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UniProtKB - Q43973 (PCAI_ACIAD)
Protein
3-oxoadipate CoA-transferase subunit A
Gene
pcaI
moreOrganism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Status
Functioni
Catalytic activityi
- EC:2.8.3.6
: beta-ketoadipate pathway Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes acetyl-CoA and succinyl-CoA from 3-oxoadipate. This subpathway is part of the pathway beta-ketoadipate pathway, which is itself part of Aromatic compound metabolism.View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA and succinyl-CoA from 3-oxoadipate, the pathway beta-ketoadipate pathway and in Aromatic compound metabolism.
GO - Molecular functioni
- 3-oxoadipate CoA-transferase activity Source: UniProtKB-EC
GO - Biological processi
- beta-ketoadipate pathway Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Transferase |
Biological process | Aromatic hydrocarbons catabolism |
Enzyme and pathway databases
BioCyci | ASP62977:ACIAD_RS06690-MONOMER ASP62977:ACIAD_RS07850-MONOMER |
UniPathwayi | UPA00157;UER00262 |
Names & Taxonomyi
Protein namesi | Recommended name: 3-oxoadipate CoA-transferase subunit A (EC:2.8.3.6)Alternative name(s): Beta-ketoadipate:succinyl-CoA transferase subunit A |
Gene namesi | Name:pcaI Ordered Locus Names:ACIAD1704 AND Name:catI Ordered Locus Names:ACIAD1448 |
Organismi | Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) |
Taxonomic identifieri | 62977 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Moraxellales › Moraxellaceae › Acinetobacter › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000157906 | 1 – 228 | 3-oxoadipate CoA-transferase subunit AAdd BLAST | 228 |
Interactioni
Subunit structurei
Heterodimer.
By similarityProtein-protein interaction databases
STRINGi | 62977.ACIAD1448 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 25 – 31 | CoA-bindingSequence analysis | 7 |
Sequence similaritiesi
Belongs to the 3-oxoacid CoA-transferase subunit A family.Curated
Phylogenomic databases
eggNOGi | COG1788, Bacteria |
HOGENOMi | CLU_019942_2_1_6 |
OMAi | LEYPIHG |
OrthoDBi | 1660857at2 |
Family and domain databases
InterProi | View protein in InterPro IPR012792, 3-oxoacid_CoA-transf_A IPR004165, CoA_trans_fam_I IPR004163, CoA_transf_BS IPR037171, NagB/RpiA_transferase-like |
PANTHERi | PTHR13707, PTHR13707, 1 hit |
Pfami | View protein in Pfam PF01144, CoA_trans, 1 hit |
SMARTi | View protein in SMART SM00882, CoA_trans, 1 hit |
SUPFAMi | SSF100950, SSF100950, 1 hit |
TIGRFAMsi | TIGR02429, pcaI_scoA_fam, 1 hit |
PROSITEi | View protein in PROSITE PS01273, COA_TRANSF_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q43973-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIDKSAATLT EALSQIHDGA TILIGGFGTA GQPAELIDGL IELGRKNLTI
60 70 80 90 100
VSNNAGNGDY GLAKLLKTGA VKKIICSFPR QADSYVFDEL YRAGKIELEI
110 120 130 140 150
VPQGNLACRI QAAGMGLGPI YTPTGFGTLL AEGKPTLNFD GKDYVLENPI
160 170 180 190 200
KADFALIKAY KGDRWGNLVY RKSARNFGPI MAMAANVTIA QVSEVVALGE
210 220
LDPENVVTPG IFVQHVVPVQ STPASAAP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L05770 Genomic DNA Translation: AAC37146.1 AF009224 Genomic DNA Translation: AAC46432.1 CR543861 Genomic DNA Translation: CAG68546.1 CR543861 Genomic DNA Translation: CAG68311.1 |
PIRi | A44570 |
RefSeqi | WP_004925451.1, NC_005966.1 |
Genome annotation databases
EnsemblBacteriai | CAG68311; CAG68311; ACIAD1448 CAG68546; CAG68546; ACIAD1704 |
GeneIDi | 45234091 67510886 |
KEGGi | aci:ACIAD1448 aci:ACIAD1704 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L05770 Genomic DNA Translation: AAC37146.1 AF009224 Genomic DNA Translation: AAC46432.1 CR543861 Genomic DNA Translation: CAG68546.1 CR543861 Genomic DNA Translation: CAG68311.1 |
PIRi | A44570 |
RefSeqi | WP_004925451.1, NC_005966.1 |
3D structure databases
SMRi | Q43973 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 62977.ACIAD1448 |
Genome annotation databases
EnsemblBacteriai | CAG68311; CAG68311; ACIAD1448 CAG68546; CAG68546; ACIAD1704 |
GeneIDi | 45234091 67510886 |
KEGGi | aci:ACIAD1448 aci:ACIAD1704 |
Phylogenomic databases
eggNOGi | COG1788, Bacteria |
HOGENOMi | CLU_019942_2_1_6 |
OMAi | LEYPIHG |
OrthoDBi | 1660857at2 |
Enzyme and pathway databases
UniPathwayi | UPA00157;UER00262 |
BioCyci | ASP62977:ACIAD_RS06690-MONOMER ASP62977:ACIAD_RS07850-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR012792, 3-oxoacid_CoA-transf_A IPR004165, CoA_trans_fam_I IPR004163, CoA_transf_BS IPR037171, NagB/RpiA_transferase-like |
PANTHERi | PTHR13707, PTHR13707, 1 hit |
Pfami | View protein in Pfam PF01144, CoA_trans, 1 hit |
SMARTi | View protein in SMART SM00882, CoA_trans, 1 hit |
SUPFAMi | SSF100950, SSF100950, 1 hit |
TIGRFAMsi | TIGR02429, pcaI_scoA_fam, 1 hit |
PROSITEi | View protein in PROSITE PS01273, COA_TRANSF_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PCAI_ACIAD | |
Accessioni | Q43973Primary (citable) accession number: Q43973 Secondary accession number(s): Q43933 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families