UniProtKB - Q46812 (SSNA_ECOLI)
Protein
Putative aminohydrolase SsnA
Gene
ssnA
Organism
Escherichia coli (strain K12)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 62 | Zinc; via tele nitrogenSequence analysis | 1 | |
Metal bindingi | 64 | Zinc; via tele nitrogenSequence analysis | 1 | |
Metal bindingi | 227 | Zinc; via tele nitrogenSequence analysis | 1 | |
Metal bindingi | 312 | ZincSequence analysis | 1 |
GO - Molecular functioni
- hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Source: InterPro
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- negative regulation of cell growth Source: CACAO
Keywordsi
Molecular function | Hydrolase |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | EcoCyc:G7498-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ssnA Synonyms:ygfL Ordered Locus Names:b2879, JW2847 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000122303 | 1 – 442 | Putative aminohydrolase SsnAAdd BLAST | 442 |
Proteomic databases
PaxDbi | Q46812 |
PRIDEi | Q46812 |
Expressioni
Inductioni
In stationary phase.
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262326, 69 interactors |
DIPi | DIP-10923N |
IntActi | Q46812, 4 interactors |
STRINGi | 511145.b2879 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0402, Bacteria |
HOGENOMi | CLU_012358_2_6_6 |
InParanoidi | Q46812 |
PhylomeDBi | Q46812 |
Family and domain databases
Gene3Di | 2.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR006680, Amidohydro-rel IPR017700, Aminohydrolase_SsnA IPR011059, Metal-dep_hydrolase_composite IPR032466, Metal_Hydrolase |
Pfami | View protein in Pfam PF01979, Amidohydro_1, 1 hit |
SUPFAMi | SSF51338, SSF51338, 1 hit SSF51556, SSF51556, 1 hit |
TIGRFAMsi | TIGR03314, Se_ssnA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q46812-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLILKNVTAV QLHPAKVQEG VDIAIENDVI VAIGDALTQR YPDASFKEMH
60 70 80 90 100
GRIVMPGIVC SHNHFYSGLS RGIMANIAPC PDFISTLKNL WWRLDRALDE
110 120 130 140 150
ESLYYSGLIC SLEAIKSGCT SVIDHHASPA YIGGSLSTLR DAFLKVGLRA
160 170 180 190 200
MTCFETTDRN NGIKELQEGV EENIRFARLI DEAKKATSEP YLVEAHIGAH
210 220 230 240 250
APFTVPDAGL EMLREAVKAT GRGLHIHAAE DLYDVSYSHH WYGKDLLARL
260 270 280 290 300
AQFDLIDSKT LVAHGLYLSK DDITLLNQRD AFLVHNARSN MNNHVGYNHH
310 320 330 340 350
LSDIRNLALG TDGIGSDMFE EMKFAFFKHR DAGGPLWPDS FAKALTNGNE
360 370 380 390 400
LMSRNFGAKF GLLEAGYKAD LTICDYNSPT PLLADNIAGH IAFGMGSGSV
410 420 430 440
HSVMVNGVMV YEDRQFNFDC DSIYAQARKA AASMWRRMDA LA
Sequence cautioni
The sequence AAA83060 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U28375 Genomic DNA Translation: AAA83060.1 Different initiation. U00096 Genomic DNA Translation: AAC75917.2 AP009048 Genomic DNA Translation: BAE76945.1 D21141 Genomic DNA Translation: BAA04677.1 |
PIRi | G65071 |
RefSeqi | NP_417355.4, NC_000913.3 WP_000906252.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC75917; AAC75917; b2879 BAE76945; BAE76945; BAE76945 |
GeneIDi | 57730312 949072 |
KEGGi | ecj:JW2847 eco:b2879 |
PATRICi | fig|1411691.4.peg.3855 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U28375 Genomic DNA Translation: AAA83060.1 Different initiation. U00096 Genomic DNA Translation: AAC75917.2 AP009048 Genomic DNA Translation: BAE76945.1 D21141 Genomic DNA Translation: BAA04677.1 |
PIRi | G65071 |
RefSeqi | NP_417355.4, NC_000913.3 WP_000906252.1, NZ_LN832404.1 |
3D structure databases
SMRi | Q46812 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262326, 69 interactors |
DIPi | DIP-10923N |
IntActi | Q46812, 4 interactors |
STRINGi | 511145.b2879 |
Proteomic databases
PaxDbi | Q46812 |
PRIDEi | Q46812 |
Protocols and materials databases
DNASUi | 949072 |
Genome annotation databases
EnsemblBacteriai | AAC75917; AAC75917; b2879 BAE76945; BAE76945; BAE76945 |
GeneIDi | 57730312 949072 |
KEGGi | ecj:JW2847 eco:b2879 |
PATRICi | fig|1411691.4.peg.3855 |
Organism-specific databases
EchoBASEi | EB2874 |
Phylogenomic databases
eggNOGi | COG0402, Bacteria |
HOGENOMi | CLU_012358_2_6_6 |
InParanoidi | Q46812 |
PhylomeDBi | Q46812 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7498-MONOMER |
Miscellaneous databases
PROi | PR:Q46812 |
Family and domain databases
Gene3Di | 2.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR006680, Amidohydro-rel IPR017700, Aminohydrolase_SsnA IPR011059, Metal-dep_hydrolase_composite IPR032466, Metal_Hydrolase |
Pfami | View protein in Pfam PF01979, Amidohydro_1, 1 hit |
SUPFAMi | SSF51338, SSF51338, 1 hit SSF51556, SSF51556, 1 hit |
TIGRFAMsi | TIGR03314, Se_ssnA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SSNA_ECOLI | |
Accessioni | Q46812Primary (citable) accession number: Q46812 Secondary accession number(s): Q2M9W1, Q47560 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | May 30, 2000 | |
Last modified: | February 10, 2021 | |
This is version 145 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families