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Entry version 77 (12 Aug 2020)
Sequence version 1 (13 Sep 2005)
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Protein
Submitted name:

Peptide synthetase

Gene

lptA

Organism
Streptomyces fradiae (Streptomyces roseoflavus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Peptide synthetaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lptAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces fradiae (Streptomyces roseoflavus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1906 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1014O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei2091O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3640O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei4738O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei6213O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini979 – 1054CarrierInterPro annotationAdd BLAST76
Domaini2056 – 2130CarrierInterPro annotationAdd BLAST75
Domaini3605 – 3680CarrierInterPro annotationAdd BLAST76
Domaini4703 – 4778CarrierInterPro annotationAdd BLAST76
Domaini6178 – 6252CarrierInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni83 – 102DisorderedSequence analysisAdd BLAST20
Regioni210 – 238DisorderedSequence analysisAdd BLAST29
Regioni1127 – 1151DisorderedSequence analysisAdd BLAST25
Regioni3686 – 3716DisorderedSequence analysisAdd BLAST31
Regioni3871 – 3894DisorderedSequence analysisAdd BLAST24
Regioni6090 – 6123DisorderedSequence analysisAdd BLAST34
Regioni6158 – 6181DisorderedSequence analysisAdd BLAST24
Regioni6248 – 6274DisorderedSequence analysisAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili884 – 904Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 4 hits
3.30.559.10, 6 hits
3.40.50.12780, 5 hits
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR013217, Methyltransf_12
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR029063, SAM-dependent_MTases

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501, AMP-binding, 5 hits
PF13193, AMP-binding_C, 5 hits
PF00668, Condensation, 6 hits
PF08242, Methyltransf_12, 1 hit
PF00550, PP-binding, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00823, PKS_PP, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 5 hits
SSF53335, SSF53335, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733, AA-adenyl-dom, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455, AMP_BINDING, 3 hits
PS50075, CARRIER, 5 hits
PS00012, PHOSPHOPANTETHEINE, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q45R85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLESSAHRVA ATSAQTGIWT AQRLRGDDRL YACGLFLELD HVVEEVLSEA
60 70 80 90 100
IRRAVADTEA LRTAFREDAD GALEQHVLAR PPSTQTRLFH ADPSGGTPSR
110 120 130 140 150
SASLDWMDRQ RAQPWDLASG DTCRHTLIPL GGDRSLLHLR YHHLALDGYG
160 170 180 190 200
AALYLDRLAA VYRALRTGHQ PPPCAFAPLA RLVEEDHAYR NSARHRADAN
210 220 230 240 250
HWRDRFADLP RPTSLADATT PAAPTTPATP AAPAAPDELR RTVRLSAARS
260 270 280 290 300
AALRRASDRS GRPWPVYATA AVAAFLSRLA PGEEVVVGLP VTARVTPAAV
310 320 330 340 350
RTPGMLANVV PLRLPVRQGM STAELLELTA AEISTTLRHQ RHRTEDIGRA
360 370 380 390 400
LGLHGAPPAT TLVNVMAFAP VLDFGDCRAP VHQLSAGPVE DLVVNLLGTP
410 420 430 440 450
GDGGESDGTE LEITVAANPR LHSADAVASL AARLAEFLTH MGQDAEAPLG
460 470 480 490 500
RTRLLDAEEE VAAVARGHSP RRDLRARTLP ELFARQVART PDAPAVSSDR
510 520 530 540 550
ATWTYAQLDA HAERVARRLA ARGVGPESLV ALAVPRGVEL AALILGIQRA
560 570 580 590 600
GGAYLPIDPE YPAERVGFLL RDARPALLVG GTGTEPSAAD CPRVPAEELL
610 620 630 640 650
DAGACRAEAD VPPPGSLPVD LPAYVVHTSG STGRPKGVVV THAGIAALAA
660 670 680 690 700
EQIERYRLGP GSRVAQLAAL GFDVAVAELV MALASGSCLV LPPHGLAGDE
710 720 730 740 750
LASFLRDRRI TTALAPAAVL ATLPPGDLPD LTDLVTGGEQ PPPALIARWA
760 770 780 790 800
PGRRMFNVYG PTEATVQATS GRCAADGDRS PDIGNPEAGV DAYVLDAALR
810 820 830 840 850
PVPDGVTGEL YLRGRGLARG YLGRPGLTAG RFVADPHTGT GERMYRTGDL
860 870 880 890 900
VRRVPGDGRT VLRFVGRADD QVKIRGFRVE PGEVEAALAE LDGVEQALVT
910 920 930 940 950
VREERPGDRR LVGYLTPAPG HRGSLDVERL RRVLADRLPA HLVPSLLMEL
960 970 980 990 1000
AEIPRTANGK VDRAALPDPA PLAPTAGRAP RDAREEALCA LFAEVLGVEE
1010 1020 1030 1040 1050
VGVDLDFFAL GGDSLLAARL ASRIRGRLGK AVTVREVFRS PTVARLAEEL
1060 1070 1080 1090 1100
GDGAVPDDHV RPVRPRPERL PLSSAQRRLW FIDELNGASA AYNIPTVLHL
1110 1120 1130 1140 1150
EGPLDVPALH AALGDVTDRH ETLRTTLRPP ADDGSAGAPE QHIAPPGGHR
1160 1170 1180 1190 1200
PPLPVLDVAP EALAGELRAA AGHVFDLARD LPVRATLYRT GELEHALLLL
1210 1220 1230 1240 1250
VHHVAADGAS MGPLIGDLAT AYTARLAGRA PVLPPPEVTY ADFALWERGS
1260 1270 1280 1290 1300
RERSAAQAEG IDYWRRALAG LPDHIRLPAD RPRSQEPVRR GGIARFEVPP
1310 1320 1330 1340 1350
ALYAGLVELA QGVGATPFMV LQTAIAVLLS RMGAGTDIPL GTPVAGRQDE
1360 1370 1380 1390 1400
ALDGLVGCFV NTVVLRTDVS GDPTTTELLA RTRDGDLEAL AHQDVPFDRV
1410 1420 1430 1440 1450
VEAVNPVRST SRHPLFQVML ILNGSDQDRH RARFPRLADR VETVEPGETK
1460 1470 1480 1490 1500
FDLSWHFTHR DGPDRSLEGA LVHAADLFDD DTAHRLTARL LDVLTAMVDD
1510 1520 1530 1540 1550
PARPVGTIDV LSAAEHRLVR AWGTGTPRPP GSRPEPVAAR IAGQAARTPD
1560 1570 1580 1590 1600
APAVTEPGRV WSYAELDARA DRVAAALAAR GIGAEDLVAV LLPRGAELVA
1610 1620 1630 1640 1650
TLLGILRAGA AYLPLDTGHP ADRNRRALSD SAPALLVTDA GRSRTLRGET
1660 1670 1680 1690 1700
GCAALVLGAE DTERELADRA PLPRDGAGLV RPVTGDNAAY TILTSGSTGR
1710 1720 1730 1740 1750
PKAVVVTRDA LDAFVDRALD TYGDALGGEA LLHSPVAFDL TVVTLYGPLA
1760 1770 1780 1790 1800
AGGRVRVGDL DESGIARWEK ERPAFVKATP SHLALLTEFG GSTAPGTVVL
1810 1820 1830 1840 1850
AGEQLIGARL DRWRTRLGAS GTTVLNSYGP TETTVNCLEH RIAPDADVPS
1860 1870 1880 1890 1900
GPVPVGRPVP GVRVLLLDDR LRPVAPGVTG ELYVCGPGVA RGYRARPAAT
1910 1920 1930 1940 1950
AERFVACPQG RPGERMYRTG DLMRWTADGE LVYEGRADAQ VKVRGFRVEP
1960 1970 1980 1990 2000
GEVEAALLGL PGVREAAVTL LEGPEGTEGP EGAPGRVAAP ARLVGYVVGA
2010 2020 2030 2040 2050
SEEPAALLER LRVRLPDHMV PAALVDLDAL PLTPNGKLDR RALPAPDFGR
2060 2070 2080 2090 2100
HAGRRAPSGP EEEALCALFA DVLGVPEVGA DDSFFTLGGD SIVSIQLVGR
2110 2120 2130 2140 2150
ARGAGLHLTV RDVFEHPTAA GLATVVRSAG PDADAERPAP QALAPSGTLP
2160 2170 2180 2190 2200
YVPAAARLVA RTGSMRARGA DRFHQSVVLT TPANAAADDV RRVLQTLIDH
2210 2220 2230 2240 2250
HGALRLRTAA DRDGSPDGLV ITEPGTVAAA GLLRCRDAAG LQGVALREAV
2260 2270 2280 2290 2300
EREAGHARDA LDPSTGAVLR AAWLDRGKDR LGLLVLVAHH LSVDGVSWRI
2310 2320 2330 2340 2350
LADDLRQAWT PADAPATTAT LPPEGASLRE WATRIARRAT ETAVTGRLPH
2360 2370 2380 2390 2400
WRATLAGLDD PDGDVVALET RLDPEADTHG TAREHAHGLS PDLTDALVRT
2410 2420 2430 2440 2450
APAALRADTG ELLLAAYALA ASRTLGDRPV FVAETESHGR QDALLPGVDL
2460 2470 2480 2490 2500
TRTVGWFTSV HPVRLRPGAG AERLLKETKE RLRTVPEAGL GHDLLRLGGA
2510 2520 2530 2540 2550
ASSPRESGRE LPRPQFGFNY LGRVAVAEAL TDEGTEPAGA WAFAGHSLTA
2560 2570 2580 2590 2600
QPPELPLTHE VELTVVLEDG PRGPVLRARW NASARCLTGA RLTALAQEWE
2610 2620 2630 2640 2650
KALHELTALA GVAGTAGLIP SETGAGDLDQ DAIEECEAAA DFEVADLLAL
2660 2670 2680 2690 2700
APAQEGLLFH STFDDAAEDV YVGQLALEFH GELSGARMRE AAQQVLDRHD
2710 2720 2730 2740 2750
VLRAAFLQRR SGEWSQAIAA RTPVPWEEHD LSALAGEERE RRLDALLAGH
2760 2770 2780 2790 2800
RTRRFDLARP PLVRFLLVTT AADRHVLAVT NHHLVLDGWS LPLVVRDLMA
2810 2820 2830 2840 2850
LYGTDGAALP AVRPYRDYLA WLAGQDADAA HAAWAQALAG LQPSLMAPDA
2860 2870 2880 2890 2900
PRDGAAPLAH HRTMDPDVVS RLTAWSRRLG VTLNSVVETA WALLLGRLTG
2910 2920 2930 2940 2950
RDDVSFGIAA SGRPTDLPGA GEIVGLLMNT VPVRVTLDPA EPLEALVRRV
2960 2970 2980 2990 3000
QREQAALLDH QFLPLAQVQQ SLGAGDLFDT TLVFENYPLA PADGLGDGDG
3010 3020 3030 3040 3050
LRLQGARGHD GNHYPLSVTV GPAPDLQLRF IHRPDLFTPP WVEDLAARFE
3060 3070 3080 3090 3100
QVLDAMATSG DTPAGRLDIL LPREHDTLLG DWARGEAASA RECPVALFEE
3110 3120 3130 3140 3150
QVDRTPDVLA LVEGGDGARL SYAEFDARAN RMARFLIARG LGAEDLVGLV
3160 3170 3180 3190 3200
FPRGADLLTG LWGALKAGAA YLPVDVDYPA ERIALLLGDG NPALVLTTSA
3210 3220 3230 3240 3250
HAHLVPEAPG RQILCVDLPG PADELARAAE GRVTDSELPR PVGPDTLAYV
3260 3270 3280 3290 3300
LYTSGSTGRP KGVAVGRGSL AAHAVRSRDR YPDAAGVSLL HSPVAFDLTV
3310 3320 3330 3340 3350
TALFTTLISG GTLLLAELDE HAQDSGVTYV KGTPSHVALL NELPGVLDAT
3360 3370 3380 3390 3400
AERPGTLVLG GEPLTGEMLE RWRAHHPQAR VFNDYGPSET SVNCSDLLLE
3410 3420 3430 3440 3450
PGAEVPEGLL PIGRPLPGNH MFVLDHLLQP VPVGVVGEIY VSGVGVARGY
3460 3470 3480 3490 3500
HGRPGLTAER FLPCPYDAPG ARMYRTGDLG RWRPDGIMEC LGRTDDQVKV
3510 3520 3530 3540 3550
RGFRVELGEV EAALAARSDV ARATVVVRED EPGDRRLTGY VVPEGGPDAD
3560 3570 3580 3590 3600
FDPAAALRDL AAALPPYMVP AAIVVLSELP RTENGKLDRR ALPAPDYGTA
3610 3620 3630 3640 3650
SVGRAPRTAL ETDLCALFAD VLGVPGITLD DDFFALGGHS LLAVRLAGRI
3660 3670 3680 3690 3700
RAELGLRLDI RTIFDHRTVA DLLADPQIAA QLTGGLLRGG TPEETPGPRV
3710 3720 3730 3740 3750
PARPAATPDP RALPERLPLS PAQRRLWFLN RYDREAGGYH ISVALRLTGD
3760 3770 3780 3790 3800
LDVDALHAAL GDLTARHESL RTVFREDEQG PHQVVLDPGA PPAPAVVPAA
3810 3820 3830 3840 3850
AHRIDALVRE AVRRPFDLAD DIPLRHTLFT LPDGEHVLLL VIHHIAADGW
3860 3870 3880 3890 3900
SMGPLARDLA AAYRARAAGR APDWPAPAAR PAAHPPGQHG DDVDDTVDRR
3910 3920 3930 3940 3950
LAHWAEELRG LPDELALPYD RPRPTTPPGY AERVPFRVDA ALYRDVRALA
3960 3970 3980 3990 4000
ARHRATPFMV LHAALAALWH RLGAGPDIPV GTPSAGRDRP ETADLVGFLV
4010 4020 4030 4040 4050
NTLVLRTDTS GDPAFAELLD RVRETDLRAY AHQDVPFERL VEAVNPARSP
4060 4070 4080 4090 4100
SRHPLVQTML TFDNAAHGAL DHLLDLPGVR AELLPTAEGT AHTDIELTFT
4110 4120 4130 4140 4150
ETTADTDGDG LDASLRYRPD LFDRTTARAL AERFMALLRT VTREPALRLG
4160 4170 4180 4190 4200
QLDVTTAGER RRLADADAAA RARTAATAVA VLPALFAASA HRTPAAPALT
4210 4220 4230 4240 4250
DGPATLDYAE LDARSNRLAR ALLGLGVGPE DFVALAVPRS ADLVVAVLAV
4260 4270 4280 4290 4300
LKSGAAYLAV DPDHPAERTS YILHDCRPVA VLSTTAVRET LHGTVGEAVG
4310 4320 4330 4340 4350
EVPWLLLDEP ATGGATAGHS AAPVTDADRR SPLLPDHPAY TIYTSGSTGR
4360 4370 4380 4390 4400
PKGVVVSHAN VSRLLTACRA AVDFGPDDVW TLFHSSAFDF SVWEMWGPLA
4410 4420 4430 4440 4450
HGGRLVVVPH DVARSPGDLL DLLGRERVTV LSQTPSAFLQ LLRAESDLGV
4460 4470 4480 4490 4500
PPRTTAALRY VVFGGEALDT AQLAPWRGRP VRLVNMYGIT ETTVHVTHLE
4510 4520 4530 4540 4550
LDDAAVDRGG SPIGTPLNDL RAHVLDQGLL PVPVGVVGEL YVAGPGLARG
4560 4570 4580 4590 4600
YRRRPGLSAT RFVADPFDTG GRMYRTGDLV RRTQDGGLHY VGRSDSQVKL
4610 4620 4630 4640 4650
RGYRIEPGEI EAAARRHPDV AQAATAVHGE GPQDRYLVCY VVPAADTDPD
4660 4670 4680 4690 4700
PHQVRAHLAD ALPGYMVPAA VVPLTALPLT PNGKLDRAAL PAPDRAAWAT
4710 4720 4730 4740 4750
GGAPTGPREE ALCAAFADVL GVQEVSRDAD FFALGGHSLS AVRLISRIRS
4760 4770 4780 4790 4800
ALGVEIGIRT LFEAPTPAAL SRRLDTAGTG RPRLLPRRRP DRVPLSSAQR
4810 4820 4830 4840 4850
RLWFLGELEG PSATYNIPLA LRLRGRLDVD ALRTALADVV GRHEALRTVF
4860 4870 4880 4890 4900
PSEDGAPYQQ VVAAERAAPA LDVVDVTEKE LPAALAEARA HAFTLTEDLP
4910 4920 4930 4940 4950
LRAVLLRTGP ADHVLSLVLH HIAGDGWSLA PLARDLSTAY AARREGRAPQ
4960 4970 4980 4990 5000
WRPLPVQYAD HTLWKEELLG AADDPESLLA RQLAFWREAL EGAPEQIELP
5010 5020 5030 5040 5050
TDRPRPAMES HRGAIHRFTL PASLRDRLRD LAHARRATLF MALQAGLAAL
5060 5070 5080 5090 5100
FATLGAGRDI VLGTPVAGRA DEAADDLVGF FVNTLALRTD LGGDPTFEEL
5110 5120 5130 5140 5150
LDRVREADLS AFAHQDIPFE QLVEALNPTR SLSRHPVFQV LLALQNNERG
5160 5170 5180 5190 5200
EAVMPGLEVT VERPAQAAAK YDLFVNLVES RNEEDGTTAV EGAVEYATDL
5210 5220 5230 5240 5250
FDARTVARLT ERYHDLLLAA VEEPTTRLSR MPMLDTAERD RLTAEWGAAA
5260 5270 5280 5290 5300
AGPAEDLVAL FRARAAETPG AVAVRGAGDS LTYAQLDERA GRIAAALARH
5310 5320 5330 5340 5350
GAGPESRVAV CLPRTADLVA ALLGVLRAGA AYVPLDPEYP DERVAAILAD
5360 5370 5380 5390 5400
TRPVALLTTA DCRPAITGAA TAAGGAVLLA ADAAHGAGPV PEPPAPLPDQ
5410 5420 5430 5440 5450
AAYVLHTSGS TGRPKGVVVS RGNLANLLAD MRDRLRPTAD DRLVAVTTVS
5460 5470 5480 5490 5500
FDIAALELFL PLVTGAGLVL ADRGAARAPE ELAALLTASG ATLLQATPTT
5510 5520 5530 5540 5550
WQLLAETAPD ALRGLRKLVG GEALPASLAS RLRELGGELV NVYGPTETTI
5560 5570 5580 5590 5600
WSTAAHLDRV TGSAPPIGRA LRGTRAYVLD EWLNPRPENV PGELYLAGAG
5610 5620 5630 5640 5650
VARGYLGRGG LTAERFTADP FGAPGSRMYR TGDLVRRRAD GELEFLGRTD
5660 5670 5680 5690 5700
HQVKVRGFRI ELGEIETALG AHPHVAGAVV VARAASGAAL VPDAPAPRRL
5710 5720 5730 5740 5750
VAYVVPEPHR AAPDDGREQN RLDEWREAYD TLYGSSAPAP LGQDFGIWRS
5760 5770 5780 5790 5800
SHDGQPIPLD EMHQWRAATV DRIRALRPTR VLEIGVGTGL LLSELAEDCT
5810 5820 5830 5840 5850
AYHGTDLSAR AIETLRAQVD AEPALKERVE LHVRPAHDFD GLRRGFYDTI
5860 5870 5880 5890 5900
VLNSVVQYFP DADHLTRVLR GALDLLAPGG RLFVGDVRSL ALLRAFRASV
5910 5920 5930 5940 5950
ETGNSAVSET PAAVLAAADR RTAAENELVI APDYFARLRR EAREPLLLDV
5960 5970 5980 5990 6000
RIRRGRPYNE LTRYRYDVLL VKQETGAAPS ALPPATELRW TPETGDAGRL
6010 6020 6030 6040 6050
AEICAAHPGA LRVTAIPNAR VRRETTALAA LEDGRPVTEV RRLLEQPGDG
6060 6070 6080 6090 6100
VDPEDLYDAA TAAGRTAWVT WSADGPPDTV DLVLAPAGGD GVPPVAPPAE
6110 6120 6130 6140 6150
LWPGAPAADR PETNDPTAGS HHRELAARLR SHLAERLPDY MVPSAVVVLD
6160 6170 6180 6190 6200
ALPLTANGKV DRNALPDPDP AGTDAGRPPR TPREELLCTL FADLLGLGRV
6210 6220 6230 6240 6250
GVQDSFFGLG GDSVLSVRLV SRARAHGLPL TTRDVFEHHT AAALAAALDG
6260 6270 6280 6290
REPESEPDGG PPGPDATAAR PITLDELAEL EAEFGTDWEE TQ
Length:6,292
Mass (Da):670,236
Last modified:September 13, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDC2FEB5420CB25A8
GO

Sequence databases

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EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
DQ118863 Genomic DNA Translation: AAZ23075.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ118863 Genomic DNA Translation: AAZ23075.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.10.1200.10, 4 hits
3.30.559.10, 6 hits
3.40.50.12780, 5 hits
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR013217, Methyltransf_12
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR029063, SAM-dependent_MTases
PfamiView protein in Pfam
PF00501, AMP-binding, 5 hits
PF13193, AMP-binding_C, 5 hits
PF00668, Condensation, 6 hits
PF08242, Methyltransf_12, 1 hit
PF00550, PP-binding, 5 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 5 hits
SUPFAMiSSF47336, SSF47336, 5 hits
SSF53335, SSF53335, 1 hit
TIGRFAMsiTIGR01733, AA-adenyl-dom, 5 hits
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 3 hits
PS50075, CARRIER, 5 hits
PS00012, PHOSPHOPANTETHEINE, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ45R85_STRFR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q45R85
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: August 12, 2020
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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