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Entry version 107 (17 Jun 2020)
Sequence version 1 (13 Sep 2005)
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Protein

Cilia- and flagella-associated protein 100

Gene

CFAP100

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cilia- and flagella-associated protein 100Curated
Alternative name(s):
Coiled-coil domain-containing protein 37Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CFAP100Imported
Synonyms:CCDC37Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000163885.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26842 CFAP100

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q494V2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
348807

Open Targets

More...
OpenTargetsi
ENSG00000163885

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672192

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q494V2 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CFAP100

Domain mapping of disease mutations (DMDM)

More...
DMDMi
97045019

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002344871 – 611Cilia- and flagella-associated protein 100Add BLAST611

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q494V2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q494V2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q494V2

PeptideAtlas

More...
PeptideAtlasi
Q494V2

PRoteomics IDEntifications database

More...
PRIDEi
Q494V2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
61941 [Q494V2-1]
61942 [Q494V2-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q494V2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q494V2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000163885 Expressed in right uterine tube and 114 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q494V2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q494V2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000163885 Tissue enhanced (brain, fallopian tube, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
131533, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q494V2, 6 interactors

Molecular INTeraction database

More...
MINTi
Q494V2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000344749

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q494V2 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q494V2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili101 – 128Sequence analysisAdd BLAST28
Coiled coili164 – 203Sequence analysisAdd BLAST40
Coiled coili230 – 257Sequence analysisAdd BLAST28
Coiled coili393 – 432Sequence analysisAdd BLAST40
Coiled coili526 – 578Sequence analysisAdd BLAST53

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CFAP100 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFH9 Eukaryota
ENOG410YEAI LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153110

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_026271_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q494V2

Identification of Orthologs from Complete Genome Data

More...
OMAi
HQKMTYS

Database of Orthologous Groups

More...
OrthoDBi
1092113at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q494V2

TreeFam database of animal gene trees

More...
TreeFami
TF328835

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025252 DUF4200

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13863 DUF4200, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q494V2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSEIPSTIVS KNMTNDKNSL ESMNISSSSS TEENPKKQAR KNEEHGPDPS
60 70 80 90 100
ANPFHLSGDV DFFLLRDQER NKALSERQQQ KTMRVHQKMT YSSKVSAKHT
110 120 130 140 150
SLRRQLQLED KQEDLEARAE AEHQRAFRDY TTWKLTLTKE KNVEPENMSG
160 170 180 190 200
YIKQKRQMFL LQYALDVKRR EIQRLETLAT KEEARLERAE KSLEKDAALF
210 220 230 240 250
DEFVRENDCS SVQAMRAAEK ETKAKIEKIL EIRDLTTQIV NIKSEISRFE
260 270 280 290 300
DTLKHYKVYK DFLYKLSPKE WLEEQEKKHS FLKKAKEVSE ASKESSVNST
310 320 330 340 350
PGDKGPGIKG KASSMWAKEG QGTKKPWRFL QTMRLGRSPS YLSSPQQGSQ
360 370 380 390 400
PSESSGGDSR GSNSPIPPTQ EDTDSDGEEP QLYFTEPQQL LDVFRELEEQ
410 420 430 440 450
NLSLIQNSQE TEKTLEELSH TLKHTQIRMD REVNQLKQWV TTMMMSITKE
460 470 480 490 500
EDTAAELELK ARVFHFGEYK GDQQDKLLES LNCKVLDVYR HCTGTQQEAN
510 520 530 540 550
LGTVQMLTII EHQLDELLEN LEHVPQVKIE QAERAKEKER RIRLREEKLQ
560 570 580 590 600
MQKILQEEHL QRARARAQAE IKKKRGRTLV CRSRPPAHRI KQQSEHTLMD
610
KEEEELLFFF T
Length:611
Mass (Da):71,117
Last modified:September 13, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i34949CC07299588A
GO
Isoform 2 (identifier: Q494V2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     139-139: K → KA

Show »
Length:612
Mass (Da):71,188
Checksum:i6CAD9DFE50B83970
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PQV5E9PQV5_HUMAN
Cilia- and flagella-associated prot...
CFAP100
117Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti36K → E in BAC05035 (PubMed:14702039).Curated1
Sequence conflicti244S → G in BAC05035 (PubMed:14702039).Curated1
Sequence conflicti412Missing in AAI01370 (PubMed:15489334).Curated1
Sequence conflicti412Missing in AAI01368 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_018328139K → KA in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK097402 mRNA Translation: BAC05035.1
CH471052 Genomic DNA Translation: EAW79363.1
CH471052 Genomic DNA Translation: EAW79364.1
BC101366 mRNA Translation: AAI01367.1
BC101367 mRNA Translation: AAI01368.2
BC101368 mRNA Translation: AAI01369.1
BC101369 mRNA Translation: AAI01370.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3037.1 [Q494V2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_872434.2, NM_182628.2 [Q494V2-1]
XP_006713686.1, XM_006713623.2 [Q494V2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000352312; ENSP00000344749; ENSG00000163885 [Q494V2-1]
ENST00000505024; ENSP00000423046; ENSG00000163885 [Q494V2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
348807

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:348807

UCSC genome browser

More...
UCSCi
uc003eiu.1 human [Q494V2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK097402 mRNA Translation: BAC05035.1
CH471052 Genomic DNA Translation: EAW79363.1
CH471052 Genomic DNA Translation: EAW79364.1
BC101366 mRNA Translation: AAI01367.1
BC101367 mRNA Translation: AAI01368.2
BC101368 mRNA Translation: AAI01369.1
BC101369 mRNA Translation: AAI01370.1
CCDSiCCDS3037.1 [Q494V2-1]
RefSeqiNP_872434.2, NM_182628.2 [Q494V2-1]
XP_006713686.1, XM_006713623.2 [Q494V2-1]

3D structure databases

SMRiQ494V2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi131533, 4 interactors
IntActiQ494V2, 6 interactors
MINTiQ494V2
STRINGi9606.ENSP00000344749

PTM databases

iPTMnetiQ494V2
PhosphoSitePlusiQ494V2

Polymorphism and mutation databases

BioMutaiCFAP100
DMDMi97045019

Proteomic databases

jPOSTiQ494V2
MassIVEiQ494V2
PaxDbiQ494V2
PeptideAtlasiQ494V2
PRIDEiQ494V2
ProteomicsDBi61941 [Q494V2-1]
61942 [Q494V2-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
46637 139 antibodies

Genome annotation databases

EnsembliENST00000352312; ENSP00000344749; ENSG00000163885 [Q494V2-1]
ENST00000505024; ENSP00000423046; ENSG00000163885 [Q494V2-2]
GeneIDi348807
KEGGihsa:348807
UCSCiuc003eiu.1 human [Q494V2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
348807
DisGeNETi348807
EuPathDBiHostDB:ENSG00000163885.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CFAP100
HGNCiHGNC:26842 CFAP100
HPAiENSG00000163885 Tissue enhanced (brain, fallopian tube, testis)
neXtProtiNX_Q494V2
OpenTargetsiENSG00000163885
PharmGKBiPA142672192

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IFH9 Eukaryota
ENOG410YEAI LUCA
GeneTreeiENSGT00940000153110
HOGENOMiCLU_026271_0_1_1
InParanoidiQ494V2
OMAiHQKMTYS
OrthoDBi1092113at2759
PhylomeDBiQ494V2
TreeFamiTF328835

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
348807 1 hit in 784 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CFAP100 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
348807
PharosiQ494V2 Tdark

Protein Ontology

More...
PROi
PR:Q494V2
RNActiQ494V2 protein

Gene expression databases

BgeeiENSG00000163885 Expressed in right uterine tube and 114 other tissues
ExpressionAtlasiQ494V2 baseline and differential
GenevisibleiQ494V2 HS

Family and domain databases

InterProiView protein in InterPro
IPR025252 DUF4200
PfamiView protein in Pfam
PF13863 DUF4200, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCP100_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q494V2
Secondary accession number(s): D3DNA8
, Q494V1, Q494V4, Q8N838
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: September 13, 2005
Last modified: June 17, 2020
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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