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Protein

Alkyl hydroperoxide reductase AhpD

Gene

Reut_A2532

Organism
Cupriavidus necator (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.SAAS annotation

Catalytic activityi

2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionAntioxidantSAAS annotation, Oxidoreductase, PeroxidaseSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Alkyl hydroperoxide reductase AhpDSAAS annotation (EC:1.11.1.15SAAS annotation)
Gene namesi
Ordered Locus Names:Reut_A2532Imported
OrganismiCupriavidus necator (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))Imported
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000002697 Componenti: Chromosome 1

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi264198.Reut_A2532

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PRRX-ray2.15A/B/C/D/E/F/G/H/I/J/K/L1-196[»]
ProteinModelPortaliQ46Y90
SMRiQ46Y90
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ46Y90

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 131CMDInterPro annotationAdd BLAST84

Sequence similaritiesi

Belongs to the AhpD family.SAAS annotation

Keywords - Domaini

Redox-active centerSAAS annotation

Phylogenomic databases

eggNOGiENOG4107Q8N Bacteria
COG2128 LUCA
HOGENOMiHOG000219400
OMAiMRPNDEF
OrthoDBiPOG091H0YNQ

Family and domain databases

Gene3Di1.20.1290.10, 1 hit
InterProiView protein in InterPro
IPR029032 AhpD-like
IPR004675 AhpD_core
IPR003779 CMD-like
IPR010195 Uncharacterised_peroxidase-rel
PfamiView protein in Pfam
PF02627 CMD, 1 hit
SUPFAMiSSF69118 SSF69118, 1 hit
TIGRFAMsiTIGR00778 ahpD_dom, 1 hit
TIGR01926 peroxid_rel, 1 hit

Sequencei

Sequence statusi: Complete.

Q46Y90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRPAHPISR YPVPELAALP DDIRQRILEV QDKAGFVPNV FLTLAHRPDE
60 70 80 90 100
FRAFFAYHDA LMLKDGGLTK GEREMIVVAT SAANQCLYCV VAHGAILRIY
110 120 130 140 150
EKKPLVADQV AVNYLKADIP PRQRAMLDFA LKVCKASHEV NEADFEALRE
160 170 180 190
HGFTDEDAWD IAAITAFFGL SNRMANTIGM RPNDEFFLMG RVPKSK
Length:196
Mass (Da):22,018
Last modified:September 13, 2005 - v1
Checksum:i9CC8AB9F5BE48279
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000090 Genomic DNA Translation: AAZ61893.1
RefSeqiWP_011298681.1, NC_007347.1

Genome annotation databases

EnsemblBacteriaiAAZ61893; AAZ61893; Reut_A2532
KEGGireu:Reut_A2532

Similar proteinsi

Entry informationi

Entry nameiQ46Y90_CUPNJ
AccessioniPrimary (citable) accession number: Q46Y90
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: February 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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