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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:Mbar_A0879
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000008156 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000191701 – 245DNA polymerase sliding clampAdd BLAST245

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi269797.Mbar_A0879

Structurei

3D structure databases

ProteinModelPortaliQ46E39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiSDGFDKY
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q46E39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKAAINAEL LKDAVAALAV IVDEVRFKIN PEGISVKAVD PANVAMGIFE
60 70 80 90 100
LGSSAFDEYN ADECEIGVDL NKITDLLGIA DKNDTVRMEL EEENHKLLID
110 120 130 140 150
VGGLSYTLSL LDPSTIRAEP RVPQLELPAK VVLNGADLRR AVKAAEKISD
160 170 180 190 200
HMLMGVSDDT FYMEAKGDTD QVRLEMGRDQ LIDLKAGEAC SLFSLDYLTD
210 220 230 240
IVKPTNKVNE VTLSLGKDFP ILIDFEIANG SGRISYLLAP RIESD
Length:245
Mass (Da):26,759
Last modified:September 13, 2005 - v1
Checksum:i482A51F006E1688F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA Translation: AAZ69853.1
RefSeqiWP_011305902.1, NC_007355.1

Genome annotation databases

EnsemblBacteriaiAAZ69853; AAZ69853; Mbar_A0879
GeneIDi3626187
KEGGimba:Mbar_A0879

Similar proteinsi

Entry informationi

Entry nameiPCNA_METBF
AccessioniPrimary (citable) accession number: Q46E39
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: July 18, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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