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Protein
Submitted name:

NRXN1 protein

Gene

NRXN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NRXN1 proteinImported
Gene namesi
Name:NRXN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31786

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500423496826 – 278Sequence analysisAdd BLAST253

Proteomic databases

PeptideAtlasiQ49A31

Expressioni

Gene expression databases

GenevisibleiQ49A31 HS

Structurei

3D structure databases

ProteinModelPortaliQ49A31
SMRiQ49A31
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 217LAM_G_DOMAINInterPro annotationAdd BLAST188
Domaini219 – 256EGF-likeInterPro annotationAdd BLAST38

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000170077
HOVERGENiHBG085181

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR001791 Laminin_G
PfamiView protein in Pfam
PF02210 Laminin_G_2, 1 hit
SMARTiView protein in SMART
SM00282 LamG, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit
PS50025 LAM_G_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q49A31-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGTALLQRGG CFLLCLSLLL LGCWAELGSG LEFPGAEGQW TRFPKWNACC
60 70 80 90 100
ESEMSFQLKT RSARGLVLYF DDEGFCDFLE LILTRGGRLQ LSFSVFCAEP
110 120 130 140 150
ATLLADTPVN DGAWHSVRIR RQFRNTTLFI DQVEAKWVEV KSKRRDMTVF
160 170 180 190 200
SGLFVGGLPP ELRAAALKLT LASVREREPF KGWIRDVGVN SSQVLPVDSG
210 220 230 240 250
EVKLDDEPPN SGGGSPCEAG EEGEGGVCLN GGVCSVVDDQ AVCDCSRTGF
260 270
RGKDCSQEDN NVEGLAHLMM GDQGKSKD
Length:278
Mass (Da):30,257
Last modified:September 13, 2005 - v1
Checksum:i99A2F81B87FA5CA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046631 mRNA Translation: AAH46631.1
UniGeneiHs.637685

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046631 mRNA Translation: AAH46631.1
UniGeneiHs.637685

3D structure databases

ProteinModelPortaliQ49A31
SMRiQ49A31
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ49A31

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

PharmGKBiPA31786

Phylogenomic databases

HOGENOMiHOG000170077
HOVERGENiHBG085181

Miscellaneous databases

ChiTaRSiNRXN1 human
GenomeRNAii9378

Gene expression databases

GenevisibleiQ49A31 HS

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR001791 Laminin_G
PfamiView protein in Pfam
PF02210 Laminin_G_2, 1 hit
SMARTiView protein in SMART
SM00282 LamG, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit
PS50025 LAM_G_DOMAIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ49A31_HUMAN
AccessioniPrimary (citable) accession number: Q49A31
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 7, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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