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Protein

Beta-lactamase

Gene

imiA

Organism
Enterobacter cloacae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation
Biological processAntibiotic resistanceSAAS annotation

Protein family/group databases

MEROPSiS11.A01

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseSAAS annotation (EC:3.5.2.6SAAS annotation)
Gene namesi
Name:imiAImported
Synonyms:blaIMI-1Imported, imi-1Imported
OrganismiEnterobacter cloacaeImported
Taxonomic identifieri550 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5219

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501410489628 – 292Beta-lactamaseSequence analysisAdd BLAST265

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK19316

Family and domain databases

InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR000871 Beta-lactam_class-A
PRINTSiPR00118 BLACTAMASEA
SUPFAMiSSF56601 SSF56601, 1 hit

Sequencei

Sequence statusi: Complete.

Q46991-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLNVKPSRI AILFSSCLVS ISFFSQANTK GIDEIKDLET DFNGRIGVYA
60 70 80 90 100
LDTGSGKSFS YKANERFPLC SSFKGFLAAA VLKGSQDNQL NLNQIVNYNT
110 120 130 140 150
RSLEFHSPIT TKYKDNGMSL GDMAAAALQY SDNGATNIIL ERYIGGPEGM
160 170 180 190 200
TKFMRSIGDK DFRLDRWELD LNTAIPGDER DTSTPAAVAK SLKTLALGNI
210 220 230 240 250
LNEREKETYQ TWLKGNTTGA ARIRASVPSD WVVGDKTGSC GAYGTANDYA
260 270 280 290
VVWPKNRAPL IISVYTTKNE KEAKHEDKVI AEASRIAIDN LK
Length:292
Mass (Da):32,020
Last modified:November 1, 1996 - v1
Checksum:iA50A4C5DF1645615
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50278 Genomic DNA Translation: AAA93461.1
JX090311 Genomic DNA Translation: AFP32915.1
KR057494 Genomic DNA Translation: AKN35417.1
KP284436 Genomic DNA Translation: AKQ44210.1
RefSeqiWP_053073497.1, NZ_NPNW01000004.1

Genome annotation databases

EnsemblBacteriaiAMJ69946; AMJ69946; AW879_08570
KEGGiag:AAA93461

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50278 Genomic DNA Translation: AAA93461.1
JX090311 Genomic DNA Translation: AFP32915.1
KR057494 Genomic DNA Translation: AKN35417.1
KP284436 Genomic DNA Translation: AKQ44210.1
RefSeqiWP_053073497.1, NZ_NPNW01000004.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

ChEMBLiCHEMBL5219

Protein family/group databases

MEROPSiS11.A01

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAMJ69946; AMJ69946; AW879_08570
KEGGiag:AAA93461

Phylogenomic databases

KOiK19316

Family and domain databases

InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR000871 Beta-lactam_class-A
PRINTSiPR00118 BLACTAMASEA
SUPFAMiSSF56601 SSF56601, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ46991_ENTCL
AccessioniPrimary (citable) accession number: Q46991
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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