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Protein

Protein FdrA

Gene

fdrA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Not known; multicopy suppressor of dominant negative ftsH mutations.

GO - Molecular functioni

GO - Biological processi

  • bacterial-type flagellum-dependent cell motility Source: EcoCyc
  • metabolic process Source: InterPro

Enzyme and pathway databases

BioCyciEcoCyc:G6287-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FdrA
Gene namesi
Name:fdrA
Synonyms:ylbD
Ordered Locus Names:b0518, JW0506
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13399 fdrA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei331 – 351HelicalSequence analysisAdd BLAST21
Transmembranei476 – 496HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000872161 – 555Protein FdrAAdd BLAST555

Proteomic databases

PaxDbiQ47208
PRIDEiQ47208

Interactioni

Protein-protein interaction databases

BioGridi4261244, 129 interactors
IntActiQ47208, 3 interactors
STRINGi316385.ECDH10B_0474

Structurei

Secondary structure

1555
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ47208
SMRiQ47208
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ47208

Family & Domainsi

Sequence similaritiesi

To E.coli YahF and some, to bacterial SucD.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107R1Q Bacteria
COG0074 LUCA
HOGENOMiHOG000117378
KOiK02381
OMAiRAHPMID

Family and domain databases

Gene3Di3.40.50.261, 2 hits
InterProiView protein in InterPro
IPR003781 CoA-bd
IPR005811 CoA_ligase
IPR016102 Succinyl-CoA_synth-like
PfamiView protein in Pfam
PF02629 CoA_binding, 1 hit
PF00549 Ligase_CoA, 1 hit
SUPFAMiSSF52210 SSF52210, 2 hits

Sequencei

Sequence statusi: Complete.

Q47208-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIHAFIKKGC FQDSVSLMII SRKLSESENV DDVSVMMGTP ANKALLDTTG
60 70 80 90 100
FWHDDFNNAT PNDICVAIRS EAADAGIAQA IMQQLEEALK QLAQGSGSSQ
110 120 130 140 150
ALTQVRRWDS ACQKLPDANL ALISVAGEYA AELANQALDR NLNVMMFSDN
160 170 180 190 200
VTLEDEIQLK TRAREKGLLV MGPDCGTSMI AGTPLAFANV MPEGNIGVIG
210 220 230 240 250
ASGTGIQELC SQIALAGEGI THAIGLGGRD LSREVGGISA LTALEMLSAD
260 270 280 290 300
EKSEVLAFVS KPPAEAVRLK IVNAMKATGK PTVALFLGYT PAVARDENVW
310 320 330 340 350
FASSLDEAAR LACLLSRVTA RRNAIAPVSS GFICGLYTGG TLAAEAAGLL
360 370 380 390 400
AGHLGVEADD THQHGMMLDA DSHQIIDLGD DFYTVGRPHP MIDPTLRNQL
410 420 430 440 450
IADLGAKPQV RVLLLDVVIG FGATADPAAS LVSAWQKACA ARLDNQPLYA
460 470 480 490 500
IATVTGTERD PQCRSQQIAT LEDAGIAVVS SLPEATLLAA ALIHPLSPAA
510 520 530 540 550
QQHTPSLLEN VAVINIGLRS FALELQSASK PVVHYQWSPV AGGNKKLARL

LERLQ
Length:555
Mass (Da):58,596
Last modified:November 1, 1996 - v1
Checksum:i732DBF9354E9297C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D42020 Genomic DNA Translation: BAA07638.1
U82664 Genomic DNA Translation: AAB40270.1
U00096 Genomic DNA Translation: AAC73620.1
AP009048 Genomic DNA Translation: BAE76296.1
X05968 Genomic DNA No translation available.
PIRiS60201
RefSeqiNP_415051.1, NC_000913.3
WP_000580829.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73620; AAC73620; b0518
BAE76296; BAE76296; BAE76296
GeneIDi946298
KEGGiecj:JW0506
eco:b0518
PATRICifig|1411691.4.peg.1760

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D42020 Genomic DNA Translation: BAA07638.1
U82664 Genomic DNA Translation: AAB40270.1
U00096 Genomic DNA Translation: AAC73620.1
AP009048 Genomic DNA Translation: BAE76296.1
X05968 Genomic DNA No translation available.
PIRiS60201
RefSeqiNP_415051.1, NC_000913.3
WP_000580829.1, NZ_LN832404.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3DMYX-ray2.07A/B82-555[»]
ProteinModelPortaliQ47208
SMRiQ47208
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261244, 129 interactors
IntActiQ47208, 3 interactors
STRINGi316385.ECDH10B_0474

Proteomic databases

PaxDbiQ47208
PRIDEiQ47208

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73620; AAC73620; b0518
BAE76296; BAE76296; BAE76296
GeneIDi946298
KEGGiecj:JW0506
eco:b0518
PATRICifig|1411691.4.peg.1760

Organism-specific databases

EchoBASEiEB3180
EcoGeneiEG13399 fdrA

Phylogenomic databases

eggNOGiENOG4107R1Q Bacteria
COG0074 LUCA
HOGENOMiHOG000117378
KOiK02381
OMAiRAHPMID

Enzyme and pathway databases

BioCyciEcoCyc:G6287-MONOMER

Miscellaneous databases

EvolutionaryTraceiQ47208
PROiPR:Q47208

Family and domain databases

Gene3Di3.40.50.261, 2 hits
InterProiView protein in InterPro
IPR003781 CoA-bd
IPR005811 CoA_ligase
IPR016102 Succinyl-CoA_synth-like
PfamiView protein in Pfam
PF02629 CoA_binding, 1 hit
PF00549 Ligase_CoA, 1 hit
SUPFAMiSSF52210 SSF52210, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiFDRA_ECOLI
AccessioniPrimary (citable) accession number: Q47208
Secondary accession number(s): Q2MBR0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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