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Entry version 89 (11 Dec 2019)
Sequence version 1 (01 Nov 1996)
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Protein

Protein P200

Gene

MG386

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Could be an accessory structural component in cytadherence.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCytadherence

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MGEN243273:G1GJ2-482-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein P200
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:MG386
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri243273 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000807 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000581271 – 1616Protein P200Add BLAST1616

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
243273.MG_386

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q49429

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1161 – 11862-1Add BLAST26
Repeati1205 – 12361-1Add BLAST32
Repeati1310 – 13392-2Add BLAST30
Repeati1358 – 13891-2Add BLAST32

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni891 – 13892 X 26 AA repeatsAdd BLAST499
Regioni1205 – 13892 X 32 AA repeatsAdd BLAST185

Keywords - Domaini

Repeat

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
NYDFDEP

Database of Orthologous Groups

More...
OrthoDBi
2028499at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1660.50, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022466 AGR_box
IPR038145 EAGR_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16713 EAGR_box, 5 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03834 EAGR_box, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q49429-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKTTKNKNK NTTPKSKTKK YLESANKKSV TKPKKEQDKV ENLFDQPFLG
60 70 80 90 100
EIKKNILKKT KSFNSKKKET VKSKSKSPID FFDETKRGVF IVPPETDILS
110 120 130 140 150
RRELNQKTVV NTVPNQTSSY PTINENKLVE LNNQPETKVL ETKKDSFTTT
160 170 180 190 200
IREKKLNPED SQAFWYIFVG DRKYGFWKNH TWVWLGYFDQ LQRWNYFKVI
210 220 230 240 250
ETVEVPQEHA AFIKQRPADI DFWRPLVGNP NYGFVQNNTW IWKGFFDKKL
260 270 280 290 300
NWIPDPVRFT EEALGHTDSL VDEIEKKTIS EQPYWEQEND IVVTVFNTKS
310 320 330 340 350
LASSLENELL LENSSEEQPV IEEVKPRRNE VIFRNPVTKL HFEKEKFEFL
360 370 380 390 400
NPVKETNETI PLIEIVKEEV KVESEVEAPV EIEPEAACEP ETTIPEVETV
410 420 430 440 450
FVYEDDLKGL DSNQTQAGNV PEVETVFVYE DDLKGLDSII KDDQQHDEIA
460 470 480 490 500
KHVEHLSQDY SKEIKDSAKA DLSNISDDID SVWKEFGSFT DETQKSVEEK
510 520 530 540 550
SQVDEIILDA NNDFINESLF RDEVVNNIDS QINETVSEQQ FEPTYSVNEF
560 570 580 590 600
QQEFSEPVVS DEKIKETNSD ESVNTDLTAL FSEKLVNEVL LTNEYVDVNA
610 620 630 640 650
PFSTETEVKV SSELPKSELV DEITFINNDP KPQEGLEYKV DFLETEPKSL
660 670 680 690 700
FDEKTTIVVE SEPPFIQPDL SLELDSVNDV DKSLETKTTS VELNHEEIGN
710 720 730 740 750
EFINLDVSEK EVQEQPTTQL ETDSEFVLPT YQIVEDSFTE SAETPNEFSS
760 770 780 790 800
EQKDTLEFIS QTQEVETSES NVPTVEQETK LFEHQDENNL FTPLPLDLTE
810 820 830 840 850
IIESNALFDS KPDEKESSDS ELQPTFKEIK LDSTVEVPQE SSQVEATFDT
860 870 880 890 900
VQPEAVFDEI KTQELQPEAT TEVVFDDHFQ PDVQPEQTPQ EAKFDSPVEI
910 920 930 940 950
PQESSQAEFH AEQISDEIKL EEKTEAVFDH QQLENQSEET VVTPTEVTAF
960 970 980 990 1000
EPETIETQLE PSSEDQPSEP ALDQNHPEIV TAEVEQIFDG TKLEDLKLEE
1010 1020 1030 1040 1050
ANFDNVENNE VQPKETEAEI TFDETKELQQ ETSSEPLSTE ELKSEATFDN
1060 1070 1080 1090 1100
VSEAESEAVF EKPQLETQTE KILEEEPKSE PVDQLITEAS FDTVKHEAVF
1110 1120 1130 1140 1150
DKNQTQTEGL EEPQVSSEAE VVDQTTTDTV GEPEAVFDVQ PEKTTEVKFD
1160 1170 1180 1190 1200
DVENQQKVIS EPQVEQQPGE AVFEPSAEAK FDSPVESVQD SQPEPVLEEV
1210 1220 1230 1240 1250
QTQPEIQPVE SQPEATFDTV QPEQTPQEAK FDSPVETVEQ PEFSSEPTQQ
1260 1270 1280 1290 1300
HVESEASFDE PNYDFDEPNY DFDQPSYDSD LQPSEPQYDV DEPNYDFDEP
1310 1320 1330 1340 1350
NYEIESKPSE PQFEPQVEQQ PGEAVFEPSA EAKFDSPVES VQDSQPEPLL
1360 1370 1380 1390 1400
EEVQTQPEIQ PVESQPEATF DTVQPEQTPQ EAKFDSPVET IQEPQVSSEP
1410 1420 1430 1440 1450
EVVVQPNFEE RKPETVLEEP QADEIQPEAS EEESLDWELL VGNNSYGHYE
1460 1470 1480 1490 1500
PDGEWVWAGF FGDDQKWNKD ATVKWARERD YLPLIGDEVY GRYNNKGEWI
1510 1520 1530 1540 1550
WYGFYDESGD WVLVDEQWKN RQPRINEAPK FWEKLIGNEE YGYYEDNEWN
1560 1570 1580 1590 1600
WYDGEFDSEG NWLVFQSEET ENLNEDITKD IPALEGYDID SIDADEWLSQ
1610
FSADDAKDVF GSNDKK
Length:1,616
Mass (Da):185,679
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6AF76A13AC49E4FF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti256P → S in AAA03400 (PubMed:8253680).Curated1
Sequence conflicti304S → F in AAA03400 (PubMed:8253680).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L43967 Genomic DNA Translation: AAC71613.1
U02245 Genomic DNA Translation: AAA03400.1
U02175 Genomic DNA Translation: AAD12458.1
U02126 Genomic DNA Translation: AAD12402.1

Protein sequence database of the Protein Information Resource

More...
PIRi
G64242

NCBI Reference Sequences

More...
RefSeqi
WP_010869461.1, NC_000908.2

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC71613; AAC71613; MG_386

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mge:MG_386

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA Translation: AAC71613.1
U02245 Genomic DNA Translation: AAA03400.1
U02175 Genomic DNA Translation: AAD12458.1
U02126 Genomic DNA Translation: AAD12402.1
PIRiG64242
RefSeqiWP_010869461.1, NC_000908.2

3D structure databases

SMRiQ49429
ModBaseiSearch...

Protein-protein interaction databases

STRINGi243273.MG_386

Genome annotation databases

EnsemblBacteriaiAAC71613; AAC71613; MG_386
KEGGimge:MG_386

Phylogenomic databases

OMAiNYDFDEP
OrthoDBi2028499at2

Enzyme and pathway databases

BioCyciMGEN243273:G1GJ2-482-MONOMER

Family and domain databases

Gene3Di1.10.1660.50, 5 hits
InterProiView protein in InterPro
IPR022466 AGR_box
IPR038145 EAGR_sf
PfamiView protein in Pfam
PF16713 EAGR_box, 5 hits
TIGRFAMsiTIGR03834 EAGR_box, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP200_MYCGE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q49429
Secondary accession number(s): Q49259
, Q49298, Q49352, Q49353
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: December 11, 2019
This is version 89 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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