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Protein

Probable glucarate transporter

Gene

gudP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Uptake of D-glucarate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:B2789-MONOMER
MetaCyc:B2789-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucarate transporter
Alternative name(s):
D-glucarate permease
Gene namesi
Name:gudP
Synonyms:ygcZ
Ordered Locus Names:b2789, JW2760
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13169 gudP

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 20PeriplasmicSequence analysisAdd BLAST20
Transmembranei21 – 41HelicalSequence analysisAdd BLAST21
Topological domaini42 – 58CytoplasmicSequence analysisAdd BLAST17
Transmembranei59 – 79HelicalSequence analysisAdd BLAST21
Topological domaini80 – 97PeriplasmicSequence analysisAdd BLAST18
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Topological domaini119 – 153CytoplasmicSequence analysisAdd BLAST35
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Topological domaini175 – 176PeriplasmicSequence analysis2
Transmembranei177 – 197HelicalSequence analysisAdd BLAST21
Topological domaini198 – 254CytoplasmicSequence analysisAdd BLAST57
Transmembranei255 – 275HelicalSequence analysisAdd BLAST21
Topological domaini276 – 290PeriplasmicSequence analysisAdd BLAST15
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21
Topological domaini312 – 329CytoplasmicSequence analysisAdd BLAST18
Transmembranei330 – 350HelicalSequence analysisAdd BLAST21
Topological domaini351PeriplasmicSequence analysis1
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Topological domaini373 – 387CytoplasmicSequence analysisAdd BLAST15
Transmembranei388 – 408HelicalSequence analysisAdd BLAST21
Topological domaini409 – 416PeriplasmicSequence analysis8
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Topological domaini438 – 450CytoplasmicSequence analysisAdd BLAST13

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001213851 – 450Probable glucarate transporterAdd BLAST450

Proteomic databases

PaxDbiQ46916
PRIDEiQ46916

Interactioni

Protein-protein interaction databases

BioGridi4263242, 17 interactors
STRINGi316385.ECDH10B_2957

Structurei

3D structure databases

ProteinModelPortaliQ46916
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJB Bacteria
ENOG410XPWC LUCA
HOGENOMiHOG000113642
InParanoidiQ46916
KOiK03535
OMAiYCARVAM
PhylomeDBiQ46916

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR000849 Sugar_P_transporter
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
PIRSFiPIRSF002808 Hexose_phosphate_transp, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

Q46916-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSLSQAASS VEKRTNARYW IVVMLFIVTS FNYGDRATLS IAGSEMAKDI
60 70 80 90 100
GLDPVGMGYV FSAFSWAYVI GQIPGGWLLD RFGSKRVYFW SIFIWSMFTL
110 120 130 140 150
LQGFVDIFSG FGIIVALFTL RFLVGLAEAP SFPGNSRIVA AWFPAQERGT
160 170 180 190 200
AVSIFNSAQY FATVIFAPIM GWLTHEVGWS HVFFFMGGLG IVISFIWLKV
210 220 230 240 250
IHEPNQHPGV NKKELEYIAA GGALINMDQQ NTKVKVPFSV KWGQIKQLLG
260 270 280 290 300
SRMMIGVYIG QYCINALTYF FITWFPVYLV QARGMSILKA GFVASVPAVC
310 320 330 340 350
GFIGGVLGGI ISDWLMRRTG SLNIARKTPI VMGMLLSMVM VFCNYVNVEW
360 370 380 390 400
MIIGFMALAF FGKGIGALGW AVMADTAPKE ISGLSGGLFN MFGNISGIVT
410 420 430 440 450
PIAIGYIVGT TGSFNGALIY VGVHALIAVL SYLVLVGDIK RIELKPVAGQ
Length:450
Mass (Da):49,142
Last modified:November 1, 1996 - v1
Checksum:iE0599FACCB1BB488
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29581 Genomic DNA Translation: AAB40439.1
U00096 Genomic DNA Translation: AAC75831.1
AP009048 Genomic DNA Translation: BAE76861.1
PIRiA65061
RefSeqiNP_417269.1, NC_000913.3
WP_000097072.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75831; AAC75831; b2789
BAE76861; BAE76861; BAE76861
GeneIDi947265
KEGGiecj:JW2760
eco:b2789
PATRICifig|1411691.4.peg.3945

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29581 Genomic DNA Translation: AAB40439.1
U00096 Genomic DNA Translation: AAC75831.1
AP009048 Genomic DNA Translation: BAE76861.1
PIRiA65061
RefSeqiNP_417269.1, NC_000913.3
WP_000097072.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliQ46916
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263242, 17 interactors
STRINGi316385.ECDH10B_2957

Proteomic databases

PaxDbiQ46916
PRIDEiQ46916

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75831; AAC75831; b2789
BAE76861; BAE76861; BAE76861
GeneIDi947265
KEGGiecj:JW2760
eco:b2789
PATRICifig|1411691.4.peg.3945

Organism-specific databases

EchoBASEiEB2961
EcoGeneiEG13169 gudP

Phylogenomic databases

eggNOGiENOG4105DJB Bacteria
ENOG410XPWC LUCA
HOGENOMiHOG000113642
InParanoidiQ46916
KOiK03535
OMAiYCARVAM
PhylomeDBiQ46916

Enzyme and pathway databases

BioCyciEcoCyc:B2789-MONOMER
MetaCyc:B2789-MONOMER

Miscellaneous databases

PROiPR:Q46916

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR000849 Sugar_P_transporter
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
PIRSFiPIRSF002808 Hexose_phosphate_transp, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGUDP_ECOLI
AccessioniPrimary (citable) accession number: Q46916
Secondary accession number(s): Q2MA45
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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