UniProtKB - Q43843 (RPE_SOLTU)
Protein
Ribulose-phosphate 3-epimerase, chloroplastic
Gene
N/A
Organism
Solanum tuberosum (Potato)
Status
Functioni
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.By similarity
Catalytic activityi
- EC:5.1.3.1By similarity
Cofactori
Co2+By similarity, Fe2+By similarity, Mn2+By similarity, Zn2+By similarityNote: Binds 1 divalent metal cation per subunit. Active with Co2+, Fe2+, Mn2+ and Zn2+.By similarity
: Calvin cycle Pathwayi
This protein is involved in the pathway Calvin cycle, which is part of Carbohydrate biosynthesis.By similarityView all proteins of this organism that are known to be involved in the pathway Calvin cycle and in Carbohydrate biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 62 | SubstrateBy similarity | 1 | |
Metal bindingi | 87 | Divalent metal cation; via tele nitrogenBy similarity | 1 | |
Active sitei | 89 | Proton acceptorBy similarity | 1 | |
Metal bindingi | 89 | Divalent metal cationBy similarity | 1 | |
Metal bindingi | 120 | Divalent metal cation; via pros nitrogenBy similarity | 1 | |
Binding sitei | 120 | SubstrateBy similarity | 1 | |
Active sitei | 231 | Proton donorBy similarity | 1 | |
Metal bindingi | 231 | Divalent metal cationBy similarity | 1 |
GO - Molecular functioni
- metal ion binding Source: GO_Central
- ribulose-phosphate 3-epimerase activity Source: UniProtKB
GO - Biological processi
- cellular carbohydrate metabolic process Source: GO_Central
- pentose catabolic process Source: GO_Central
- pentose-phosphate shunt, non-oxidative branch Source: GO_Central
- reductive pentose-phosphate cycle Source: UniProtKB-UniPathway
- response to cold Source: EnsemblPlants
- response to nematode Source: EnsemblPlants
Keywordsi
Molecular function | Isomerase |
Biological process | Calvin cycle, Carbohydrate metabolism, Pentose shunt |
Ligand | Cobalt, Iron, Manganese, Metal-binding, Zinc |
Enzyme and pathway databases
SABIO-RKi | Q43843 |
UniPathwayi | UPA00116 |
Names & Taxonomyi
Protein namesi | Recommended name: Ribulose-phosphate 3-epimerase, chloroplastic (EC:5.1.3.1By similarity)Alternative name(s): Pentose-5-phosphate 3-epimerase Short name: PPE R5P3E Short name: RPE |
Organismi | Solanum tuberosum (Potato) |
Taxonomic identifieri | 4113 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum |
Proteomesi |
|
Subcellular locationi
Chloroplast
- chloroplast thylakoid membrane By similarity
Chloroplast
- chloroplast envelope Source: EnsemblPlants
- chloroplast stroma Source: EnsemblPlants
- chloroplast thylakoid membrane Source: UniProtKB
Cytosol
- cytosol Source: GO_Central
Extracellular region or secreted
- apoplast Source: EnsemblPlants
Other locations
- stromule Source: EnsemblPlants
Keywords - Cellular componenti
Chloroplast, Membrane, Plastid, ThylakoidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | ‹1 – 45 | Chloroplast1 PublicationAdd BLAST | ›45 | |
ChainiPRO_0000025417 | 46 – 280 | Ribulose-phosphate 3-epimerase, chloroplasticAdd BLAST | 235 |
Proteomic databases
PRIDEi | Q43843 |
Expressioni
Tissue specificityi
Highest level of expression in leaves, whereas it is low in roots, tubers, and stems.1 Publication
Gene expression databases
ExpressionAtlasi | Q43843, baseline |
Interactioni
Subunit structurei
Homohexamer.
1 PublicationProtein-protein interaction databases
STRINGi | 4113.PGSC0003DMT400050256 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q43843 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q43843 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 198 – 201 | Substrate bindingBy similarity | 4 | |
Regioni | 231 – 233 | Substrate bindingBy similarity | 3 | |
Regioni | 253 – 254 | Substrate bindingBy similarity | 2 |
Sequence similaritiesi
Belongs to the ribulose-phosphate 3-epimerase family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG3111, Eukaryota |
Family and domain databases
CDDi | cd00429, RPE, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_02227, RPE, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR026019, Ribul_P_3_epim IPR000056, Ribul_P_3_epim-like IPR011060, RibuloseP-bd_barrel |
PANTHERi | PTHR11749, PTHR11749, 1 hit |
Pfami | View protein in Pfam PF00834, Ribul_P_3_epim, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
TIGRFAMsi | TIGR01163, rpe, 1 hit |
PROSITEi | View protein in PROSITE PS01085, RIBUL_P_3_EPIMER_1, 1 hit PS01086, RIBUL_P_3_EPIMER_2, 1 hit |
i Sequence
Sequence statusi: Fragment.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q43843-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
SLGSSTLLQS QISGFGGSQK LQKISFSNPN SLTFTRRRIQ TVVNASSRVD
60 70 80 90 100
KFSKSDIIVS PSILSANFSK LGEQVKAIEQ AGCDWIHVDV MDGRFVPNIT
110 120 130 140 150
IGPLVVDSLR PITDLPLDVH LMIVEPDQRV PDFIKAGADI VSVHCEQSST
160 170 180 190 200
IHLHRTINQI KSLGAKAGVV LNPGTPLTAI EYVLDAVDLV LIMSVNPGFG
210 220 230 240 250
GQSFIESQVK KISDLRKICA ERGLNPWIEV DGGVGPKNAY KVIEAGANAL
260 270 280
VAGSAVFGAP DYAEAIKGIK TSKRPEAVAV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z50098 mRNA Translation: CAA90426.1 |
PIRi | S68407 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z50098 mRNA Translation: CAA90426.1 |
PIRi | S68407 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1RPX | X-ray | 2.30 | A/B/C | 47-276 | [»] | |
SMRi | Q43843 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 4113.PGSC0003DMT400050256 |
Proteomic databases
PRIDEi | Q43843 |
Phylogenomic databases
eggNOGi | KOG3111, Eukaryota |
Enzyme and pathway databases
UniPathwayi | UPA00116 |
SABIO-RKi | Q43843 |
Miscellaneous databases
EvolutionaryTracei | Q43843 |
Gene expression databases
ExpressionAtlasi | Q43843, baseline |
Family and domain databases
CDDi | cd00429, RPE, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_02227, RPE, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR026019, Ribul_P_3_epim IPR000056, Ribul_P_3_epim-like IPR011060, RibuloseP-bd_barrel |
PANTHERi | PTHR11749, PTHR11749, 1 hit |
Pfami | View protein in Pfam PF00834, Ribul_P_3_epim, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
TIGRFAMsi | TIGR01163, rpe, 1 hit |
PROSITEi | View protein in PROSITE PS01085, RIBUL_P_3_EPIMER_1, 1 hit PS01086, RIBUL_P_3_EPIMER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RPE_SOLTU | |
Accessioni | Q43843Primary (citable) accession number: Q43843 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 110 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families