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UniProtKB - Q45R85 (Q45R85_STRFR)

Entry version 81 (19 Jan 2022)
Sequence version 1 (13 Sep 2005)
Previous versions | rss
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Protein
Submitted name:

Peptide synthetase

Gene

lptA

Organism
Streptomyces fradiae (Streptomyces roseoflavus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Peptide synthetaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lptAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces fradiae (Streptomyces roseoflavus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1906 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Actinobacteria › Streptomycetales › Streptomycetaceae › Streptomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1014O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei2091O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3640O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei4738O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei6213O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini979 – 1054CarrierInterPro annotationAdd BLAST76
Domaini2056 – 2130CarrierInterPro annotationAdd BLAST75
Domaini3605 – 3680CarrierInterPro annotationAdd BLAST76
Domaini4703 – 4778CarrierInterPro annotationAdd BLAST76
Domaini6178 – 6252CarrierInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni83 – 102DisorderedSequence analysisAdd BLAST20
Regioni210 – 238DisorderedSequence analysisAdd BLAST29
Regioni1127 – 1151DisorderedSequence analysisAdd BLAST25
Regioni3686 – 3716DisorderedSequence analysisAdd BLAST31
Regioni3871 – 3894DisorderedSequence analysisAdd BLAST24
Regioni6090 – 6123DisorderedSequence analysisAdd BLAST34
Regioni6158 – 6181DisorderedSequence analysisAdd BLAST24
Regioni6248 – 6274DisorderedSequence analysisAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili884 – 904Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1200.10, 4 hits
3.30.300.30, 6 hits
3.30.559.10, 6 hits
3.40.50.12780, 3 hits
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR045851, AMP-bd_C_sf
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, ANL_N_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR013217, Methyltransf_12
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR029063, SAM-dependent_MTases

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00501, AMP-binding, 5 hits
PF13193, AMP-binding_C, 5 hits
PF00668, Condensation, 6 hits
PF08242, Methyltransf_12, 1 hit
PF00550, PP-binding, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00823, PKS_PP, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47336, SSF47336, 5 hits
SSF53335, SSF53335, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01733, AA-adenyl-dom, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00455, AMP_BINDING, 3 hits
PS50075, CARRIER, 5 hits
PS00012, PHOSPHOPANTETHEINE, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q45R85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLESSAHRVA ATSAQTGIWT AQRLRGDDRL YACGLFLELD HVVEEVLSEA 
        60         70         80         90        100
IRRAVADTEA LRTAFREDAD GALEQHVLAR PPSTQTRLFH ADPSGGTPSR 
       110        120        130        140        150
SASLDWMDRQ RAQPWDLASG DTCRHTLIPL GGDRSLLHLR YHHLALDGYG 
       160        170        180        190        200
AALYLDRLAA VYRALRTGHQ PPPCAFAPLA RLVEEDHAYR NSARHRADAN 
       210        220        230        240        250
HWRDRFADLP RPTSLADATT PAAPTTPATP AAPAAPDELR RTVRLSAARS 
       260        270        280        290        300
AALRRASDRS GRPWPVYATA AVAAFLSRLA PGEEVVVGLP VTARVTPAAV 
       310        320        330        340        350
RTPGMLANVV PLRLPVRQGM STAELLELTA AEISTTLRHQ RHRTEDIGRA 
       360        370        380        390        400
LGLHGAPPAT TLVNVMAFAP VLDFGDCRAP VHQLSAGPVE DLVVNLLGTP 
       410        420        430        440        450
GDGGESDGTE LEITVAANPR LHSADAVASL AARLAEFLTH MGQDAEAPLG 
       460        470        480        490        500
RTRLLDAEEE VAAVARGHSP RRDLRARTLP ELFARQVART PDAPAVSSDR 
       510        520        530        540        550
ATWTYAQLDA HAERVARRLA ARGVGPESLV ALAVPRGVEL AALILGIQRA 
       560        570        580        590        600
GGAYLPIDPE YPAERVGFLL RDARPALLVG GTGTEPSAAD CPRVPAEELL 
       610        620        630        640        650
DAGACRAEAD VPPPGSLPVD LPAYVVHTSG STGRPKGVVV THAGIAALAA 
       660        670        680        690        700
EQIERYRLGP GSRVAQLAAL GFDVAVAELV MALASGSCLV LPPHGLAGDE 
       710        720        730        740        750
LASFLRDRRI TTALAPAAVL ATLPPGDLPD LTDLVTGGEQ PPPALIARWA 
       760        770        780        790        800
PGRRMFNVYG PTEATVQATS GRCAADGDRS PDIGNPEAGV DAYVLDAALR 
       810        820        830        840        850
PVPDGVTGEL YLRGRGLARG YLGRPGLTAG RFVADPHTGT GERMYRTGDL 
       860        870        880        890        900
VRRVPGDGRT VLRFVGRADD QVKIRGFRVE PGEVEAALAE LDGVEQALVT 
       910        920        930        940        950
VREERPGDRR LVGYLTPAPG HRGSLDVERL RRVLADRLPA HLVPSLLMEL 
       960        970        980        990       1000
AEIPRTANGK VDRAALPDPA PLAPTAGRAP RDAREEALCA LFAEVLGVEE 
      1010       1020       1030       1040       1050
VGVDLDFFAL GGDSLLAARL ASRIRGRLGK AVTVREVFRS PTVARLAEEL 
      1060       1070       1080       1090       1100
GDGAVPDDHV RPVRPRPERL PLSSAQRRLW FIDELNGASA AYNIPTVLHL 
      1110       1120       1130       1140       1150
EGPLDVPALH AALGDVTDRH ETLRTTLRPP ADDGSAGAPE QHIAPPGGHR 
      1160       1170       1180       1190       1200
PPLPVLDVAP EALAGELRAA AGHVFDLARD LPVRATLYRT GELEHALLLL 
      1210       1220       1230       1240       1250
VHHVAADGAS MGPLIGDLAT AYTARLAGRA PVLPPPEVTY ADFALWERGS 
      1260       1270       1280       1290       1300
RERSAAQAEG IDYWRRALAG LPDHIRLPAD RPRSQEPVRR GGIARFEVPP 
      1310       1320       1330       1340       1350
ALYAGLVELA QGVGATPFMV LQTAIAVLLS RMGAGTDIPL GTPVAGRQDE 
      1360       1370       1380       1390       1400
ALDGLVGCFV NTVVLRTDVS GDPTTTELLA RTRDGDLEAL AHQDVPFDRV 
      1410       1420       1430       1440       1450
VEAVNPVRST SRHPLFQVML ILNGSDQDRH RARFPRLADR VETVEPGETK 
      1460       1470       1480       1490       1500
FDLSWHFTHR DGPDRSLEGA LVHAADLFDD DTAHRLTARL LDVLTAMVDD 
      1510       1520       1530       1540       1550
PARPVGTIDV LSAAEHRLVR AWGTGTPRPP GSRPEPVAAR IAGQAARTPD 
      1560       1570       1580       1590       1600
APAVTEPGRV WSYAELDARA DRVAAALAAR GIGAEDLVAV LLPRGAELVA 
      1610       1620       1630       1640       1650
TLLGILRAGA AYLPLDTGHP ADRNRRALSD SAPALLVTDA GRSRTLRGET 
      1660       1670       1680       1690       1700
GCAALVLGAE DTERELADRA PLPRDGAGLV RPVTGDNAAY TILTSGSTGR 
      1710       1720       1730       1740       1750
PKAVVVTRDA LDAFVDRALD TYGDALGGEA LLHSPVAFDL TVVTLYGPLA 
      1760       1770       1780       1790       1800
AGGRVRVGDL DESGIARWEK ERPAFVKATP SHLALLTEFG GSTAPGTVVL 
      1810       1820       1830       1840       1850
AGEQLIGARL DRWRTRLGAS GTTVLNSYGP TETTVNCLEH RIAPDADVPS 
      1860       1870       1880       1890       1900
GPVPVGRPVP GVRVLLLDDR LRPVAPGVTG ELYVCGPGVA RGYRARPAAT 
      1910       1920       1930       1940       1950
AERFVACPQG RPGERMYRTG DLMRWTADGE LVYEGRADAQ VKVRGFRVEP 
      1960       1970       1980       1990       2000
GEVEAALLGL PGVREAAVTL LEGPEGTEGP EGAPGRVAAP ARLVGYVVGA 
      2010       2020       2030       2040       2050
SEEPAALLER LRVRLPDHMV PAALVDLDAL PLTPNGKLDR RALPAPDFGR 
      2060       2070       2080       2090       2100
HAGRRAPSGP EEEALCALFA DVLGVPEVGA DDSFFTLGGD SIVSIQLVGR 
      2110       2120       2130       2140       2150
ARGAGLHLTV RDVFEHPTAA GLATVVRSAG PDADAERPAP QALAPSGTLP 
      2160       2170       2180       2190       2200
YVPAAARLVA RTGSMRARGA DRFHQSVVLT TPANAAADDV RRVLQTLIDH 
      2210       2220       2230       2240       2250
HGALRLRTAA DRDGSPDGLV ITEPGTVAAA GLLRCRDAAG LQGVALREAV 
      2260       2270       2280       2290       2300
EREAGHARDA LDPSTGAVLR AAWLDRGKDR LGLLVLVAHH LSVDGVSWRI 
      2310       2320       2330       2340       2350
LADDLRQAWT PADAPATTAT LPPEGASLRE WATRIARRAT ETAVTGRLPH 
      2360       2370       2380       2390       2400
WRATLAGLDD PDGDVVALET RLDPEADTHG TAREHAHGLS PDLTDALVRT 
      2410       2420       2430       2440       2450
APAALRADTG ELLLAAYALA ASRTLGDRPV FVAETESHGR QDALLPGVDL 
      2460       2470       2480       2490       2500
TRTVGWFTSV HPVRLRPGAG AERLLKETKE RLRTVPEAGL GHDLLRLGGA 
      2510       2520       2530       2540       2550
ASSPRESGRE LPRPQFGFNY LGRVAVAEAL TDEGTEPAGA WAFAGHSLTA 
      2560       2570       2580       2590       2600
QPPELPLTHE VELTVVLEDG PRGPVLRARW NASARCLTGA RLTALAQEWE 
      2610       2620       2630       2640       2650
KALHELTALA GVAGTAGLIP SETGAGDLDQ DAIEECEAAA DFEVADLLAL 
      2660       2670       2680       2690       2700
APAQEGLLFH STFDDAAEDV YVGQLALEFH GELSGARMRE AAQQVLDRHD 
      2710       2720       2730       2740       2750
VLRAAFLQRR SGEWSQAIAA RTPVPWEEHD LSALAGEERE RRLDALLAGH 
      2760       2770       2780       2790       2800
RTRRFDLARP PLVRFLLVTT AADRHVLAVT NHHLVLDGWS LPLVVRDLMA 
      2810       2820       2830       2840       2850
LYGTDGAALP AVRPYRDYLA WLAGQDADAA HAAWAQALAG LQPSLMAPDA 
      2860       2870       2880       2890       2900
PRDGAAPLAH HRTMDPDVVS RLTAWSRRLG VTLNSVVETA WALLLGRLTG 
      2910       2920       2930       2940       2950
RDDVSFGIAA SGRPTDLPGA GEIVGLLMNT VPVRVTLDPA EPLEALVRRV 
      2960       2970       2980       2990       3000
QREQAALLDH QFLPLAQVQQ SLGAGDLFDT TLVFENYPLA PADGLGDGDG 
      3010       3020       3030       3040       3050
LRLQGARGHD GNHYPLSVTV GPAPDLQLRF IHRPDLFTPP WVEDLAARFE 
      3060       3070       3080       3090       3100
QVLDAMATSG DTPAGRLDIL LPREHDTLLG DWARGEAASA RECPVALFEE 
      3110       3120       3130       3140       3150
QVDRTPDVLA LVEGGDGARL SYAEFDARAN RMARFLIARG LGAEDLVGLV 
      3160       3170       3180       3190       3200
FPRGADLLTG LWGALKAGAA YLPVDVDYPA ERIALLLGDG NPALVLTTSA 
      3210       3220       3230       3240       3250
HAHLVPEAPG RQILCVDLPG PADELARAAE GRVTDSELPR PVGPDTLAYV 
      3260       3270       3280       3290       3300
LYTSGSTGRP KGVAVGRGSL AAHAVRSRDR YPDAAGVSLL HSPVAFDLTV 
      3310       3320       3330       3340       3350
TALFTTLISG GTLLLAELDE HAQDSGVTYV KGTPSHVALL NELPGVLDAT 
      3360       3370       3380       3390       3400
AERPGTLVLG GEPLTGEMLE RWRAHHPQAR VFNDYGPSET SVNCSDLLLE 
      3410       3420       3430       3440       3450
PGAEVPEGLL PIGRPLPGNH MFVLDHLLQP VPVGVVGEIY VSGVGVARGY 
      3460       3470       3480       3490       3500
HGRPGLTAER FLPCPYDAPG ARMYRTGDLG RWRPDGIMEC LGRTDDQVKV 
      3510       3520       3530       3540       3550
RGFRVELGEV EAALAARSDV ARATVVVRED EPGDRRLTGY VVPEGGPDAD 
      3560       3570       3580       3590       3600
FDPAAALRDL AAALPPYMVP AAIVVLSELP RTENGKLDRR ALPAPDYGTA 
      3610       3620       3630       3640       3650
SVGRAPRTAL ETDLCALFAD VLGVPGITLD DDFFALGGHS LLAVRLAGRI 
      3660       3670       3680       3690       3700
RAELGLRLDI RTIFDHRTVA DLLADPQIAA QLTGGLLRGG TPEETPGPRV 
      3710       3720       3730       3740       3750
PARPAATPDP RALPERLPLS PAQRRLWFLN RYDREAGGYH ISVALRLTGD 
      3760       3770       3780       3790       3800
LDVDALHAAL GDLTARHESL RTVFREDEQG PHQVVLDPGA PPAPAVVPAA 
      3810       3820       3830       3840       3850
AHRIDALVRE AVRRPFDLAD DIPLRHTLFT LPDGEHVLLL VIHHIAADGW 
      3860       3870       3880       3890       3900
SMGPLARDLA AAYRARAAGR APDWPAPAAR PAAHPPGQHG DDVDDTVDRR 
      3910       3920       3930       3940       3950
LAHWAEELRG LPDELALPYD RPRPTTPPGY AERVPFRVDA ALYRDVRALA 
      3960       3970       3980       3990       4000
ARHRATPFMV LHAALAALWH RLGAGPDIPV GTPSAGRDRP ETADLVGFLV 
      4010       4020       4030       4040       4050
NTLVLRTDTS GDPAFAELLD RVRETDLRAY AHQDVPFERL VEAVNPARSP 
      4060       4070       4080       4090       4100
SRHPLVQTML TFDNAAHGAL DHLLDLPGVR AELLPTAEGT AHTDIELTFT 
      4110       4120       4130       4140       4150
ETTADTDGDG LDASLRYRPD LFDRTTARAL AERFMALLRT VTREPALRLG 
      4160       4170       4180       4190       4200
QLDVTTAGER RRLADADAAA RARTAATAVA VLPALFAASA HRTPAAPALT 
      4210       4220       4230       4240       4250
DGPATLDYAE LDARSNRLAR ALLGLGVGPE DFVALAVPRS ADLVVAVLAV 
      4260       4270       4280       4290       4300
LKSGAAYLAV DPDHPAERTS YILHDCRPVA VLSTTAVRET LHGTVGEAVG 
      4310       4320       4330       4340       4350
EVPWLLLDEP ATGGATAGHS AAPVTDADRR SPLLPDHPAY TIYTSGSTGR 
      4360       4370       4380       4390       4400
PKGVVVSHAN VSRLLTACRA AVDFGPDDVW TLFHSSAFDF SVWEMWGPLA 
      4410       4420       4430       4440       4450
HGGRLVVVPH DVARSPGDLL DLLGRERVTV LSQTPSAFLQ LLRAESDLGV 
      4460       4470       4480       4490       4500
PPRTTAALRY VVFGGEALDT AQLAPWRGRP VRLVNMYGIT ETTVHVTHLE 
      4510       4520       4530       4540       4550
LDDAAVDRGG SPIGTPLNDL RAHVLDQGLL PVPVGVVGEL YVAGPGLARG 
      4560       4570       4580       4590       4600
YRRRPGLSAT RFVADPFDTG GRMYRTGDLV RRTQDGGLHY VGRSDSQVKL 
      4610       4620       4630       4640       4650
RGYRIEPGEI EAAARRHPDV AQAATAVHGE GPQDRYLVCY VVPAADTDPD 
      4660       4670       4680       4690       4700
PHQVRAHLAD ALPGYMVPAA VVPLTALPLT PNGKLDRAAL PAPDRAAWAT 
      4710       4720       4730       4740       4750
GGAPTGPREE ALCAAFADVL GVQEVSRDAD FFALGGHSLS AVRLISRIRS 
      4760       4770       4780       4790       4800
ALGVEIGIRT LFEAPTPAAL SRRLDTAGTG RPRLLPRRRP DRVPLSSAQR 
      4810       4820       4830       4840       4850
RLWFLGELEG PSATYNIPLA LRLRGRLDVD ALRTALADVV GRHEALRTVF 
      4860       4870       4880       4890       4900
PSEDGAPYQQ VVAAERAAPA LDVVDVTEKE LPAALAEARA HAFTLTEDLP 
      4910       4920       4930       4940       4950
LRAVLLRTGP ADHVLSLVLH HIAGDGWSLA PLARDLSTAY AARREGRAPQ 
      4960       4970       4980       4990       5000
WRPLPVQYAD HTLWKEELLG AADDPESLLA RQLAFWREAL EGAPEQIELP 
      5010       5020       5030       5040       5050
TDRPRPAMES HRGAIHRFTL PASLRDRLRD LAHARRATLF MALQAGLAAL 
      5060       5070       5080       5090       5100
FATLGAGRDI VLGTPVAGRA DEAADDLVGF FVNTLALRTD LGGDPTFEEL 
      5110       5120       5130       5140       5150
LDRVREADLS AFAHQDIPFE QLVEALNPTR SLSRHPVFQV LLALQNNERG 
      5160       5170       5180       5190       5200
EAVMPGLEVT VERPAQAAAK YDLFVNLVES RNEEDGTTAV EGAVEYATDL 
      5210       5220       5230       5240       5250
FDARTVARLT ERYHDLLLAA VEEPTTRLSR MPMLDTAERD RLTAEWGAAA 
      5260       5270       5280       5290       5300
AGPAEDLVAL FRARAAETPG AVAVRGAGDS LTYAQLDERA GRIAAALARH 
      5310       5320       5330       5340       5350
GAGPESRVAV CLPRTADLVA ALLGVLRAGA AYVPLDPEYP DERVAAILAD 
      5360       5370       5380       5390       5400
TRPVALLTTA DCRPAITGAA TAAGGAVLLA ADAAHGAGPV PEPPAPLPDQ 
      5410       5420       5430       5440       5450
AAYVLHTSGS TGRPKGVVVS RGNLANLLAD MRDRLRPTAD DRLVAVTTVS 
      5460       5470       5480       5490       5500
FDIAALELFL PLVTGAGLVL ADRGAARAPE ELAALLTASG ATLLQATPTT 
      5510       5520       5530       5540       5550
WQLLAETAPD ALRGLRKLVG GEALPASLAS RLRELGGELV NVYGPTETTI 
      5560       5570       5580       5590       5600
WSTAAHLDRV TGSAPPIGRA LRGTRAYVLD EWLNPRPENV PGELYLAGAG 
      5610       5620       5630       5640       5650
VARGYLGRGG LTAERFTADP FGAPGSRMYR TGDLVRRRAD GELEFLGRTD 
      5660       5670       5680       5690       5700
HQVKVRGFRI ELGEIETALG AHPHVAGAVV VARAASGAAL VPDAPAPRRL 
      5710       5720       5730       5740       5750
VAYVVPEPHR AAPDDGREQN RLDEWREAYD TLYGSSAPAP LGQDFGIWRS 
      5760       5770       5780       5790       5800
SHDGQPIPLD EMHQWRAATV DRIRALRPTR VLEIGVGTGL LLSELAEDCT 
      5810       5820       5830       5840       5850
AYHGTDLSAR AIETLRAQVD AEPALKERVE LHVRPAHDFD GLRRGFYDTI 
      5860       5870       5880       5890       5900
VLNSVVQYFP DADHLTRVLR GALDLLAPGG RLFVGDVRSL ALLRAFRASV 
      5910       5920       5930       5940       5950
ETGNSAVSET PAAVLAAADR RTAAENELVI APDYFARLRR EAREPLLLDV 
      5960       5970       5980       5990       6000
RIRRGRPYNE LTRYRYDVLL VKQETGAAPS ALPPATELRW TPETGDAGRL 
      6010       6020       6030       6040       6050
AEICAAHPGA LRVTAIPNAR VRRETTALAA LEDGRPVTEV RRLLEQPGDG 
      6060       6070       6080       6090       6100
VDPEDLYDAA TAAGRTAWVT WSADGPPDTV DLVLAPAGGD GVPPVAPPAE 
      6110       6120       6130       6140       6150
LWPGAPAADR PETNDPTAGS HHRELAARLR SHLAERLPDY MVPSAVVVLD 
      6160       6170       6180       6190       6200
ALPLTANGKV DRNALPDPDP AGTDAGRPPR TPREELLCTL FADLLGLGRV 
      6210       6220       6230       6240       6250
GVQDSFFGLG GDSVLSVRLV SRARAHGLPL TTRDVFEHHT AAALAAALDG 
      6260       6270       6280       6290 
REPESEPDGG PPGPDATAAR PITLDELAEL EAEFGTDWEE TQ
Length:6,292
Mass (Da):670,236
Last modified:September 13, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDC2FEB5420CB25A8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DQ118863 Genomic DNA Translation: AAZ23075.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ118863 Genomic DNA Translation: AAZ23075.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

Gene3Di1.10.1200.10, 4 hits
3.30.300.30, 6 hits
3.30.559.10, 6 hits
3.40.50.12780, 3 hits
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR045851, AMP-bd_C_sf
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, ANL_N_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR013217, Methyltransf_12
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR029063, SAM-dependent_MTases
PfamiView protein in Pfam
PF00501, AMP-binding, 5 hits
PF13193, AMP-binding_C, 5 hits
PF00668, Condensation, 6 hits
PF08242, Methyltransf_12, 1 hit
PF00550, PP-binding, 5 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 5 hits
SUPFAMiSSF47336, SSF47336, 5 hits
SSF53335, SSF53335, 1 hit
TIGRFAMsiTIGR01733, AA-adenyl-dom, 5 hits
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 3 hits
PS50075, CARRIER, 5 hits
PS00012, PHOSPHOPANTETHEINE, 5 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ45R85_STRFR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q45R85
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: January 19, 2022
This is version 81 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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