequenceiVSP_059477374 – 538Missing in isoform 3. Add BLAST165
Alternative sequenceiVSP_059478517 – 538RSADL…VYSGL → HLLNQNLCGWDSEFCIFHTL ASFLIYK in isoform 4. 1 PublicationAdd BLAST22

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB056652 mRNA Translation: BAB64433.1
AK094191 mRNA Translation: BAC04304.1
AK094650 mRNA Translation: BAC04395.1
AK291436 mRNA Translation: BAF84125.1
AL834454 mRNA Translation: CAD39114.2
AC011884 Genomic DNA No translation available.
AC067871 Genomic DNA No translation available.
AC083967 Genomic DNA No translation available.
AC090096 Genomic DNA No translation available.
KF458778 Genomic DNA No translation available.
KF458774 Genomic DNA No translation available.
CH471068 Genomic DNA Translation: EAW86947.1
CH471068 Genomic DNA Translation: EAW86949.1
BC041961 mRNA Translation: AAH41961.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6203.2 [Q49A92-6]

NCBI Reference Sequences

More...
RefSeqi
NP_443190.2, NM_052958.2 [Q49A92-6]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000325233; ENSP00000319532; ENSG00000165084 [Q49A92-4]
ENST00000337103; ENSP00000337174; ENSG00000165084 [Q49A92-2]
ENST00000348340; ENSP00000345255; ENSG00000165084 [Q49A92-3]
ENST00000518698; ENSP00000427820; ENSG00000165084 [Q49A92-6]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
116328

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:116328

UCSC genome browser

More...
UCSCi
uc003xyb.4 human [Q49A92-6]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB056652 mRNA Translation: BAB64433.1
AK094191 mRNA Translation: BAC04304.1
AK094650 mRNA Translation: BAC04395.1
AK291436 mRNA Translation: BAF84125.1
AL834454 mRNA Translation: CAD39114.2
AC011884 Genomic DNA No translation available.
AC067871 Genomic DNA No translation available.
AC083967 Genomic DNA No translation available.
AC090096 Genomic DNA No translation available.
KF458778 Genomic DNA No translation available.
KF458774 Genomic DNA No translation available.
CH471068 Genomic DNA Translation: EAW86947.1
CH471068 Genomic DNA Translation: EAW86949.1
BC041961 mRNA Translation: AAH41961.1 Sequence problems.
CCDSiCCDS6203.2 [Q49A92-6]
RefSeqiNP_443190.2, NM_052958.2 [Q49A92-6]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi125497, 6 interactors
IntActiQ49A92, 2 interactors
STRINGi9606.ENSP00000427820

PTM databases

iPTMnetiQ49A92
PhosphoSitePlusiQ49A92

Polymorphism and mutation databases

BioMutaiC8orf34
DMDMi187470865

Proteomic databases

MassIVEiQ49A92
PaxDbiQ49A92
PeptideAtlasiQ49A92
PRIDEiQ49A92
ProteomicsDBi33789
62033 [Q49A92-2]
62034 [Q49A92-3]
62035 [Q49A92-4]

Genome annotation databases

EnsembliENST00000325233; ENSP00000319532; ENSG00000165084 [Q49A92-4]
ENST00000337103; ENSP00000337174; ENSG00000165084 [Q49A92-2]
ENST00000348340; ENSP00000345255; ENSG00000165084 [Q49A92-3]
ENST00000518698; ENSP00000427820; ENSG00000165084 [Q49A92-6]
GeneIDi116328
KEGGihsa:116328
UCSCiuc003xyb.4 human [Q49A92-6]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
116328
DisGeNETi116328
EuPathDBiHostDB:ENSG00000165084.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C8orf34
HGNCiHGNC:30905 C8orf34
HPAiHPA044420
HPA053065
neXtProtiNX_Q49A92
OpenTargetsiENSG00000165084
PharmGKBiPA142672353

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IFD0 Eukaryota
ENOG4111YR7 LUCA
GeneTreeiENSGT00390000005870
HOGENOMiHOG000060121
InParanoidiQ49A92
OMAiNQGRATY
OrthoDBi667565at2759
PhylomeDBiQ49A92
TreeFamiTF332826

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
C8orf34 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
116328
PharosiQ49A92 Tdark

Protein Ontology

More...
PROi
PR:Q49A92
RNActiQ49A92 protein

Gene expression databases

BgeeiENSG00000165084 Expressed in 117 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiQ49A92 baseline and differential
GenevisibleiQ49A92 HS

Family and domain databases

InterProiView protein in InterPro
IPR040687 DUF5586
PANTHERiPTHR32000 PTHR32000, 2 hits
PfamiView protein in Pfam
PF17824 DUF5586, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCH034_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q49A92
Secondary accession number(s): A0A0C4DFS7
, A8K5X1, G3XAM6, Q8N1X0, Q8N9M7, Q8ND19, Q96Q28
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: March 28, 2018
Last modified: December 11, 2019
This is version 111 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again