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UniProtKB - Q47155 (DPO4_ECOLI)

Entry version 171 (25 May 2022)
Sequence version 1 (01 Nov 1997)
Previous versions | rss
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Protein

DNA polymerase IV

Gene

dinB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Poorly processive, error-prone DNA polymerase involved in translesion repair and untargeted mutagenesis (PubMed:10488344, PubMed:10801133).

Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by Pol IV. Exhibits no 3'-5' exonuclease (proofreading) activity (PubMed:10488344).

Overexpression of Pol IV results in increased frameshift mutagenesis. It is required for stationary-phase adaptive mutation, which provides the bacterium with flexibility in dealing with environmental stress, enhancing long-term survival and evolutionary fitness. Not seen to be involved in translesion snythesis even when stimulated by the beta slding-clamp and clamp-loading complex, which do however increase non-targeted DNA polymerase efficiency 3,000-fold, may be due to targeting to stalled replication forks on nondamaged DNA (PubMed:10801133, PubMed:16168375).

Involved in translesional synthesis, in conjunction with the beta clamp from PolIII (PubMed:14592985, PubMed:14729336).

1 Publication9 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarityNote: Binds 2 magnesium ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi8MagnesiumBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei13Substrate discriminationBy similarity1
Metal bindingi103MagnesiumBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei104By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase
Biological processDNA damage, DNA repair, DNA replication
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:G6115-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA polymerase IV (EC:2.7.7.7)
Short name:
Pol IV
Alternative name(s):
Translesion synthesis polymerase IV1 Publication
Short name:
TSL polymerase IV
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dinB
Synonyms:dinP
Ordered Locus Names:b0231, JW0221
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi8D → A or H: Loss of function. 1 Publication1
Mutagenesisi49R → A or F: Loss of function. 1 Publication1
Mutagenesisi103D → A or N: Loss of function. 1 Publication1
Mutagenesisi104E → A: Loss of function. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001739121 – 351DNA polymerase IVAdd BLAST351

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q47155

PRoteomics IDEntifications database

More...PRIDEi		Q47155

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By SOS response. A member of the dinB-yafNOP operon (PubMed:12813093). Induced by hydroxyurea (PubMed:20005847).2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

Interacts with beta sliding clamp, which confers increased processivity (PubMed:14592985, PubMed:14729336,PubMed:16168375).

Curated3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4261678, 55 interactors

Protein interaction database and analysis system

More...IntActi		Q47155, 3 interactors

Molecular INTeraction database

More...MINTi		Q47155

STRING: functional protein association networks

More...STRINGi		511145.b0231

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1351
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q47155

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q47155

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q47155

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 185UmuCAdd BLAST182

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The catalytic core consists of fingers, palm and thumb subdomains, but the fingers and thumb subdomains are much smaller than in high-fidelity polymerases; residues from five sequence motifs of the Y-family cluster around an active site cleft that can accommodate DNA and nucleotide substrates with relaxed geometric constraints, with consequently higher rates of misincorporation and low processivity. It lacks the O helices present in high-fidelity DNA polymerases in the fingers domain (By similarity).By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-Y family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0389, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_012348_1_2_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q47155

Identification of Orthologs from Complete Genome Data

More...OMAi		CKPDGLL

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q47155

Family and domain databases

Conserved Domains Database

More...CDDi		cd03586, PolY_Pol_IV_kappa, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.1490.100, 1 hit
3.30.70.270, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01113, DNApol_IV, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR036775, DNA_pol_Y-fam_lit_finger_sf
IPR017961, DNA_pol_Y-fam_little_finger
IPR022880, DNApol_IV
IPR024728, PolY_HhH_motif
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR001126, UmuC

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00817, IMS, 1 hit
PF11799, IMS_C, 1 hit
PF11798, IMS_HHH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF100879, SSF100879, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50173, UMUC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q47155-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRKIIHVDMD CFFAAVEMRD NPALRDIPIA IGGSRERRGV ISTANYPARK 
        60         70         80         90        100
FGVRSAMPTG MALKLCPHLT LLPGRFDAYK EASNHIREIF SRYTSRIEPL 
       110        120        130        140        150
SLDEAYLDVT DSVHCHGSAT LIAQEIRQTI FNELQLTASA GVAPVKFLAK 
       160        170        180        190        200
IASDMNKPNG QFVITPAEVP AFLQTLPLAK IPGVGKVSAA KLEAMGLRTC 
       210        220        230        240        250
GDVQKCDLVM LLKRFGKFGR ILWERSQGID ERDVNSERLR KSVGVERTMA 
       260        270        280        290        300
EDIHHWSECE AIIERLYPEL ERRLAKVKPD LLIARQGVKL KFDDFQQTTQ 
       310        320        330        340        350
EHVWPRLNKA DLIATARKTW DERRGGRGVR LVGLHVTLLD PQMERQLVLG 

L
Length:351
Mass (Da):39,516
Last modified:November 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i74DF44DCA18D405F
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti36 – 38ERR → ARG in strain: ECOR 45B1. 3
Natural varianti124Q → K in strain: ECOR 35D. 1
Natural varianti132N → S in strain: ECOR 34B1 and ECOR 37UG. 1
Natural varianti135Q → H in strain: ECOR 70B1. 1
Natural varianti170P → S in strain: ECOR 37UG. 1
Natural varianti171A → T in strain: ECOR 45B1, ECOR 46D, ECOR 49D and ECOR 50D. 1
Natural varianti176L → F in strain: ECOR 37UG. 1
Natural varianti201G → S in strain: ECOR 59B2. 1
Natural varianti210M → I in strain: ECOR 37UG, ECOR 45B1, ECOR 51B2, ECOR 52B2, ECOR 58B1 and ECOR 70B1. 1
Natural varianti210M → T in strain: ECOR 35D, ECOR 46D, ECOR 49D, ECOR 50D, ECOR 57B2, ECOR 59B2, ECOR 60B2 and ECOR 62B2. 1
Natural varianti225R → C in strain: ECOR 59B2 and ECOR 60B2. 1
Natural varianti310A → S in strain: ECOR 57B2, ECOR 59B2, ECOR 60B2 and ECOR 62B2. 1
Natural varianti321D → N in strain: ECOR 35D. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D38582 Genomic DNA Translation: BAA07593.1
U70214 Genomic DNA Translation: AAB08651.1
U00096 Genomic DNA Translation: AAC73335.1
AP009048 Genomic DNA Translation: BAA77901.1
AF483080 Genomic DNA Translation: AAL91943.1
AF483081 Genomic DNA Translation: AAL91944.1
AF483082 Genomic DNA Translation: AAL91945.1
AF483083 Genomic DNA Translation: AAL91946.1
AF483084 Genomic DNA Translation: AAL91947.1
AF483085 Genomic DNA Translation: AAL91948.1
AF483086 Genomic DNA Translation: AAL91949.1
AF483087 Genomic DNA Translation: AAL91950.1
AF483088 Genomic DNA Translation: AAL91951.1
AF483089 Genomic DNA Translation: AAL91952.1
AF483090 Genomic DNA Translation: AAL91953.1
AF483091 Genomic DNA Translation: AAL91954.1
AF483092 Genomic DNA Translation: AAL91955.1
AF483093 Genomic DNA Translation: AAL91956.1
AF483094 Genomic DNA Translation: AAL91957.1
AF483095 Genomic DNA Translation: AAL91958.1
AF483096 Genomic DNA Translation: AAL91959.1
AF483097 Genomic DNA Translation: AAL91960.1
AF483098 Genomic DNA Translation: AAL91961.1
AF483099 Genomic DNA Translation: AAL91962.1
AF483100 Genomic DNA Translation: AAL91963.1
AF483101 Genomic DNA Translation: AAL91964.1
AF483102 Genomic DNA Translation: AAL91965.1
AF483103 Genomic DNA Translation: AAL91966.1
AF483104 Genomic DNA Translation: AAL91967.1
AF483105 Genomic DNA Translation: AAL91968.1

Protein sequence database of the Protein Information Resource

More...PIRi		H64747

NCBI Reference Sequences

More...RefSeqi		NP_414766.1, NC_000913.3
WP_001226164.1, NZ_SSZK01000050.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC73335; AAC73335; b0231
BAA77901; BAA77901; BAA77901

Database of genes from NCBI RefSeq genomes

More...GeneIDi		944922

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW0221
eco:b0231

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.2052

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38582 Genomic DNA Translation: BAA07593.1
U70214 Genomic DNA Translation: AAB08651.1
U00096 Genomic DNA Translation: AAC73335.1
AP009048 Genomic DNA Translation: BAA77901.1
AF483080 Genomic DNA Translation: AAL91943.1
AF483081 Genomic DNA Translation: AAL91944.1
AF483082 Genomic DNA Translation: AAL91945.1
AF483083 Genomic DNA Translation: AAL91946.1
AF483084 Genomic DNA Translation: AAL91947.1
AF483085 Genomic DNA Translation: AAL91948.1
AF483086 Genomic DNA Translation: AAL91949.1
AF483087 Genomic DNA Translation: AAL91950.1
AF483088 Genomic DNA Translation: AAL91951.1
AF483089 Genomic DNA Translation: AAL91952.1
AF483090 Genomic DNA Translation: AAL91953.1
AF483091 Genomic DNA Translation: AAL91954.1
AF483092 Genomic DNA Translation: AAL91955.1
AF483093 Genomic DNA Translation: AAL91956.1
AF483094 Genomic DNA Translation: AAL91957.1
AF483095 Genomic DNA Translation: AAL91958.1
AF483096 Genomic DNA Translation: AAL91959.1
AF483097 Genomic DNA Translation: AAL91960.1
AF483098 Genomic DNA Translation: AAL91961.1
AF483099 Genomic DNA Translation: AAL91962.1
AF483100 Genomic DNA Translation: AAL91963.1
AF483101 Genomic DNA Translation: AAL91964.1
AF483102 Genomic DNA Translation: AAL91965.1
AF483103 Genomic DNA Translation: AAL91966.1
AF483104 Genomic DNA Translation: AAL91967.1
AF483105 Genomic DNA Translation: AAL91968.1
PIRiH64747
RefSeqiNP_414766.1, NC_000913.3
WP_001226164.1, NZ_SSZK01000050.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OK7X-ray1.65C336-351[»]
1UNNX-ray1.90C/D243-351[»]
4IR1X-ray2.38A/F2-351[»]
4IR9X-ray2.33A/F2-351[»]
4IRCX-ray2.67A/F2-341[»]
4IRDX-ray2.48A/F2-341[»]
4IRKX-ray2.32A/B2-341[»]
4Q43X-ray2.45A/F2-351[»]
4Q44X-ray2.71A/F2-341[»]
4Q45X-ray2.18A/F2-341[»]
4R8UX-ray2.30A2-340[»]
B2-338[»]
5C5JX-ray2.10A/F2-351[»]
5YURX-ray2.04A/F2-351[»]
5YUSX-ray1.94A/F2-351[»]
5YUTX-ray2.15A/F2-351[»]
5YUUX-ray1.89A/F2-351[»]
5YUVX-ray2.06A/F2-351[»]
5YUWX-ray2.12A/F2-351[»]
5YUXX-ray2.04A/F2-351[»]
5YUYX-ray1.74A/F2-351[»]
5YUZX-ray1.83A/F2-351[»]
5YV0X-ray2.09A/F2-351[»]
5YV1X-ray2.09A/F2-351[»]
5YV2X-ray1.90A/F2-351[»]
5YV3X-ray2.03A/F2-351[»]
5YYDX-ray2.05A/F2-351[»]
5YYEX-ray2.33A/F2-351[»]
5ZLVX-ray2.35A/F2-351[»]
6IG1X-ray1.97A/F2-351[»]
6JUPX-ray2.44A/F2-341[»]
6JUQX-ray2.74A/F2-341[»]
AlphaFoldDBiQ47155
SMRiQ47155
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi4261678, 55 interactors
IntActiQ47155, 3 interactors
MINTiQ47155
STRINGi511145.b0231

Proteomic databases

PaxDbiQ47155
PRIDEiQ47155

Genome annotation databases

EnsemblBacteriaiAAC73335; AAC73335; b0231
BAA77901; BAA77901; BAA77901
GeneIDi944922
KEGGiecj:JW0221
eco:b0231
PATRICifig|1411691.4.peg.2052

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB2935

Phylogenomic databases

eggNOGiCOG0389, Bacteria
HOGENOMiCLU_012348_1_2_6
InParanoidiQ47155
OMAiCKPDGLL
PhylomeDBiQ47155

Enzyme and pathway databases

BioCyciEcoCyc:G6115-MONOMER

Miscellaneous databases

EvolutionaryTraceiQ47155

Protein Ontology

More...PROi		PR:Q47155

Family and domain databases

CDDicd03586, PolY_Pol_IV_kappa, 1 hit
Gene3Di3.30.1490.100, 1 hit
3.30.70.270, 1 hit
HAMAPiMF_01113, DNApol_IV, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR036775, DNA_pol_Y-fam_lit_finger_sf
IPR017961, DNA_pol_Y-fam_little_finger
IPR022880, DNApol_IV
IPR024728, PolY_HhH_motif
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR001126, UmuC
PfamiView protein in Pfam
PF00817, IMS, 1 hit
PF11799, IMS_C, 1 hit
PF11798, IMS_HHH, 1 hit
SUPFAMiSSF100879, SSF100879, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS50173, UMUC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDPO4_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q47155
Secondary accession number(s): Q47683
, Q8RJ78, Q8RJ81, Q8RJ86, Q8RJ87, Q8RNI5, Q8RNI6, Q8RNI7, Q8RNI8, Q8RNI9, Q8RNJ0, Q8RNJ1, Q8RNJ2, Q8RNJ3, Q8RNJ4, Q8RNJ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 25, 2022
This is version 171 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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