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Entry version 172 (07 Apr 2021)
Sequence version 2 (11 Jul 2002)
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Protein

Glucose-6-phosphate 1-dehydrogenase 1, chloroplastic

Gene

G6PD1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis (PubMed:15634201).

The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division (PubMed:15634201).

1 Publication

Miscellaneous

There are 6 glucose-6-phosphate 1-dehydrogenase genes in A.thaliana.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Regulated by metabolites. Post-translationally inactivated by cysteine-mediated redox modification via the ferredoxin-thioredoxin system in the light and this avoids futile cycles with photosynthetic CO2 fixation.By similarity

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=4.3 µM for NADP1 Publication

    pH dependencei

    Optimum pH is 8.0.1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pentose phosphate pathway

    This protein is involved in step 1 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage).Curated This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei131NADPBy similarity1
    Binding sitei234NADP; via carbonyl oxygenBy similarity1
    Binding sitei234SubstrateBy similarity1
    Binding sitei302SubstrateBy similarity1
    Binding sitei321SubstrateBy similarity1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei326Proton acceptorBy similarity1
    Binding sitei422SubstrateBy similarity1
    Binding sitei427SubstrateBy similarity1
    Binding sitei463SubstrateBy similarity1

    Regions

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi97 – 104NADPBy similarity8

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • glucose-6-phosphate dehydrogenase activity Source: TAIR
    • NADP binding Source: InterPro

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    Biological processCarbohydrate metabolism, Glucose metabolism
    LigandNADP

    Enzyme and pathway databases

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    1.1.1.49, 399

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00115;UER00408

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Glucose-6-phosphate 1-dehydrogenase 1, chloroplasticCurated (EC:1.1.1.491 Publication)
    Short name:
    AtG6PD11 Publication
    Short name:
    G6PDH1Curated
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:G6PD11 Publication
    Synonyms:APG1Curated
    Ordered Locus Names:At5g35790Imported
    ORF Names:MIK22.2Imported, MWP19.3Curated
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

    Organism-specific databases

    Arabidopsis Information Portal

    More...
    Araporti
    AT5G35790

    The Arabidopsis Information Resource

    More...
    TAIRi
    locus:2165154, AT5G35790

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Keywords - Cellular componenti

    Chloroplast, Peroxisome, Plastid

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi149C → S: No effect on the interaction with G6PD4. 1 Publication1
    Mutagenesisi157C → S: No effect on the interaction with G6PD4. 1 Publication1
    Mutagenesisi565K → E: Abolishes targeting to peroxisome. 1 Publication1

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 50ChloroplastSequence analysisAdd BLAST50
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001043551 – 576Glucose-6-phosphate 1-dehydrogenase 1, chloroplasticAdd BLAST526

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi149 ↔ 157Redox modulationBy similarity

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q43727

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q43727

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    248600

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in leaves, stems, buds, flowers and siliques.1 Publication

    <p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

    Increase of activity in the apex linked to the early stages of the transition from vegetative to reproductive growth.

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q43727, baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q43727, AT

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Forms homodimer (By similarity).

    Interacts with G6PD2, G6PD3 and G6PD4 (PubMed:21309870).

    By similarity1 Publication

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGRID)

    More...
    BioGRIDi
    18812, 5 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    Q43727, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    3702.AT5G35790.1

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q43727

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni264 – 268Substrate bindingBy similarity5

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0563, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_013524_2_3_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q43727

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    NIENGWR

    Database of Orthologous Groups

    More...
    OrthoDBi
    383995at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q43727

    Family and domain databases

    HAMAP database of protein families

    More...
    HAMAPi
    MF_00966, G6PD, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR001282, G6P_DH
    IPR019796, G6P_DH_AS
    IPR022675, G6P_DH_C
    IPR022674, G6P_DH_NAD-bd
    IPR036291, NAD(P)-bd_dom_sf

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR23429, PTHR23429, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF02781, G6PD_C, 1 hit
    PF00479, G6PD_N, 1 hit

    PIRSF; a whole-protein classification database

    More...
    PIRSFi
    PIRSF000110, G6PD, 1 hit

    Protein Motif fingerprint database; a protein domain database

    More...
    PRINTSi
    PR00079, G6PDHDRGNASE

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF51735, SSF51735, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR00871, zwf, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00069, G6P_DEHYDROGENASE, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    Q43727-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MATHSMIIPS PSSSSSSLAT AASPFKETLP LFSRSLTFPR KSLFSQVRLR
    60 70 80 90 100
    FFAEKHSQLD TSNGCATNFA SLQDSGDQLT EEHVTKGEST LSITVVGASG
    110 120 130 140 150
    DLAKKKIFPA LFALFYEGCL PQDFSVFGYA RTKLTHEELR DMISSTLTCR
    160 170 180 190 200
    IDQREKCGDK MEQFLKRCFY HSGQYNSEED FAELNKKLKE KEAGKISNRL
    210 220 230 240 250
    YYLSIPPNIF VDVVRCASLR ASSENGWTRV IVEKPFGRDS ESSGELTRCL
    260 270 280 290 300
    KQYLTEEQIF RIDHYLGKEL VENLSVLRFS NLVFEPLWSR NYIRNVQLIF
    310 320 330 340 350
    SEDFGTEGRG GYFDQYGIIR DIMQNHLLQI LALFAMETPV SLDAEDIRSE
    360 370 380 390 400
    KVKVLRSMKP LRLEDVVVGQ YKGHNKGGKT YPGYTDDPTV PNHSLTPTFA
    410 420 430 440 450
    AAAMFINNAR WDGVPFLMKA GKALHTRGAE IRVQFRHVPG NLYKKSFATN
    460 470 480 490 500
    LDNATNELVI RVQPDEGIYL RINNKVPGLG MRLDRSDLNL LYRSRYPREI
    510 520 530 540 550
    PDAYERLLLD AIEGERRLFI RSDELDAAWD LFTPALKELE EKKIIPELYP
    560 570
    YGSRGPVGAH YLASKYNVRW GDLGEA
    Length:576
    Mass (Da):65,428
    Last modified:July 11, 2002 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6559FFCCF76F44DF
    GO

    <p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence CAA59012 differs from that shown. Reason: Frameshift.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti110A → D in CAA59012 (Ref. 6) Curated1
    Sequence conflicti205 – 213IPPNIFVDV → STPKLLVDE in CAA04696 (PubMed:10437832).Curated9
    Sequence conflicti297Q → E in CAA59012 (Ref. 6) Curated1
    Sequence conflicti383G → A in CAA59012 (Ref. 6) Curated1
    Sequence conflicti485 – 486RS → PR in CAA04696 (PubMed:10437832).Curated2
    Sequence conflicti514G → A in CAA04696 (PubMed:10437832).Curated1
    Sequence conflicti530D → E in CAA04696 (PubMed:10437832).Curated1
    Sequence conflicti539L → R in CAA04696 (PubMed:10437832).Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AJ001359 mRNA Translation: CAA04696.1
    AB005236 Genomic DNA Translation: BAB09918.1
    CP002688 Genomic DNA Translation: AED94018.1
    AY099561 mRNA Translation: AAM20413.1
    BT002133 mRNA Translation: AAN72144.1
    AY086213 mRNA Translation: AAM64291.1
    X84230 mRNA Translation: CAA59012.1 Frameshift.

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_198428.1, NM_122970.6

    Genome annotation databases

    Ensembl plant genome annotation project

    More...
    EnsemblPlantsi
    AT5G35790.1; AT5G35790.1; AT5G35790

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    833559

    Gramene; a comparative resource for plants

    More...
    Gramenei
    AT5G35790.1; AT5G35790.1; AT5G35790

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    ath:AT5G35790

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AJ001359 mRNA Translation: CAA04696.1
    AB005236 Genomic DNA Translation: BAB09918.1
    CP002688 Genomic DNA Translation: AED94018.1
    AY099561 mRNA Translation: AAM20413.1
    BT002133 mRNA Translation: AAN72144.1
    AY086213 mRNA Translation: AAM64291.1
    X84230 mRNA Translation: CAA59012.1 Frameshift.
    RefSeqiNP_198428.1, NM_122970.6

    3D structure databases

    SMRiQ43727
    ModBaseiSearch...

    Protein-protein interaction databases

    BioGRIDi18812, 5 interactors
    IntActiQ43727, 1 interactor
    STRINGi3702.AT5G35790.1

    Proteomic databases

    PaxDbiQ43727
    PRIDEiQ43727
    ProteomicsDBi248600

    Genome annotation databases

    EnsemblPlantsiAT5G35790.1; AT5G35790.1; AT5G35790
    GeneIDi833559
    GrameneiAT5G35790.1; AT5G35790.1; AT5G35790
    KEGGiath:AT5G35790

    Organism-specific databases

    AraportiAT5G35790
    TAIRilocus:2165154, AT5G35790

    Phylogenomic databases

    eggNOGiKOG0563, Eukaryota
    HOGENOMiCLU_013524_2_3_1
    InParanoidiQ43727
    OMAiNIENGWR
    OrthoDBi383995at2759
    PhylomeDBiQ43727

    Enzyme and pathway databases

    UniPathwayiUPA00115;UER00408
    BRENDAi1.1.1.49, 399

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:Q43727

    Gene expression databases

    ExpressionAtlasiQ43727, baseline and differential
    GenevisibleiQ43727, AT

    Family and domain databases

    HAMAPiMF_00966, G6PD, 1 hit
    InterProiView protein in InterPro
    IPR001282, G6P_DH
    IPR019796, G6P_DH_AS
    IPR022675, G6P_DH_C
    IPR022674, G6P_DH_NAD-bd
    IPR036291, NAD(P)-bd_dom_sf
    PANTHERiPTHR23429, PTHR23429, 1 hit
    PfamiView protein in Pfam
    PF02781, G6PD_C, 1 hit
    PF00479, G6PD_N, 1 hit
    PIRSFiPIRSF000110, G6PD, 1 hit
    PRINTSiPR00079, G6PDHDRGNASE
    SUPFAMiSSF51735, SSF51735, 1 hit
    TIGRFAMsiTIGR00871, zwf, 1 hit
    PROSITEiView protein in PROSITE
    PS00069, G6P_DEHYDROGENASE, 1 hit

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG6PD1_ARATH
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q43727
    Secondary accession number(s): O65577, Q9FFM5
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: July 11, 2002
    Last modified: April 7, 2021
    This is version 172 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families
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