UniProtKB - Q43792 (ACCO_TOBAC)
Protein
1-aminocyclopropane-1-carboxylate oxidase
Gene
ACO
Organism
Nicotiana tabacum (Common tobacco)
Status
Functioni
Catalytic activityi
- 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + ethene + 2 H2O + hydrogen cyanide + L-dehydroascorbateEC:1.14.17.4
Cofactori
Fe cationBy similarity
: ethylene biosynthesis via S-adenosyl-L-methionine Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes ethylene from S-adenosyl-L-methionine.Proteins known to be involved in the 2 steps of the subpathway in this organism are:
- 1-aminocyclopropane-1-carboxylate synthase (ACS1)
- 1-aminocyclopropane-1-carboxylate oxidase (ACO)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes ethylene from S-adenosyl-L-methionine, the pathway ethylene biosynthesis via S-adenosyl-L-methionine and in Alkene biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 177 | IronPROSITE-ProRule annotation | 1 | |
Metal bindingi | 179 | IronPROSITE-ProRule annotation | 1 | |
Metal bindingi | 234 | IronPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- 1-aminocyclopropane-1-carboxylate oxidase activity Source: UniProtKB-EC
- dioxygenase activity Source: GO_Central
- L-ascorbic acid binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- defense response Source: UniProtKB-KW
- ethylene biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Ethylene biosynthesis, Plant defense |
Ligand | Iron, Metal-binding, Vitamin C |
Enzyme and pathway databases
UniPathwayi | UPA00384;UER00563 |
Names & Taxonomyi
Protein namesi | Recommended name: 1-aminocyclopropane-1-carboxylate oxidase (EC:1.14.17.4)Short name: ACC oxidase Alternative name(s): Ethylene-forming enzyme Short name: EFE |
Gene namesi | Name:ACO |
Organismi | Nicotiana tabacum (Common tobacco) |
Taxonomic identifieri | 4097 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000386525 | 1 – 319 | 1-aminocyclopropane-1-carboxylate oxidaseAdd BLAST | 319 |
Expressioni
Inductioni
Up-regulated during the early stage of hypersensitive response.1 Publication
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 152 – 253 | Fe2OG dioxygenasePROSITE-ProRule annotationAdd BLAST | 102 |
Sequence similaritiesi
Belongs to the iron/ascorbate-dependent oxidoreductase family.Curated
Family and domain databases
Gene3Di | 2.60.120.330, 1 hit |
InterProi | View protein in InterPro IPR026992, DIOX_N IPR027443, IPNS-like IPR005123, Oxoglu/Fe-dep_dioxygenase |
Pfami | View protein in Pfam PF03171, 2OG-FeII_Oxy, 1 hit PF14226, DIOX_N, 1 hit |
PROSITEi | View protein in PROSITE PS51471, FE2OG_OXY, 1 hit |
i Sequence
Sequence statusi: Complete.
Q43792-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENFPIINLE KLNGSERADT MEMIKDACEN WGFFELVNHG IPHEVMDTVE
60 70 80 90 100
KMTKGHYKKC MEQRFKELVA SKGLEAVQAE VTDLDWESTF FLRHLPVSNI
110 120 130 140 150
CEVPDLDDQY REVMRDFAKR LEKLAEELLD LLCENLGLEK GYLKKIFYGT
160 170 180 190 200
KGPNFGSKVS NYPPCPKPDL IKGLRAHTDA GGIILLFQDD KVTGLQLLKD
210 220 230 240 250
GQWIDVPPMR LSIVVNLGDQ LEVITNGKYK SVMHRVITQT DGTRMSLASF
260 270 280 290 300
YNPGSDAVIF PAPTLVEKEA EESKAIYPKF VFDDYMKLYA GLKFQAKEPR
310
FEAMIKAMET VKSDPVATA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 119 | K → Q in BAA83466 (Ref. 2) Curated | 1 | |
Sequence conflicti | 151 | K → Q in BAA83466 (Ref. 2) Curated | 1 | |
Sequence conflicti | 157 | S → A in BAA83466 (Ref. 2) Curated | 1 | |
Sequence conflicti | 167 | K → Q in BAA83466 (Ref. 2) Curated | 1 | |
Sequence conflicti | 193 | T → S in BAA83466 (Ref. 2) Curated | 1 | |
Sequence conflicti | 211 | L → H in BAA83466 (Ref. 2) Curated | 1 | |
Sequence conflicti | 285 | Y → N in BAA83466 (Ref. 2) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46349 mRNA Translation: CAA86468.1 AB012857 mRNA Translation: BAA83466.1 |
PIRi | S48811 |
RefSeqi | NP_001312238.1, NM_001325309.1 |
Genome annotation databases
GeneIDi | 107781126 |
KEGGi | nta:107781126 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46349 mRNA Translation: CAA86468.1 AB012857 mRNA Translation: BAA83466.1 |
PIRi | S48811 |
RefSeqi | NP_001312238.1, NM_001325309.1 |
3D structure databases
SMRi | Q43792 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 107781126 |
KEGGi | nta:107781126 |
Enzyme and pathway databases
UniPathwayi | UPA00384;UER00563 |
Family and domain databases
Gene3Di | 2.60.120.330, 1 hit |
InterProi | View protein in InterPro IPR026992, DIOX_N IPR027443, IPNS-like IPR005123, Oxoglu/Fe-dep_dioxygenase |
Pfami | View protein in Pfam PF03171, 2OG-FeII_Oxy, 1 hit PF14226, DIOX_N, 1 hit |
PROSITEi | View protein in PROSITE PS51471, FE2OG_OXY, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ACCO_TOBAC | |
Accessioni | Q43792Primary (citable) accession number: Q43792 Secondary accession number(s): Q9SXL3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 13, 2009 |
Last sequence update: | November 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families