UniProtKB - Q499Y8 (Q499Y8_HUMAN)
Protein
Submitted name:
MAPK10 protein
Gene
MAPK10
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- MAP kinase activity Source: InterPro
GO - Biological processi
- rhythmic process Source: UniProtKB-KW
Keywordsi
Biological process | Biological rhythmsARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: MAPK10 proteinImported |
Gene namesi | Name:MAPK10Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000109339.18 |
PTM / Processingi
Proteomic databases
MaxQBi | Q499Y8 |
PeptideAtlasi | Q499Y8 |
PRIDEi | Q499Y8 |
ProteomicsDBi | 62006 |
Expressioni
Gene expression databases
Bgeei | ENSG00000109339, Expressed in frontal cortex and 198 other tissues |
ExpressionAtlasi | Q499Y8, baseline and differential |
Interactioni
Binary interactionsi
Q499Y8
With | #Exp. | IntAct |
---|---|---|
LDHA - isoform 3 [P00338-3] | 3 | EBI-10241715,EBI-10195200 |
Protein-protein interaction databases
IntActi | Q499Y8, 1 interactor |
Family & Domainsi
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR008351, MAPK_JNK IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
PRINTSi | PR01772, JNKMAPKINASE |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
Q499Y8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MELMDANLCQ VIQMELDHER MSYLLYQMLC GIKHLHSAGI IHRDLKPSNI
60 70 80 90 100
VVKSDCTLKI LDFGLARTAG TSFMMTPYVV TRYYRAPEVI LGMGYKENVD
110 120 130 140 150
MWSVGCIMGE MIKGAVLFPG TDHIDQWNKV IEQLGTPCPE FMKKLQPTVR
160 170 180 190 200
NYVENRPKYA GLTFPKLFPD SLFPADSEHN KLKASQARDL LSKMLVIDPA
210 220 230 240 250
KRISVDDALQ HPYINVWYDP AEVEAPPPQI YDKQLDEREH TIEEWKELIY
260 270 280 290 300
KEVMNSEEKT KNGVVKGQPS PSGAAVNSSE SLPPSSSVND ISSMSTDQTL
310
ASDTDSSLEA SAGPLGCCR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC051731 mRNA Translation: AAH51731.1 |
RefSeqi | NP_001304997.1, NM_001318068.1 XP_016863938.1, XM_017008449.1 XP_016863939.1, XM_017008450.1 |
Genome annotation databases
GeneIDi | 5602 |
UCSCi | uc062xyf.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC051731 mRNA Translation: AAH51731.1 |
RefSeqi | NP_001304997.1, NM_001318068.1 XP_016863938.1, XM_017008449.1 XP_016863939.1, XM_017008450.1 |
3D structure databases
SMRi | Q499Y8 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q499Y8, 1 interactor |
Proteomic databases
MaxQBi | Q499Y8 |
PeptideAtlasi | Q499Y8 |
PRIDEi | Q499Y8 |
ProteomicsDBi | 62006 |
Genome annotation databases
GeneIDi | 5602 |
UCSCi | uc062xyf.1, human |
Organism-specific databases
CTDi | 5602 |
EuPathDBi | HostDB:ENSG00000109339.18 |
Miscellaneous databases
BioGRID-ORCSi | 5602, 5 hits in 876 CRISPR screens |
ChiTaRSi | MAPK10, human |
GenomeRNAii | 5602 |
Gene expression databases
Bgeei | ENSG00000109339, Expressed in frontal cortex and 198 other tissues |
ExpressionAtlasi | Q499Y8, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR008351, MAPK_JNK IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
PRINTSi | PR01772, JNKMAPKINASE |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q499Y8_HUMAN | |
Accessioni | Q499Y8Primary (citable) accession number: Q499Y8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 13, 2005 |
Last sequence update: | September 13, 2005 | |
Last modified: | December 2, 2020 | |
This is version 133 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |