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Protein

Ankyrin repeat and death domain-containing protein 1A

Gene

ANKDD1A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ankyrin repeat and death domain-containing protein 1A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANKDD1A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000166839.16

Human Gene Nomenclature Database

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HGNCi
HGNC:28002 ANKDD1A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q495B1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000166839

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485299

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ANKDD1A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
288558803

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002878821 – 522Ankyrin repeat and death domain-containing protein 1AAdd BLAST522

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q495B1

PeptideAtlas

More...
PeptideAtlasi
Q495B1

PRoteomics IDEntifications database

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PRIDEi
Q495B1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
61950
61951 [Q495B1-1]
61952 [Q495B1-2]
61953 [Q495B1-6]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q495B1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q495B1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000166839 Expressed in 179 organ(s), highest expression level in tendon

CleanEx database of gene expression profiles

More...
CleanExi
HS_ANKDD1A

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q495B1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q495B1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040757

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
131506, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q495B1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000369579

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q495B1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q495B1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati14 – 43ANK 1Add BLAST30
Repeati47 – 76ANK 2Add BLAST30
Repeati90 – 119ANK 3Add BLAST30
Repeati123 – 152ANK 4Add BLAST30
Repeati158 – 187ANK 5Add BLAST30
Repeati191 – 220ANK 6Add BLAST30
Repeati224 – 253ANK 7Add BLAST30
Repeati257 – 286ANK 8Add BLAST30
Repeati290 – 319ANK 9Add BLAST30
Repeati323 – 352ANK 10Add BLAST30
Repeati356 – 385ANK 11Add BLAST30
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini413 – 501DeathPROSITE-ProRule annotationAdd BLAST89

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4177 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154170

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000273862

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG100885

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q495B1

Identification of Orthologs from Complete Genome Data

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OMAi
HAIEQQW

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0IU8

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q495B1

TreeFam database of animal gene trees

More...
TreeFami
TF333615

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 4 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039194 AKD1A/AKD1B
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain

The PANTHER Classification System

More...
PANTHERi
PTHR24125 PTHR24125, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 8 hits
PS50017 DEATH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 5 (identifier: Q495B1-5) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQEELAWETD GLLPLERQLH EAARQNNVGR MQELIGRRVN TRARNHVGRV
60 70 80 90 100
ALHWAAGAGH EQAVRLLLEH EAAVDEEDAV GALTEARLCF GMNALLLSAW
110 120 130 140 150
FGHLRILQIL VNSGAKIHCE SKDGLTLLHC AAQKGHVPVL AFIMEDLEDV
160 170 180 190 200
ALDHVDKLGR TAFHRAAEHG QLDALDFLVG SGCDHNVKDK EGNTALHLAA
210 220 230 240 250
GRGHMAVLQR LVDIGLDLEE QNAEGLTALH SAAGGSHPDC VQLLLRAGST
260 270 280 290 300
VNALTQKNLS CLHYAALSGS EDVSRVLIHA GGCANVVDHQ GASPLHLAVR
310 320 330 340 350
HNFPALVRLL INSDSDVNAV DNRQQTPLHL AAEHAWQDIA DMLLIAGVDL
360 370 380 390 400
NLRDKQGKTA LAVAVRSNHV SLVDMIIKAD RFYRWEKDHP SDPSGKSLSF
410 420 430 440 450
KQDHRQETQQ LRSVLWRLAS RYLQPREWKK LAYSWEFTEA HVDAIEQQWT
460 470 480 490 500
GTRSYQEHGH RMLLIWLHGV ATAGENPSKA LFEGLVAIGR RDLAGWSTMA
510 520
RSQLTATSAS RVQMILVPQP PE
Length:522
Mass (Da):57,550
Last modified:February 9, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB0A26B4EE684A8B5
GO
Isoform 2 (identifier: Q495B1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     355-386: Missing.

Show »
Length:490
Mass (Da):53,865
Checksum:iE2D045FB6FEDC233
GO
Isoform 3 (identifier: Q495B1-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     13-41: LPLERQLHEAARQNNVGRMQELIGRRVNT → WDECASPVCLVRPLTNPLDLDKLRGQDPL
     42-522: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Show »
Length:41
Mass (Da):4,668
Checksum:i0BB1F50CE27655CF
GO
Isoform 1 (identifier: Q495B1-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     495-522: GWSTMARSQLTATSASRVQMILVPQPPE → ENIRKKANAAPSAPRRCTAM

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Show »
Length:514
Mass (Da):56,692
Checksum:i8ABB76F55F8C6A6F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DFZ5A0A0C4DFZ5_HUMAN
Ankyrin repeat and death domain-con...
ANKDD1A
399Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DGZ7A0A0C4DGZ7_HUMAN
Ankyrin repeat and death domain-con...
ANKDD1A
423Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DGA8A0A0C4DGA8_HUMAN
Ankyrin repeat and death domain con...
ANKDD1A hCG_2004016
181Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8TAJ8Q8TAJ8_HUMAN
ANKDD1A protein
ANKDD1A
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RD28D6RD28_HUMAN
Ankyrin repeat and death domain-con...
ANKDD1A
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC05399 differs from that shown. Probable cloning artifact.Curated
The sequence BAC11532 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032358355K → E1 PublicationCorresponds to variant dbSNP:rs34988193Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03867613 – 41LPLER…RRVNT → WDECASPVCLVRPLTNPLDL DKLRGQDPL in isoform 3. 1 PublicationAdd BLAST29
Alternative sequenceiVSP_03867742 – 522Missing in isoform 3. 1 PublicationAdd BLAST481
Alternative sequenceiVSP_038678355 – 386Missing in isoform 2. 1 PublicationAdd BLAST32
Alternative sequenceiVSP_038675495 – 522GWSTM…PQPPE → ENIRKKANAAPSAPRRCTAM in isoform 1. 1 PublicationAdd BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK075298 mRNA Translation: BAC11532.1 Sequence problems.
AK098736 mRNA Translation: BAC05399.1 Sequence problems.
AC069368 Genomic DNA No translation available.
BC101273 mRNA Translation: AAI01274.1
BC101274 mRNA Translation: AAI01275.1
BC101275 mRNA Translation: AAI01276.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10197.2 [Q495B1-5]

NCBI Reference Sequences

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RefSeqi
NP_874362.3, NM_182703.5 [Q495B1-5]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.207157

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000319580; ENSP00000325895; ENSG00000166839 [Q495B1-5]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
348094

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:348094

UCSC genome browser

More...
UCSCi
uc002anz.4 human [Q495B1-5]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075298 mRNA Translation: BAC11532.1 Sequence problems.
AK098736 mRNA Translation: BAC05399.1 Sequence problems.
AC069368 Genomic DNA No translation available.
BC101273 mRNA Translation: AAI01274.1
BC101274 mRNA Translation: AAI01275.1
BC101275 mRNA Translation: AAI01276.1
CCDSiCCDS10197.2 [Q495B1-5]
RefSeqiNP_874362.3, NM_182703.5 [Q495B1-5]
UniGeneiHs.207157

3D structure databases

ProteinModelPortaliQ495B1
SMRiQ495B1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131506, 2 interactors
IntActiQ495B1, 1 interactor
STRINGi9606.ENSP00000369579

PTM databases

iPTMnetiQ495B1
PhosphoSitePlusiQ495B1

Polymorphism and mutation databases

BioMutaiANKDD1A
DMDMi288558803

Proteomic databases

PaxDbiQ495B1
PeptideAtlasiQ495B1
PRIDEiQ495B1
ProteomicsDBi61950
61951 [Q495B1-1]
61952 [Q495B1-2]
61953 [Q495B1-6]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000319580; ENSP00000325895; ENSG00000166839 [Q495B1-5]
GeneIDi348094
KEGGihsa:348094
UCSCiuc002anz.4 human [Q495B1-5]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
348094
EuPathDBiHostDB:ENSG00000166839.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ANKDD1A
HGNCiHGNC:28002 ANKDD1A
HPAiHPA040757
neXtProtiNX_Q495B1
OpenTargetsiENSG00000166839
PharmGKBiPA143485299

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000154170
HOGENOMiHOG000273862
HOVERGENiHBG100885
InParanoidiQ495B1
OMAiHAIEQQW
OrthoDBiEOG091G0IU8
PhylomeDBiQ495B1
TreeFamiTF333615

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ANKDD1A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
348094

Protein Ontology

More...
PROi
PR:Q495B1

Gene expression databases

BgeeiENSG00000166839 Expressed in 179 organ(s), highest expression level in tendon
CleanExiHS_ANKDD1A
ExpressionAtlasiQ495B1 baseline and differential
GenevisibleiQ495B1 HS

Family and domain databases

CDDicd00204 ANK, 4 hits
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR039194 AKD1A/AKD1B
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
PANTHERiPTHR24125 PTHR24125, 1 hit
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 10 hits
SUPFAMiSSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 8 hits
PS50017 DEATH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAKD1A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q495B1
Secondary accession number(s): Q495B2
, Q495B3, Q8N7A0, Q8NBS5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: February 9, 2010
Last modified: December 5, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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