UniProtKB - Q49430 (Y390_MYCGE)
Protein
Putative ABC transporter ATP-binding MG390
Gene
MG390
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 12 | PROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 494 – 501 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ATPase-coupled transmembrane transporter activity Source: GO_Central
- ATP binding Source: UniProtKB-KW
- cysteine-type peptidase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase, Protease, Thiol protease |
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | MGEN243273:G1GJ2-486-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative ABC transporter ATP-binding MG390 |
Gene namesi | Ordered Locus Names:MG390 |
Organismi | Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) |
Taxonomic identifieri | 243273 [NCBI] |
Taxonomic lineagei | Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 150 – 170 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 188 – 208 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 265 – 285 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 290 – 310 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 379 – 399 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 402 – 422 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093247 | 1 – 660 | Putative ABC transporter ATP-binding MG390Add BLAST | 660 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 126 | Peptidase C39PROSITE-ProRule annotationAdd BLAST | 121 | |
Domaini | 464 – 657 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 194 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2274, Bacteria |
HOGENOMi | CLU_488191_0_0_14 |
OMAi | IVGFIRH |
OrthoDBi | 643917at2 |
Family and domain databases
InterProi | View protein in InterPro IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like IPR027417, P-loop_NTPase IPR005074, Peptidase_C39 |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF03412, Peptidase_C39, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF90123, SSF90123, 1 hit |
PROSITEi | View protein in PROSITE PS50990, PEPTIDASE_C39, 1 hit |
i Sequence
Sequence statusi: Complete.
Q49430-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKIIYQEQQN ECGICVIGML ANAIHDEKYV HDELLEQINL PPNGLSLFEM
60 70 80 90 100
ESYGKKFGLE INSYQLTFQE LKELDSKFII VHFKDHFVIV KNKHENSWEV
110 120 130 140 150
YDPAKGKYLL TDEKLEKLWT GYAATVAKAF KEIPPVNKSN FFSNFFDFNL
160 170 180 190 200
VTFYVFIELI IIGISTLLAT ASRTIITNTV DFGTAVNLVV LVVYFSCLKG
210 220 230 240 250
LNLLLQVILQ LIRNFLFWKQ YRGYLGWIIQ SLQQKSFVYF SNKSPNQLIE
260 270 280 290 300
RQFYLKEVLS FFNFYIPNLI ISCVVALIIG VLIGINQLEF LLIAIAQIVV
310 320 330 340 350
NAGLFCYDFF FTKKITKKEI PYVELQNKIS LQLDENLREE QNKKRFNFLM
360 370 380 390 400
LNFRKALLQN QNINNQKEIN RLTIENIKSF FQQGFDFAIL GLGVIGIIEQ
410 420 430 440 450
RYQLSFLFYV FGIQSLFSTY ATRIVQFGAA INIYHYCREK LVNLFIETKK
460 470 480 490 500
DEGIKVNWQC PDEISLENLS VTLNQHVDLA NLSLKIKNET VIFGQNGSGK
510 520 530 540 550
STFLKILTGR GFEYTGNIKF NNVDLKRCSK EQLFENVYYL KGQNLMQTEA
560 570 580 590 600
NDFGFSEALF NNQNPHIYQL LFDAGVQNQT KLSSGQKQIL QLFLLSNIKN
610 620 630 640 650
KVILLDECMN AIAPEIKNRV YQLLVKPLTL NNFVVLVEHD LSFASEAQNK
660
INLTNYLRNS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 392 | L → F in AAA03404 (PubMed:8253680).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L43967 Genomic DNA Translation: AAC71618.1 U02248 Genomic DNA Translation: AAA03404.1 U02218 Genomic DNA Translation: AAA03372.1 |
PIRi | B64243 |
RefSeqi | WP_010869463.1, NC_000908.2 |
Genome annotation databases
EnsemblBacteriai | AAC71618; AAC71618; MG_390 |
KEGGi | mge:MG_390 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L43967 Genomic DNA Translation: AAC71618.1 U02248 Genomic DNA Translation: AAA03404.1 U02218 Genomic DNA Translation: AAA03372.1 |
PIRi | B64243 |
RefSeqi | WP_010869463.1, NC_000908.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 243273.MG_390 |
Genome annotation databases
EnsemblBacteriai | AAC71618; AAC71618; MG_390 |
KEGGi | mge:MG_390 |
Phylogenomic databases
eggNOGi | COG2274, Bacteria |
HOGENOMi | CLU_488191_0_0_14 |
OMAi | IVGFIRH |
OrthoDBi | 643917at2 |
Enzyme and pathway databases
BioCyci | MGEN243273:G1GJ2-486-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like IPR027417, P-loop_NTPase IPR005074, Peptidase_C39 |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF03412, Peptidase_C39, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF90123, SSF90123, 1 hit |
PROSITEi | View protein in PROSITE PS50990, PEPTIDASE_C39, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y390_MYCGE | |
Accessioni | Q49430Primary (citable) accession number: Q49430 Secondary accession number(s): Q49332, Q49356 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | February 10, 2021 | |
This is version 126 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families