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Entry version 97 (02 Jun 2021)
Sequence version 1 (01 Nov 1997)
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Protein

Uncharacterized protein MG277

Gene

MG277

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MGEN243273:G1GJ2-335-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein MG277
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:MG277
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri243273 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000807 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Transmembranei515 – 535HelicalSequence analysisAdd BLAST21
Transmembranei537 – 557HelicalSequence analysisAdd BLAST21
Transmembranei558 – 578HelicalSequence analysisAdd BLAST21
Transmembranei614 – 634HelicalSequence analysisAdd BLAST21
Transmembranei645 – 665HelicalSequence analysisAdd BLAST21
Transmembranei726 – 746HelicalSequence analysisAdd BLAST21
Transmembranei762 – 782HelicalSequence analysisAdd BLAST21
Transmembranei789 – 809HelicalSequence analysisAdd BLAST21
Transmembranei816 – 836HelicalSequence analysisAdd BLAST21
Transmembranei877 – 897HelicalSequence analysisAdd BLAST21
Transmembranei903 – 923HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002105021 – 970Uncharacterized protein MG277Add BLAST970

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
243273.MG_277

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni366 – 387DisorderedSequence analysisAdd BLAST22

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0841, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_304380_0_0_14

Identification of Orthologs from Complete Genome Data

More...
OMAi
DAMAFND

Database of Orthologous Groups

More...
OrthoDBi
676681at2

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q49409-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRFKKRFSLD WILKIGTILG LVCLGLFGVI FGSYKLLNDS RLGAVFNGST
60 70 80 90 100
TTTVYFLNHK STNNTSLDPQ QTKPTNGIEN ITNIDSFLDG VEKSYANSLF
110 120 130 140 150
IQGFSSVNIT KNTNDKTASE LDNIDKSWLV NGGLPSVTLT FEQNREQAKT
160 170 180 190 200
RQRKRQVDAQ VRRNAISSVE HNYQLSLETT DGVVLFDSLD NNFINASIRA
210 220 230 240 250
VVPQNTSVNS ALTFEYKLNK NVVTKESLHT DFLDFINSKN LSSSDYNTGN
260 270 280 290 300
GQASVEGNGK FFKQNANGTS SSGNKTLVLW KDKQGALNYV RNIFNVVEGS
310 320 330 340 350
SDYLTFNERE KSLWEFLHAK GSFASGDNLF LNTDANGASP IKKASDITLK
360 370 380 390 400
NLYYIYAAPN HFSAVASNSN DNNNQNNNNN NNSSDVITVS NSADTRKLRS
410 420 430 440 450
ADSSGFSGLF HNYIISEIRT EDPVSKTGDP VKINPTLQSF LDTNNQRIEY
460 470 480 490 500
GGNIKFQVGN FLSSDGTYTP PNFVTAATVK ELLTNPFPTA ATIATAKTSL
510 520 530 540 550
VNAPLANTIT DVSNFASSFI AFGIIVLIAA VLLTLRYKLL GLYKALALGL
560 570 580 590 600
SVVSSLVIFS AVGGVVDVFS FVGIFFVIAI NLINLLNLGE LFLRNIRNNA
610 620 630 640 650
SIIESWKLCL KRSFFANLEF HITWLISALV VIYLSNYQVQ QLANLMAISA
660 670 680 690 700
ITSYFFSYGI SIVLISLFVS SESGANWKLF LYQKDAKALT KTSSNYSLLS
710 720 730 740 750
STSDLNTDFF ITKNQHDFFL KNNWKFLFVW LILLAIGVVM LVLYLVQPNL
760 770 780 790 800
LGEFLAADVE SSNGIIAGIG IVSLLYLAYC LIRYGVAYCL SYLVSFILLC
810 820 830 840 850
SGLFAVMYLT NYLFSIDQST IQLITFVYLF WLFFAAKVSQ TTTWTYFYWF
860 870 880 890 900
KRSLKDKVFI KNLFNDNFNS QWKIDLIESS SLVFIFIIYS GFNFGGIDGN
910 920 930 940 950
FNLVIFYLIA IVGLFDVATA FLPMFCFGLI NGWLSPFNYV HSRLSLKHKK
960 970
HPFKEIDQIE EQLIAGINSF
Length:970
Mass (Da):108,164
Last modified:November 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF106CDFCC9BD44FF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti673 – 678SGANWK → QVQMKA in AAD12390 (PubMed:8253680).Curated6

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L43967 Genomic DNA Translation: AAC71499.1
U02116 Genomic DNA Translation: AAD12390.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F64230

NCBI Reference Sequences

More...
RefSeqi
WP_010869403.1, NC_000908.2

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC71499; AAC71499; MG_277

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mge:MG_277

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA Translation: AAC71499.1
U02116 Genomic DNA Translation: AAD12390.1
PIRiF64230
RefSeqiWP_010869403.1, NC_000908.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi243273.MG_277

Genome annotation databases

EnsemblBacteriaiAAC71499; AAC71499; MG_277
KEGGimge:MG_277

Phylogenomic databases

eggNOGiCOG0841, Bacteria
HOGENOMiCLU_304380_0_0_14
OMAiDAMAFND
OrthoDBi676681at2

Enzyme and pathway databases

BioCyciMGEN243273:G1GJ2-335-MONOMER

Family and domain databases

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiY277_MYCGE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q49409
Secondary accession number(s): Q49253
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 2, 2021
This is version 97 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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