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Protein

Cryptochrome-1

Gene

CRY1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Photoreceptor that mediates primarily blue light inhibition of hypocotyl elongation and photoperiodic control of floral initiation, and regulates other light responses, including circadian rhythms, tropic growth, stomata opening, guard cell development, root development, bacterial and viral pathogen responses, abiotic stress responses, cell cycles, programmed cell death, apical dominance, fruit and ovule development, seed dormancy, and magnetoreception. Photoexcited cryptochromes interact with signaling partner proteins to alter gene expression at both transcriptional and post-translational levels and, consequently, regulate the corresponding metabolic and developmental programs (PubMed:21841916). Blue-light absorbing flavoprotein that activates reversible flavin photoreduction via an electron transport chain comprising a tryptophan triad (W-324, W-377 and W-400), accompanied by a large conformational change upon photoexcitation, or via an alternative electron transport that involves small metabolites, including NADPH, NADH, and ATP. The half-life of the activated signaling state is about 5 minutes (PubMed:26313597, PubMed:25157750, PubMed:23398192, PubMed:21875594, PubMed:21467031). Also involved in the detection of blue/green ratio in light (shade under leaf canopies) and subsequent adaptations on plant growth and development (PubMed:20668058). In darkness, the dark reoxidation of flavin occurs and leads to inactivated state (PubMed:21467031, PubMed:23398192). Perceives low blue light (LBL) and responds by directly contacting two bHLH transcription factors, PIF4 and PIF5, at chromatin on E-box variant 5'-CA[CT]GTG-3' to promote their activity and stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation and hyponastic growth in low blue light) (PubMed:26724867, PubMed:19558423). When activated by high-intensity blue light, catalyzes direct enzymatic conversion of molecular oxygen O2 to reactive oxygen species (ROS) and hydrogen peroxide H2O2 in vitro. ROS accumulation upon activation by blue light leads to cell death in protoplasts (PubMed:25728686). Seems essential for blue-light-triggered and singlet oxygen-mediated programmed cell death (PCD) (PubMed:17075038). Required for the induction of nuclear genes encoding photoprotective components by GATA24 and GATA28 in extreme light intensities that exceed the electron utilization capacity of the chloroplast (PubMed:22786870). Involved in shortening the circadian clock period, especially at 27 degrees Celsius, in blue light (BL) and required to maintain clock genes expression rhythm (PubMed:23511208). Mediates blue light-induced gene expression and hypocotyl elongation through the inhibition of COP1-mediated degradation of the transcription factors BIT1 and HY5 and via the activation of anion channels at the plasma membrane, probably via auxin signaling (PubMed:21511872, PubMed:21511871, PubMed:16093319, PubMed:18397371, PubMed:12324610, PubMed:8528277, PubMed:9765547, PubMed:25721730). Required for the hypocotyl hook formation in darkness (PubMed:22855128). Involved in blue light-dependent stomatal opening, CHS gene expression, transpiration, inhibition of stem growth and increase of root growth, probably by regulating abscisic acid (ABA) (PubMed:22147516, PubMed:16093319, PubMed:16703358, PubMed:7756321, PubMed:9565033). Prevents lateral roots growth by inhibiting auxin transport (PubMed:20133010). Necessary for shade avoidance syndrome (SAS), characterized by leaf hyponasty and reduced lamina/petiole ratio, when exposed to blue light attenuation (PubMed:21457375). Together with phototropins, involved in phototropism regulation by various blue light fluence; blue light attenuates phototropism in high fluence rates (100 µmol.m-2.s-1) but enhances phototropism in low fluence rates (<1.0 µmol.m-2.s-1) (PubMed:12857830). Required for blue/UV-A wavelengths-mediated inhibition of explants shoot regeneration in vitro (e.g. new shoot apical meristems regeneration from excised cotyledons) (PubMed:22681544). Modulates anthocyanin accumulation in a PHYA-dependent manner in far-red-light. Acts as a PHYA/PHYB-dependent modulator of chlorophyll accumulation in red light. Contributes to most blue light deetiolation responses (PubMed:9733523, PubMed:8528277). May act as a chemical magnetoreceptor, via magnetically sensitive kinetics and quantum yields of photo-induced flavin / tryptophan radical pairs (PubMed:22421133). The effect of near-null magnetic field on flowering is altered by changes of blue light cycle and intensity in a CRY1/CRY2-dependent manner (PubMed:26095447). Involved in the strigolactone signaling that regulates hypocotyl growth in response to blue light (PubMed:24126495). Modulates temperature-dependent growth and physiology maintenance, especially at warm ambient temperatures, via HFR1-dependent activity (PubMed:21265897).1 Publication34 Publications
Implicated in promoting R protein-mediated resistance to Pseudomonas syringae pv. tomato (Pst.) DC3000 under continuous light conditions. Promotes systemic acquired resistance (SAR) and PR gene expression triggered by P. syringae.1 Publication

Caution

Was originally thought to be a DNA photolyase.1 Publication

Cofactori

Protein has several cofactor binding sites:

Activity regulationi

Light exposure induces a conformational change in the C-terminal domain CCT1 required for activity.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei235FADCombined sources1 Publication1
Metal bindingi238Magnesium 1; via carbonyl oxygenCombined sources1 Publication1
Binding sitei239ATPCombined sources1 Publication1
Metal bindingi241Magnesium 2; via carbonyl oxygenCombined sources1 Publication1
Metal bindingi244Magnesium 2Combined sources1 Publication1
Metal bindingi246Magnesium 1Combined sources1 Publication1
Metal bindingi246Magnesium 2Combined sources1 Publication1
Binding sitei293FAD; via carbonyl oxygenCombined sources1 Publication1
Sitei324Involved in electron transfer from the protein surface to the FAD cofactor1 Publication1 Publication1
Metal bindingi358Magnesium 1; via tele nitrogenCombined sources1 Publication1
Binding sitei359FADCombined sources1 Publication1
Sitei377Involved in electron transfer from the protein surface to the FAD cofactor1 Publication1
Sitei400Involved in electron transfer from the protein surface to the FAD cofactor1 Publication1 Publication1
Binding sitei409ATPCombined sources1 Publication1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi247 – 251FADCombined sources1 Publication5
Nucleotide bindingi359 – 360ATPCombined sources1 Publication2
Nucleotide bindingi390 – 392FADCombined sources1 Publication3

GO - Molecular functioni

  • ATP binding Source: UniProtKB
  • blue light photoreceptor activity Source: TAIR
  • FAD binding Source: UniProtKB
  • identical protein binding Source: IntAct
  • kinase activity Source: UniProtKB
  • metal ion binding Source: UniProtKB-KW
  • protein kinase activity Source: TAIR

GO - Biological processi

Keywordsi

Molecular functionPhotoreceptor protein, Receptor
Biological processApoptosis, Plant defense, Sensory transduction
LigandATP-binding, Chromophore, FAD, Flavoprotein, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cryptochrome-11 Publication
Short name:
AtCry1 Publication
Short name:
Atcry11 Publication
Alternative name(s):
Blue light photoreceptor1 Publication
Protein BLUE LIGHT UNINHIBITED 11 Publication
Protein ELONGATED HYPOCOTYL 41 Publication
Protein OUT OF PHASE 2
Short name:
OOP2
Gene namesi
Name:CRY11 Publication
Synonyms:BLU11 Publication, HY41 Publication
Ordered Locus Names:At4g08920Imported
ORF Names:T3H13.14Imported, T3H13.5Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G08920
TAIRilocus:2138728 AT4G08920

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Disruption phenotypei

Prevents the shortening of period at 27 degrees Celsius, resulting in a long period phenotype. The double mutant cry1 cry2 is impaired in blue light signaling, resulting in long-period, lower-amplitude oscillations at 12 and 17 degrees Celsius and completely abolishing rhythms at 27 degrees Celsius (PubMed:23511208). Plants show reduced root and hypocotyl elongation in an anion channels activation-dependent manner at the plasma membrane, as well a reduced anthocyanin accumulation in blue light (PubMed:8528277, PubMed:12324610, PubMed:16703358, PubMed:21511871, PubMed:21511872, PubMed:9765547). Impaired blue/UV-A wavelengths-mediated inhibition of shoot regeneration (PubMed:22681544). Impaired detection of blue/green ratio in light leading to abnormal inhibition of hypocotyl growth (PubMed:20668058). Reduced attenuating effect of high fluence rates of blue light. This phenotype is stronger in the cry1 cry2 double mutant. Slow rate of curvature at low fluence rates of blue light in cry1 cry2 (PubMed:12857830). Lower anthocyanin accumulation in the phyB cry1 double mutant exposed to far-red light. Reduced chlorophyll levels in the phyB cry1 double mutant exposed to red light. In blue light, impaired cotyledon unfolding and smaller cotyledons, longer hypocotyls and less chlorophyll (PubMed:9733523). Impaired accumulation of reactive oxygen species (ROS) in double mutant cry1 cry2 exposed to high-intensity blue light (PubMed:25728686). Altered blue-light-triggered and singlet oxygen-mediated programmed cell death (PCD) (PubMed:17075038). The double mutant cry1 cry2 exhibits a reduced impact of near-null magnetic field on flowering in lower blue light intensity and short days (PubMed:26095447). Reduced hyponastic growth (differential growth-driven upward leaf movement) in low blue light fluence (PubMed:19558423). The double mutant cry1 cry2 is hyposensitive to the strigolactone analog GR24 (PubMed:24126495). The mutant cry1 exposed to a background of red light show severely impaired stomatal opening responses to blue light. The double mutant cry1 cry2 has reduced stomatal conductance, transpiration, and photosynthesis, particularly under the high irradiance of full sunlight at midday, associated with elevated abscisic acid levels (PubMed:22147516). The cry1 mutants grown in complete darkness have premature opening of the hypocotyl hook (PubMed:22855128). Reduced expression of nuclear genes encoding photoprotective components in response to extreme high light (PubMed:22786870). Reduced shade avoidance syndrome (SAS) when exposed to blue light attenuation (PubMed:21457375). Reduced growth at warm ambient temperatures (PubMed:21265897). Down-regulated local resistance and systemic acquired resistance (SAR) to Pseudomonas syringae pv. tomato (Pst.) DC3000 under continuous light conditions, leading to pathogen proliferation (PubMed:20053798). When grown in blue light, increased growth of lateral roots and reduced sensitivity to auxin (IAA) on this phenotype (PubMed:20133010).23 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi21D → N in cry1-401; genomes uncoupled mutant (gun) with defects in plastid-to-nucleus signaling. 1 Publication1
Mutagenesisi66S → N: Loss of dimerization and activity. Abnormal hypocotyl elongation in blue light. 2 Publications1
Mutagenesisi220G → D in hy4-6; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 2 Publications1
Mutagenesisi283G → E in hy4-5; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 2 Publications1
Mutagenesisi286S → N in cry1-402; genomes uncoupled mutant (gun) with defects in plastid-to-nucleus signaling. 1 Publication1
Mutagenesisi324W → F: Impaired photoreduction in vitro, but not in vivo or in whole cell extracts, due to an alternative electron transport that involves small metabolites. Abolished intra-protein electron transfer cascade and impaired conformational change upon photoexcitation. 2 Publications1
Mutagenesisi337G → D: Abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi340G → E in cry1-404 and hy4-1; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. Loss of activity. Genomes uncoupled mutant (gun) with defects in plastid-to-nucleus signaling. 4 Publications1
Mutagenesisi347G → E in hy4-16; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 2 Publications1
Mutagenesisi347G → R in hy4-15; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. Loss of dimerization and activity. 3 Publications1
Mutagenesisi380G → R: Constitutive light response. 1 Publication1
Mutagenesisi396D → N: Upon illumination, formation of the reduced anionic flavin (RED) flavin, useful for DNA repair, rather than the semi-reduced radical form (SR) flavin, which is correlated with cryptochrome activity. 1 Publication1
Mutagenesisi400W → F: Impaired photoreduction in vitro, but not in vivo or whole cell extracts, due to an alternative electron transport that involves small metabolites. 1 Publication1
Mutagenesisi407L → F: Gain of function mutant. Hypersensitive toward blue, red, and far-red light in hypocotyl growth inhibition. Very early flowering in short-day conditions, associated with enhanced expression of CO and FT. Impaired interaction with PHYB. 2 Publications1
Mutagenesisi462A → V: Loss of dimerization and activity. Abnormal hypocotyl elongation in blue light. 2 Publications1
Mutagenesisi515E → K in hy4-19; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi531E → K in hy4-20; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi549P → L in hy4-9; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi559E → K in hy4-22; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi576R → K in hy4-10; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi581R → K in hy4-23; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi611R → K in hy4-24; reduced anthocyanin accumulation and abnormal hypocotyl elongation in blue light. 1 Publication1
Mutagenesisi623E → K in cry1-403; genomes uncoupled mutant (gun) with defects in plastid-to-nucleus signaling. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000851211 – 681Cryptochrome-1Add BLAST681

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi80 ↔ 190Combined sources1 Publication
Modified residuei616PhosphoserineBy similarity1
Modified residuei621PhosphothreonineBy similarity1

Post-translational modificationi

Autophosphorylated; in response to blue light and when in complex with FAD cofactor (PubMed:12846824, PubMed:14523249, PubMed:9651577, PubMed:17073458). Kinase activity is optimal in the presence of magnesium ions, about 30 percent of the optimal activity in the presence of manganese ions, but inactive with calcium ions (PubMed:17073458). Adopts an open conformation when phosphorylated upon photoexcitation and thus interacts with signaling partner proteins (PubMed:21841916).1 Publication4 Publications

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

PaxDbiQ43125
PRIDEiQ43125

PTM databases

iPTMnetiQ43125

Expressioni

Tissue specificityi

Widely expressed (PubMed:8953250). Expressed in the aerial tissues (e.g. cotyledons and leaf primordia), but not detected in the roots (PubMed:11743105).2 Publications

Inductioni

Expression levels display circadian oscillations under constant conditions, with a high amplitude and an early phase, with maximal expression around 4-6 hours of the light phase. Induced by light (PubMed:11743105). Transcripts levels oscillate weakly and proportionally to temperature, but protein levels are stable, with higher levels at low temperature (12 degrees Celsius) (PubMed:23511208). Accumulates in response to low blue light (LBL) (PubMed:26724867).3 Publications

Gene expression databases

ExpressionAtlasiQ43125 baseline and differential
GenevisibleiQ43125 AT

Interactioni

Subunit structurei

Homodimer. Interacts with ADO1, COP1 and PHYA. Interacts specifically with the dark/far-red (Pr) state of PHYB, but not with the red light-activated (Pfr) (PubMed:22577138). Interacts with PIF4 and PIF5 in the nucleus in response to low blue light (LBL) (PubMed:26724867). Binds to SPA1 and SPA4 in response to blue light, this interaction prevents SPA1/COP1 complex formation and thus avoid COP1-dependent degradation of the transcription factor HY5 by the proteasome and promotes hypocotyl elongation (PubMed:21511872, PubMed:21511871). Interacts with TCP2 (PubMed:26596765). Binding to ATP mediates conformational changes which facilitate flavin binding (PubMed:19327354, PubMed:17073458).13 Publications

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi11769, 7 interactors
IntActiQ43125, 3 interactors
MINTiQ43125
STRINGi3702.AT4G08920.1

Structurei

Secondary structure

1681
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

DisProtiDP00474
ProteinModelPortaliQ43125
SMRiQ43125
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ43125

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 141Photolyase/cryptochrome alpha/betaSequence analysisAdd BLAST130

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 489CNT1, binds chromophores to sense blue light and mediate CRY dimerization1 PublicationAdd BLAST489
Regioni490 – 681CCT1/CCE1, mediates blue light signaling1 Publication1 PublicationAdd BLAST192

Domaini

The N-terminal domain CNT1 (1-489) is sufficient for autophosphorylation and is required for dimerization. The C-terminal domain CCT1 (490-681) of the homodimer binds to COP1.

Sequence similaritiesi

Belongs to the DNA photolyase class-1 family.Curated

Phylogenomic databases

eggNOGiKOG0133 Eukaryota
COG0415 LUCA
HOGENOMiHOG000245621
InParanoidiQ43125
KOiK12118
OMAiAINAYMW
OrthoDBiEOG0936047F

Family and domain databases

Gene3Di3.40.50.620, 2 hits
InterProiView protein in InterPro
IPR036134 Crypto/Photolyase_FAD-like_sf
IPR036155 Crypto/Photolyase_N_sf
IPR005101 Cryptochr/Photolyase_FAD-bd
IPR002081 Cryptochrome/DNA_photolyase_1
IPR020978 Cryptochrome_C
IPR014134 Cryptochrome_pln
IPR018394 DNA_photolyase_1_CS_C
IPR006050 DNA_photolyase_N
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF12546 Cryptochrome_C, 1 hit
PF00875 DNA_photolyase, 1 hit
PF03441 FAD_binding_7, 1 hit
PRINTSiPR00147 DNAPHOTLYASE
SUPFAMiSSF48173 SSF48173, 1 hit
SSF52425 SSF52425, 1 hit
TIGRFAMsiTIGR02766 crypt_chrom_pln, 1 hit
PROSITEiView protein in PROSITE
PS00394 DNA_PHOTOLYASES_1_1, 1 hit
PS00691 DNA_PHOTOLYASES_1_2, 1 hit
PS51645 PHR_CRY_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Q43125-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGSVSGCGS GGCSIVWFRR DLRVEDNPAL AAAVRAGPVI ALFVWAPEEE
60 70 80 90 100
GHYHPGRVSR WWLKNSLAQL DSSLRSLGTC LITKRSTDSV ASLLDVVKST
110 120 130 140 150
GASQIFFNHL YDPLSLVRDH RAKDVLTAQG IAVRSFNADL LYEPWEVTDE
160 170 180 190 200
LGRPFSMFAA FWERCLSMPY DPESPLLPPK KIISGDVSKC VADPLVFEDD
210 220 230 240 250
SEKGSNALLA RAWSPGWSNG DKALTTFING PLLEYSKNRR KADSATTSFL
260 270 280 290 300
SPHLHFGEVS VRKVFHLVRI KQVAWANEGN EAGEESVNLF LKSIGLREYS
310 320 330 340 350
RYISFNHPYS HERPLLGHLK FFPWAVDENY FKAWRQGRTG YPLVDAGMRE
360 370 380 390 400
LWATGWLHDR IRVVVSSFFV KVLQLPWRWG MKYFWDTLLD ADLESDALGW
410 420 430 440 450
QYITGTLPDS REFDRIDNPQ FEGYKFDPNG EYVRRWLPEL SRLPTDWIHH
460 470 480 490 500
PWNAPESVLQ AAGIELGSNY PLPIVGLDEA KARLHEALSQ MWQLEAASRA
510 520 530 540 550
AIENGSEEGL GDSAEVEEAP IEFPRDITME ETEPTRLNPN RRYEDQMVPS
560 570 580 590 600
ITSSLIRPEE DEESSLNLRN SVGDSRAEVP RNMVNTNQAQ QRRAEPASNQ
610 620 630 640 650
VTAMIPEFNI RIVAESTEDS TAESSSSGRR ERSGGIVPEW SPGYSEQFPS
660 670 680
EENGIGGGST TSSYLQNHHE ILNWRRLSQT G
Length:681
Mass (Da):76,695
Last modified:May 3, 2011 - v2
Checksum:i372A7E6DDC2AC076
GO

Sequence cautioni

The sequence AAB28725 differs from that shown. Reason: Frameshift at position 546.Curated
The sequence AAD17364 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB78016 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti40I → N in AAK32756 (PubMed:14593172).Curated1
Sequence conflicti654G → R in AAB28724 (PubMed:8232555).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S66907 mRNA Translation: AAB28724.1
S66909 mRNA Translation: AAB28725.2 Frameshift.
AF128396 Genomic DNA Translation: AAD17364.1 Sequence problems.
AL161513 Genomic DNA Translation: CAB78016.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE82696.1
AF361588 mRNA Translation: AAK32756.1
AY124863 mRNA Translation: AAM70572.1
PIRiH85089
S39058
RefSeqiNP_567341.1, NM_116961.5
UniGeneiAt.27730

Genome annotation databases

EnsemblPlantsiAT4G08920.1; AT4G08920.1; AT4G08920
GeneIDi826470
GrameneiAT4G08920.1; AT4G08920.1; AT4G08920
KEGGiath:AT4G08920

Similar proteinsi

Entry informationi

Entry nameiCRY1_ARATH
AccessioniPrimary (citable) accession number: Q43125
Secondary accession number(s): Q43126
, Q8L7Y1, Q9ASZ2, Q9M0S9, Q9ZPF0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 3, 2011
Last modified: September 12, 2018
This is version 168 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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