UniProtKB - Q47538 (TAUB_ECOLI)
Protein
Taurine import ATP-binding protein TauB
Gene
tauB
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.UniRule annotation2 Publications
Catalytic activityi
- EC:7.6.2.7UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 34 – 41 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: EcoCyc
GO - Biological processi
- cellular response to sulfur starvation Source: EcoCyc
Keywordsi
Molecular function | Translocase |
Biological process | Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:TAUB-MONOMER MetaCyc:TAUB-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.17.1, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Taurine import ATP-binding protein TauBUniRule annotation (EC:7.6.2.7UniRule annotation) |
Gene namesi | Name:tauBUniRule annotation Synonyms:ssiB, yaiQ Ordered Locus Names:b0366, JW0358 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093007 | 1 – 255 | Taurine import ATP-binding protein TauBAdd BLAST | 255 |
Proteomic databases
PaxDbi | Q47538 |
PRIDEi | Q47538 |
Expressioni
Inductioni
Regulated by CysB in response to sulfate starvation.1 Publication
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (TauB), two transmembrane proteins (TauC) and a solute-binding protein (TauA).
UniRule annotationProtein-protein interaction databases
BioGRIDi | 4261090, 8 interactors |
ComplexPortali | CPX-4312, Taurine ABC transporter complex |
IntActi | Q47538, 4 interactors |
STRINGi | 511145.b0366 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 229 | ABC transporterUniRule annotationAdd BLAST | 228 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. [View classification]UniRule annotation
Phylogenomic databases
eggNOGi | COG4525, Bacteria |
HOGENOMi | CLU_000604_1_22_6 |
InParanoidi | Q47538 |
PhylomeDBi | Q47538 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR015859, ABC_transpr_TauD IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS51250, TAUB, 1 hit |
i Sequence
Sequence statusi: Complete.
Q47538-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLQISHLYAD YGGKPALEDI NLTLESGELL VVLGPSGCGK TTLLNLIAGF
60 70 80 90 100
VPYQHGSIQL AGKRIEGPGA ERGVVFQNEG LLPWRNVQDN VAFGLQLAGI
110 120 130 140 150
EKMQRLEIAH QMLKKVGLEG AEKRYIWQLS GGQRQRVGIA RALAANPQLL
160 170 180 190 200
LLDEPFGALD AFTRDQMQTL LLKLWQETGK QVLLITHDIE EAVFMATELV
210 220 230 240 250
LLSSGPGRVL ERLPLNFARR FVAGESSRSI KSDPQFIAMR EYVLSRVFEQ
REAFS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D85613 Genomic DNA Translation: BAA12839.1 U73857 Genomic DNA Translation: AAB18089.1 U00096 Genomic DNA Translation: AAC73469.1 AP009048 Genomic DNA Translation: BAE76147.1 |
PIRi | S78605, F64764 |
RefSeqi | NP_414900.1, NC_000913.3 WP_000939375.1, NZ_SSZK01000009.1 |
Genome annotation databases
EnsemblBacteriai | AAC73469; AAC73469; b0366 BAE76147; BAE76147; BAE76147 |
GeneIDi | 945027 |
KEGGi | ecj:JW0358 eco:b0366 |
PATRICi | fig|1411691.4.peg.1913 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D85613 Genomic DNA Translation: BAA12839.1 U73857 Genomic DNA Translation: AAB18089.1 U00096 Genomic DNA Translation: AAC73469.1 AP009048 Genomic DNA Translation: BAE76147.1 |
PIRi | S78605, F64764 |
RefSeqi | NP_414900.1, NC_000913.3 WP_000939375.1, NZ_SSZK01000009.1 |
3D structure databases
SMRi | Q47538 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261090, 8 interactors |
ComplexPortali | CPX-4312, Taurine ABC transporter complex |
IntActi | Q47538, 4 interactors |
STRINGi | 511145.b0366 |
Protein family/group databases
TCDBi | 3.A.1.17.1, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | Q47538 |
PRIDEi | Q47538 |
Genome annotation databases
EnsemblBacteriai | AAC73469; AAC73469; b0366 BAE76147; BAE76147; BAE76147 |
GeneIDi | 945027 |
KEGGi | ecj:JW0358 eco:b0366 |
PATRICi | fig|1411691.4.peg.1913 |
Organism-specific databases
EchoBASEi | EB3084 |
Phylogenomic databases
eggNOGi | COG4525, Bacteria |
HOGENOMi | CLU_000604_1_22_6 |
InParanoidi | Q47538 |
PhylomeDBi | Q47538 |
Enzyme and pathway databases
BioCyci | EcoCyc:TAUB-MONOMER MetaCyc:TAUB-MONOMER |
Miscellaneous databases
PROi | PR:Q47538 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR015859, ABC_transpr_TauD IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS51250, TAUB, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TAUB_ECOLI | |
Accessioni | Q47538Primary (citable) accession number: Q47538 Secondary accession number(s): Q2MC59 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | April 7, 2021 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families