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Entry version 70 (12 Aug 2020)
Sequence version 1 (13 Sep 2005)
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Protein
Submitted name:

Peptide synthetase

Gene

lptC

Organism
Streptomyces fradiae (Streptomyces roseoflavus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Peptide synthetaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lptCImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces fradiae (Streptomyces roseoflavus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1906 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1032O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei2568O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3648O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei4713O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini997 – 1071CarrierInterPro annotationAdd BLAST75
Domaini2533 – 2608CarrierInterPro annotationAdd BLAST76
Domaini3613 – 3688CarrierInterPro annotationAdd BLAST76
Domaini4678 – 4752CarrierInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2513 – 2535DisorderedSequence analysisAdd BLAST23
Regioni2825 – 2845DisorderedSequence analysisAdd BLAST21
Regioni3910 – 3930DisorderedSequence analysisAdd BLAST21
Regioni4658 – 4679DisorderedSequence analysisAdd BLAST22
Regioni4743 – 4765DisorderedSequence analysisAdd BLAST23
Regioni5210 – 5230DisorderedSequence analysisAdd BLAST21

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1879 – 1899Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi5213 – 5227Pro-richSequence analysisAdd BLAST15

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 4 hits
3.30.559.10, 6 hits
3.40.50.12780, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR010060, NRPS_synth
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501, AMP-binding, 4 hits
PF13193, AMP-binding_C, 4 hits
PF00668, Condensation, 6 hits
PF00550, PP-binding, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00823, PKS_PP, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 4 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733, AA-adenyl-dom, 4 hits
TIGR01720, NRPS-para261, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455, AMP_BINDING, 2 hits
PS50075, CARRIER, 4 hits
PS00012, PHOSPHOPANTETHEINE, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q45R83-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMLPLSLAQQ RLWFLHTMDG PSSTYNIPTA LRMTGPLDVT ALGEALRDVV
60 70 80 90 100
RRHETLRTVF PDTGDGARQH VLPADGTAVE LAVTRSTEHE LPAALAHEAG
110 120 130 140 150
HAFDLAREVP IRARLFVLGE REHVLCLVIH HIASDGWSRT PLARDLATAY
160 170 180 190 200
AARGAGHAPR WEELPVQYGD YTLWQRELLG SQDDPESLLS RQTAYWKQRL
210 220 230 240 250
AGLPDAIELP LDRPRPPIAG HRGDTVPFTL PPATHERVAA LAARHGATTF
260 270 280 290 300
MVVQAALAGL LSRLGAGTDI PLGTPVAGRT DAALEGLIGF FVNTLVLRTD
310 320 330 340 350
TSGNPTFDEL VERARACALD AYAHQDVPFE RLVETLAPER SLARHPLFQV
360 370 380 390 400
SLSLQHATDH TALLNGLEIA PLDTGWRAAK FDLSFDLLEK RGPDGRPDGI
410 420 430 440 450
AGTVEYSTDV LDAATVRGLG ERLVRLLEAG TAAPEARLLS IDLLSAEERR
460 470 480 490 500
RVLEEFAAEP AADEPAAAEP AADEGLEAVC DTFARQAAAT PEAPAVVGGP
510 520 530 540 550
VALTFAEADA RVSRLARLLI SRGAGPEVRV AVCLDRNALW PTTVLAVLRS
560 570 580 590 600
GAVHVPLDPR SPHERLAAVE RDVAPLLVLA ERATEAAVAD LAAPVLVLDD
610 620 630 640 650
PSTEAAIDAL DPGPVTDADR TAPLLPGHAA YVIHTSGSTG RPKGVTVDHR
660 670 680 690 700
GLSRLLQAHR RVTFSRIRPS AGGPGRAAHV SSFSFDASWD PLLAMVAGHE
710 720 730 740 750
LHMIDEDLRF DPPGVVAYFR DRRIDYVDLT PTYFRSLLDA GLLEEGFPCP
760 770 780 790 800
SLVALGGEAM DGELWERLRA AAPRVTAMNT YGPTETAVDA VVTVLGDLPP
810 820 830 840 850
GTIGRPVPRW RAYVLDAGLR PVPPGVLGEL YLAGPGVARG YLGQHALTAE
860 870 880 890 900
RFVACPFGKP GERMYRTGDL ARWLPDGHLV YVGRGDEQVK IRGFRIEPGE
910 920 930 940 950
VEAALRELEG VAAAAVTVRE DTPGTRRLVG YVVGTPDADD ARLRPAEVLA
960 970 980 990 1000
RLRDRLPDHL VPSAFVRLRE LPVNTSGKLD RAALPAPDPA DFPAGRRPRT
1010 1020 1030 1040 1050
ALEREVCALF AEVLGAGSVG IDDDFFGRGG DSILSIQLVG SARRAGLTFT
1060 1070 1080 1090 1100
VRQVFELRTP AALAAAARRT DAAGDEDPAL AVGPLPLLPV VAETLAAGGP
1110 1120 1130 1140 1150
VHSYNQSVVL ASPPDAAPDD VRDALQALLD RHDALRVHAA PAAGPGRLWD
1160 1170 1180 1190 1200
LRVEEAGTVA AERCLRRIDA TGMSDEELAR AQAAEAVTAR ACLDPLAGAL
1210 1220 1230 1240 1250
VSAVWFDRGD RPGRLVLVIH HLAVDGVSWR ILLGDLREAW RALRAGRRPE
1260 1270 1280 1290 1300
LPRTGTSLRT WATRLTERAT DPAVTAQLDH WTATLADGPA PGSRPLDRTR
1310 1320 1330 1340 1350
DTVATSAVLS GELPASLTTD LLGPAPAAFR AGVNDLLLTA FALAVAHWRG
1360 1370 1380 1390 1400
EEDAPVLVDL ESHGRTEELV PGADLSRTVG WFTSVHPVRL AAGRVTAADL
1410 1420 1430 1440 1450
AERAPAVGDA IKRIKEQLRA VPDGGLGHGL LRHLNPDTAP RLRGLARARF
1460 1470 1480 1490 1500
GFNYLGRFAA EQGAGEDSWP LLGSGPAGQH PDTPLDHEIE VNVVTAEGPD
1510 1520 1530 1540 1550
GPRLITRWTY ATGLLTEEEV RRLTRSWSLA LHAVVGHATA EGAGGLSPSD
1560 1570 1580 1590 1600
VAVPDLGQAE IEQLERRTGT ALEDILPVAP LQEGLLFHSV YDRRALDVYV
1610 1620 1630 1640 1650
GQLAFRLEGE IDQDALRTAA AALLARHTSL RTGFHQRESG QWVQAVARSV
1660 1670 1680 1690 1700
ELPWQFHDLL DPHGAGGAAG AADAGSGRRW EELAAAERVE RFDLTRPPLV
1710 1720 1730 1740 1750
RFLLARTAPE RYQFVITTHH TIVDGWSIPI LLRELLALYG GDPLPPAPGH
1760 1770 1780 1790 1800
RLHADWLAAR DLVAAREAWT RALADTEGPT LLAPGAPRVG EVPRSVRLNL
1810 1820 1830 1840 1850
PEEVSARLLT RAREAGATLN SVVQAVWALV LAQETGRSDV TFGITVSGRP
1860 1870 1880 1890 1900
AELPGAENLV GMLVNKVPLR VRLRPAEPLM ELARRLEREQ LELLEHQHVP
1910 1920 1930 1940 1950
LTTLHRWSGL PELFDTTMVF ENYPAEVTAR QAPFRASGTA SYSRNHYPLT
1960 1970 1980 1990 2000
LVGAMRGTEL TVRVDHRPDL FDEDFARSLG ERVIAALTEA ADHPFVPAGT
2010 2020 2030 2040 2050
LDLLGAEERA RLLEWGTGPA PEDAPRTYVD LFEEQAARTP DAPAVISSDG
2060 2070 2080 2090 2100
VLTYAELDRQ ANGVARWLAG RAGSAGGAEV HIGVLAPRRP EVLAVLLGVL
2110 2120 2130 2140 2150
KSGAAYVPLD EQWPAERLRT VLEDCRPALV LAPTAARSDA ARESGATVLP
2160 2170 2180 2190 2200
VDPAALAAHG PQTPTDAERI RPLTPGAAAY ALYTSGSTGR PKGVVIDHSA
2210 2220 2230 2240 2250
LAAYVGGARR RYPDAAGTSL AHTSLAFDLT VTTLLTPLTA GGAVRLGELD
2260 2270 2280 2290 2300
ETARDAGATL VKATPSHLPL LSELPGALND GGTLILGGEA LTGGRLRPWR
2310 2320 2330 2340 2350
ELHPDAQVVN AYGPTELTVN CTEYRLPKGE PVGEGPVPIG RPFAGVRVHV
2360 2370 2380 2390 2400
LGPGLRPVPA EVPGELYVSG VGVARGYLGR PALTAERFVA CPFGEPGERM
2410 2420 2430 2440 2450
YRTGDLVRWR SDGQLEYVGR SDDQVKLRGF RVETAEVARA LETCPSVGSA
2460 2470 2480 2490 2500
MVVLREDQPG DQRLVGYLVP AAGSGALDKE AVSDAVRAVL PEYMVPSALV
2510 2520 2530 2540 2550
VLEDGPPLTV NGKVDRSALP APEAEPARSA GRAPRGPREE ILCGLFADVL
2560 2570 2580 2590 2600
GVRAVGVDDD FFALGGHSLL AIVVISRIRA LLDVDVAIDA LFEAPTVARL
2610 2620 2630 2640 2650
AAHLDGPGRG HGAVRPAVPR PGRLPLSYAQ LRLWLLHQIE GPSATYTIPL
2660 2670 2680 2690 2700
ALRLTGPLDV AALRAALGDV VARHESLRTV FAEDEHGPHQ IVLAPGDAEP
2710 2720 2730 2740 2750
GLKAVPTTED RLRSDLEAEA ARPFDLGQAP PVHARLFVLD ERTHVLLLAV
2760 2770 2780 2790 2800
HHIAMDGWSV RPLVRDLASA YAARRRGASL DLPALPVQYA DYTLWQHEEL
2810 2820 2830 2840 2850
GSEDDPDSPL AAQLRYWRRT LDGLPQESAP AADRPRPATP SYRGGRVALT
2860 2870 2880 2890 2900
VPPELHGRVV ELAREFRATP FMVVHAALAA LLTRLGAGTD VPIGSPVAGR
2910 2920 2930 2940 2950
VDDALEDLVG FFVNTLVLRT DTSGDPTFGE LLERVRATDL GAYAHQDLPF
2960 2970 2980 2990 3000
ERLVEVLNPE RSLARHPLFQ ILLAFNNGAA PDEGPADRAS DVLVRPETVE
3010 3020 3030 3040 3050
IAAAKFDLSL SFNEDRAADG TAAGMRGVLE YSADLYDEST ARRMAERYLR
3060 3070 3080 3090 3100
LLEAAVAEPR TPLSRIPVLS EAELHDVLVR RNDTGRTRPD SSPLRRFEAQ
3110 3120 3130 3140 3150
AATTPRATAL VVGEERLDYA ELDARAERLA TLLSRSTAGR GGPVAVALPR
3160 3170 3180 3190 3200
GVMLPVALLA VWKAGLHYLP LDPDHPRSRL ADVLADSAPG CVITTTDLAR
3210 3220 3230 3240 3250
RLPPVPAPLL VLDDPATAAR LAATTATALA EDPREQNGEW GEELAYTIYT
3260 3270 3280 3290 3300
SGSTGRPKGV MVTRSAVANF LADMNERLEL GPGDRLLAVT TVSFDIAVLE
3310 3320 3330 3340 3350
LLAPLLTGGT VVLADATTQR DPAAVRSLCA REGVTVIQAT PSWWHAMAVD
3360 3370 3380 3390 3400
GGLDLTALRV LVGGEALPPA LARTLLEPGR APLGDYLLNL YGPTETTVWS
3410 3420 3430 3440 3450
TVARITADSL EAHGGAVPTG TPIARTAAYV LDAALRPVPD GVPGELYLAG
3460 3470 3480 3490 3500
AGLARGYLGR PGMTAERFVA CPFGEPGERM YRTGDLARWR ADGNLEHLGR
3510 3520 3530 3540 3550
TDDQVKVRGF RIELGEVERA LTQAHGVGRA AAAVHPDAAG SARLVGYLVP
3560 3570 3580 3590 3600
AGGSGALDEK AVADAVRAVL PAYMVPSALV VLDGGLPLTA NGKLDRAALP
3610 3620 3630 3640 3650
APEATTGRGP GRAPRGPREE ILCGLFADVL GVPAVGVDDD FFALGGHSLL
3660 3670 3680 3690 3700
ATRLIARVRG TLGVELGVRE VFETPTVAGL AAALSAAGEA GPRLRPADPR
3710 3720 3730 3740 3750
PERLPLSHAQ RRLWFVRQLE GPSATYNVPW ALRLTGPLDV AALRAALGDV
3760 3770 3780 3790 3800
VARHESLRTV FAEDEHGPHQ VVLSADGPAP LSGPVRTDED ALPRLLREAA
3810 3820 3830 3840 3850
DHAFRLDAEP PLRAHLFATA PEDHTLLLVM HHIATDAWSQ RPLIADLAAA
3860 3870 3880 3890 3900
YAARHAGRVP TLPPLPVAYA DYALWQQARL GDEREKDSAL SAQLAYWRDA
3910 3920 3930 3940 3950
LAGSPEELAL PADRPRPAVP SHRGDSVPLT VPPELHGRVV ELAREFRATP
3960 3970 3980 3990 4000
FMVVHAALAA LLTRLGAGTD VPIGSPVAGR VDDALEDLVG FFVNTLVLRT
4010 4020 4030 4040 4050
DTSGDPTFGE LLERVRATDL GAYAHQDLPF ERLVELRDPE RSLARHPLFQ
4060 4070 4080 4090 4100
VSLNYDTAET ARARDAAPEL DGLTVSGRPL GVTTSKFDLT FALTETRAHD
4110 4120 4130 4140 4150
GGPAGLRGAL EYSTDLFDRG TAERLAERFA RVLQAAVAAP GTRLDQIDVL
4160 4170 4180 4190 4200
LPGERALLEG EWSRPEPGPV APTDDARFPD LFEAQAARTP HAPAVRDGDR
4210 4220 4230 4240 4250
ELSYAELNDR ANRLARFLAA RGAGPEDTVA VLLPRGPELI TALVAVQKAG
4260 4270 4280 4290 4300
AAYVPMDAEL PAERIAHMLE NARPVLVLAH TATQDALPEG AGPVVRLDAP
4310 4320 4330 4340 4350
AIEAALAGLD GGDCTDADRR APATHHDPAY VVYTSGSTGT PKGVVVEQRS
4360 4370 4380 4390 4400
LAAFLVRSAA RYRGAAGTAL LHGSPAFDLT VTTLFTPLIA GGCIVVADLD
4410 4420 4430 4440 4450
APERDAPARP DLLKVTPSHL ALLDTIASWA TPAADLVVGG EQLTASRLAR
4460 4470 4480 4490 4500
LRRAHPDMRV FNDYGPTEAT VSCADFVLEP GDAPPTDTVP IGRPLAGHRL
4510 4520 4530 4540 4550
FVLDDRLRPV PANVPGELYV SGVGVARGYL GRPGMTAERF VACPFGEPGE
4560 4570 4580 4590 4600
RMYRTGDLAR RRADGNLEYL GRRDGQVKVR GFRVETGEIE TALLDRPEIG
4610 4620 4630 4640 4650
QAAVVLRGER LLAYVAAPPE RFDPDALRQA LASRLPRYMV PAAFVRLDAL
4660 4670 4680 4690 4700
PLAPGGKLDH RALPEPPAPA DAPHGSRPPR DAWEGVLCEA FGEVLGIAEV
4710 4720 4730 4740 4750
GADDDFFALG GDSIGSIRLV GRVRAAGGRM TVRDIFEQRT PAALAGRSRP
4760 4770 4780 4790 4800
GGPATEVLGG RGTGPVEPTP ISSWLAELGG AVDGYNQSVL LRVPAEADAA
4810 4820 4830 4840 4850
VVTGALQTLL DHHDALRMRA EPEDGHWRME IAEAGAVDAA TVLERVDAAG
4860 4870 4880 4890 4900
ADQGELDRLV RTHCAAARDR LAPQKGSVLR AVWFDGGPRE PGHLALVAHH
4910 4920 4930 4940 4950
LVVDGVSWRI LTADLGSAWQ ALAEGREPHL DPVGTPLRIW ARHLAELAAD
4960 4970 4980 4990 5000
PRRAERCAHW EEQSPRPWET GGLDPALDDR STEEALSLTL PAAATRAVLG
5010 5020 5030 5040 5050
PVPAALGVGV SEVLLGTFAA AVRRRRPAEA ADGVTVDLEG HGREEDVVPG
5060 5070 5080 5090 5100
ADLSRTVGWF TAAHPVRVPA ARPDEDRTGA LRALAAILDR APDAGLGYGL
5110 5120 5130 5140 5150
LRYLNPRTRQ RLAALPAPRY GFNYLGRFGG SGEDRDADDR TSNWSPVAAG
5160 5170 5180 5190 5200
LAGQPAQLPL AHEIEVTAVA VEGPEGPRLI ATWSWAGRLH RERDVRELAE
5210 5220 5230 5240
LWFRELEELA SAEPPPAGPP PLSDPPPLVE LTDTELDQLE AEWKAG
Length:5,246
Mass (Da):560,000
Last modified:September 13, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iABF6C7F657799927
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ118863 Genomic DNA Translation: AAZ23077.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ118863 Genomic DNA Translation: AAZ23077.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.10.1200.10, 4 hits
3.30.559.10, 6 hits
3.40.50.12780, 4 hits
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR010060, NRPS_synth
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
PfamiView protein in Pfam
PF00501, AMP-binding, 4 hits
PF13193, AMP-binding_C, 4 hits
PF00668, Condensation, 6 hits
PF00550, PP-binding, 4 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 4 hits
SUPFAMiSSF47336, SSF47336, 4 hits
TIGRFAMsiTIGR01733, AA-adenyl-dom, 4 hits
TIGR01720, NRPS-para261, 2 hits
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 2 hits
PS50075, CARRIER, 4 hits
PS00012, PHOSPHOPANTETHEINE, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ45R83_STRFR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q45R83
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: August 12, 2020
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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