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UniProtKB - Q46889 (OTNK_ECOLI)
Protein
3-oxo-tetronate kinase
Gene
otnK
Organism
Escherichia coli (strain K12)
Status
Functioni
Catalyzes the ATP-dependent phosphorylation of 3-oxo-tetronate to 3-oxo-tetronate 4-phosphate.
By similarityCatalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 258 | ATPBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 360 – 363 | ATPBy similarity | 4 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- kinase activity Source: UniProtKB-KW
GO - Biological processi
- carbohydrate metabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Carbohydrate metabolism |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:G7418-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: 3-oxo-tetronate kinaseBy similarity (EC:2.7.1.217By similarity)Alternative name(s): 3-dehydrotetronate 4-kinaseCurated |
Gene namesi | Name:otnKBy similarity Synonyms:ygbK Ordered Locus Names:b2737, JW2707 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000169313 | 1 – 388 | 3-oxo-tetronate kinaseAdd BLAST | 388 |
Proteomic databases
PaxDbi | Q46889 |
PRIDEi | Q46889 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261444, 20 interactors |
DIPi | DIP-12112N |
IntActi | Q46889, 3 interactors |
STRINGi | 511145.b2737 |
Family & Domainsi
Sequence similaritiesi
Belongs to the four-carbon acid sugar kinase family.Curated
Phylogenomic databases
eggNOGi | COG3395, Bacteria |
HOGENOMi | CLU_029424_1_0_6 |
InParanoidi | Q46889 |
PhylomeDBi | Q46889 |
Family and domain databases
Gene3Di | 3.40.50.10840, 1 hit 3.40.980.20, 1 hit |
InterProi | View protein in InterPro IPR037051, 4-carb_acid_sugar_kinase_N_sf IPR010737, DUF1537 IPR031475, NBD_C IPR042213, NBD_C_sf |
Pfami | View protein in Pfam PF17042, NBD_C, 1 hit PF07005, SBD_N, 1 hit |
i Sequence
Sequence statusi: Complete.
Q46889-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKIGVIADD FTGATDIASF LVENGLPTVQ INGVPTGKMP EAIDALVISL
60 70 80 90 100
KTRSCPVVEA TQQSLAALSW LQQQGCKQIY FKYCSTFDST AKGNIGPVTD
110 120 130 140 150
ALMDALDTPF TVFSPALPVN GRTVYQGYLF VMNQLLAESG MRHHPVNPMT
160 170 180 190 200
DSYLPRLVEA QSTGRCGVVS AHVFEQGVDA VRQELARLQQ EGYRYAVLDA
210 220 230 240 250
LTEHHLEIQG EALRDAPLVT GGSGLAIGLA RQWAQENGNQ ARKAGRPLAG
260 270 280 290 300
RGVVLSGSCS QMTNRQVAHY RQIAPAREVD VARCLSIETL AAYAHELAEW
310 320 330 340 350
VLGQESVLAP LVFATASTDA LAAIQQQYGA QKASQAVETL FSQLAARLAA
360 370 380
EGVTRFIVAG GETSGVVTQS LGIKGFHIGP TISPACRG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U29579 Genomic DNA Translation: AAA69247.1 U00096 Genomic DNA Translation: AAC75779.1 AP009048 Genomic DNA Translation: BAE76814.1 |
PIRi | E65054 |
RefSeqi | NP_417217.1, NC_000913.3 WP_001393459.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC75779; AAC75779; b2737 BAE76814; BAE76814; BAE76814 |
GeneIDi | 947199 |
KEGGi | ecj:JW2707 eco:b2737 |
PATRICi | fig|511145.12.peg.2830 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U29579 Genomic DNA Translation: AAA69247.1 U00096 Genomic DNA Translation: AAC75779.1 AP009048 Genomic DNA Translation: BAE76814.1 |
PIRi | E65054 |
RefSeqi | NP_417217.1, NC_000913.3 WP_001393459.1, NZ_LN832404.1 |
3D structure databases
SMRi | Q46889 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261444, 20 interactors |
DIPi | DIP-12112N |
IntActi | Q46889, 3 interactors |
STRINGi | 511145.b2737 |
Proteomic databases
PaxDbi | Q46889 |
PRIDEi | Q46889 |
Protocols and materials databases
DNASUi | 947199 |
Genome annotation databases
EnsemblBacteriai | AAC75779; AAC75779; b2737 BAE76814; BAE76814; BAE76814 |
GeneIDi | 947199 |
KEGGi | ecj:JW2707 eco:b2737 |
PATRICi | fig|511145.12.peg.2830 |
Organism-specific databases
EchoBASEi | EB2908 |
Phylogenomic databases
eggNOGi | COG3395, Bacteria |
HOGENOMi | CLU_029424_1_0_6 |
InParanoidi | Q46889 |
PhylomeDBi | Q46889 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7418-MONOMER |
Miscellaneous databases
PROi | PR:Q46889 |
Family and domain databases
Gene3Di | 3.40.50.10840, 1 hit 3.40.980.20, 1 hit |
InterProi | View protein in InterPro IPR037051, 4-carb_acid_sugar_kinase_N_sf IPR010737, DUF1537 IPR031475, NBD_C IPR042213, NBD_C_sf |
Pfami | View protein in Pfam PF17042, NBD_C, 1 hit PF07005, SBD_N, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | OTNK_ECOLI | |
Accessioni | Q46889Primary (citable) accession number: Q46889 Secondary accession number(s): Q2MA92 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 125 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families