Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 165 (29 Sep 2021)
Sequence version 2 (01 Dec 2000)
Previous versions | rss
Add a publicationFeedback
Protein

Hexokinase-1

Gene

HXK1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Fructose and glucose phosphorylating enzyme (PubMed:7610198).

May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (PubMed:16920781).

Acts as sugar sensor which may regulate sugar-dependent gene repression or activation (PubMed:9014361, PubMed:12690200, PubMed:26528314).

Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism (PubMed:9014361, PubMed:12690200).

May regulate the execution of program cell death in plant cells (PubMed:16920781).

Promotes roots and leaves growth (PubMed:26528314).

5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

Measured in yeast lacking glucose and hexose kinase activity.1 Publication
  1. KM=44 µM for glucose1 Publication
  2. KM=17 mM for fructose1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.1 Publication
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

Pathwayi: glycolysis

This protein is involved in step 1 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.1 Publication This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei230Glucose-6-phosphateBy similarity1
Binding sitei253ATPBy similarity1
Binding sitei253Glucose-6-phosphateBy similarity1
Binding sitei284SubstrateCombined sources1 Publication1
Binding sitei315SubstrateCombined sources1 Publication1
Binding sitei478Glucose-6-phosphateBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi101 – 106ATPBy similarity6
Nucleotide bindingi320 – 321ATPBy similarity2
Nucleotide bindingi357 – 361ATPBy similarity5
Nucleotide bindingi441 – 445ATPBy similarity5

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT4G29130-MONOMER
MetaCyc:AT4G29130-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.1.1, 399

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00109;UER00180
UPA00242

Protein family/group databases

MoonProt database of moonlighting proteins

More...
MoonProti
Q42525

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hexokinase-11 Publication (EC:2.7.1.1PROSITE-ProRule annotation1 Publication)
Alternative name(s):
Protein GLUCOSE INSENSITIVE 21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HXK11 Publication
Synonyms:GIN21 Publication
Ordered Locus Names:At4g29130Imported
ORF Names:F19B15.160Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G29130

The Arabidopsis Information Resource

More...
TAIRi
locus:2119931, AT4G29130

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei4 – 24HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Plants display a glucose-insensitive phenotype which allows them to grow on high glucose concentration medium (>6% glucose) (PubMed:12690200, PubMed:26528314). Dwarf plants with reduced roots and leaves growth (PubMed:26528314).2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi104G → A: Abolishes glucose phosphorylation activity. 1 Publication1
Mutagenesisi177S → D: Abolishes glucose phosphorylation activity. 1 Publication1
Mutagenesisi416G → A in gin2-2; insensitive to glucose. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001976121 – 496Hexokinase-1Add BLAST496

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q42525

PRoteomics IDEntifications database

More...
PRIDEi
Q42525

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
228861

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q42525

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q42525

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in flowers and siliques, at intermediate levels in roots and stems, and at lower levels in rosette and cauline leaves.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q42525, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q42525, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RPT5B in nucleus.

Interacts with RHIP1 (PubMed:26528314).

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
14321, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q42525, 3 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT4G29130.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1496
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q42525

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 487HexokinasePROSITE-ProRule annotationAdd BLAST453

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni25 – 26Substrate bindingBy similarity2
Regioni90 – 228Hexokinase small subdomainPROSITE-ProRule annotationAdd BLAST139
Regioni101 – 105Glucose-6-phosphate bindingBy similarity5
Regioni177 – 178Substrate bindingBy similarity2
Regioni194 – 195Substrate bindingCombined sources1 Publication2
Regioni229 – 476Hexokinase large subdomainPROSITE-ProRule annotationAdd BLAST248
Regioni229 – 230Substrate bindingCombined sources1 Publication2
Regioni255 – 256Substrate bindingCombined sources1 Publication2
Regioni439 – 441Glucose-6-phosphate bindingBy similarity3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the hexokinase family.PROSITE-ProRule annotationCurated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1369, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_014393_5_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q42525

Identification of Orthologs from Complete Genome Data

More...
OMAi
TEWGSFA

Database of Orthologous Groups

More...
OrthoDBi
1153545at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q42525

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043129, ATPase_NBD
IPR001312, Hexokinase
IPR019807, Hexokinase_BS
IPR022673, Hexokinase_C
IPR022672, Hexokinase_N

The PANTHER Classification System

More...
PANTHERi
PTHR19443, PTHR19443, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00349, Hexokinase_1, 1 hit
PF03727, Hexokinase_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53067, SSF53067, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00378, HEXOKINASE_1, 1 hit
PS51748, HEXOKINASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q42525-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKVAVGATV VCTAAVCAVA VLVVRRRMQS SGKWGRVLAI LKAFEEDCAT
60 70 80 90 100
PISKLRQVAD AMTVEMHAGL ASDGGSKLKM LISYVDNLPS GDEKGLFYAL
110 120 130 140 150
DLGGTNFRVM RVLLGGKQER VVKQEFEEVS IPPHLMTGGS DELFNFIAEA
160 170 180 190 200
LAKFVATECE DFHLPEGRQR ELGFTFSFPV KQTSLSSGSL IKWTKGFSIE
210 220 230 240 250
EAVGQDVVGA LNKALERVGL DMRIAALVND TVGTLAGGRY YNPDVVAAVI
260 270 280 290 300
LGTGTNAAYV ERATAIPKWH GLLPKSGEMV INMEWGNFRS SHLPLTEFDH
310 320 330 340 350
TLDFESLNPG EQILEKIISG MYLGEILRRV LLKMAEDAAF FGDTVPSKLR
360 370 380 390 400
IPFIIRTPHM SAMHNDTSPD LKIVGSKIKD ILEVPTTSLK MRKVVISLCN
410 420 430 440 450
IIATRGARLS AAGIYGILKK LGRDTTKDEE VQKSVIAMDG GLFEHYTQFS
460 470 480 490
ECMESSLKEL LGDEASGSVE VTHSNDGSGI GAALLAASHS LYLEDS
Length:496
Mass (Da):53,707
Last modified:December 1, 2000 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6DC81CE114E0B52B
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA60333 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U18754 mRNA Translation: AAA60333.1 Different initiation.
U28214 mRNA Translation: AAB49908.1
AL078470 Genomic DNA Translation: CAB43927.1
AL161574 Genomic DNA Translation: CAB79671.1
CP002687 Genomic DNA Translation: AEE85590.1
AY075658 mRNA Translation: AAL77665.1
AY124809 mRNA Translation: AAM70518.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S71205

NCBI Reference Sequences

More...
RefSeqi
NP_194642.1, NM_119057.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G29130.1; AT4G29130.1; AT4G29130

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
829034

Gramene; a comparative resource for plants

More...
Gramenei
AT4G29130.1; AT4G29130.1; AT4G29130

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G29130

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18754 mRNA Translation: AAA60333.1 Different initiation.
U28214 mRNA Translation: AAB49908.1
AL078470 Genomic DNA Translation: CAB43927.1
AL161574 Genomic DNA Translation: CAB79671.1
CP002687 Genomic DNA Translation: AEE85590.1
AY075658 mRNA Translation: AAL77665.1
AY124809 mRNA Translation: AAM70518.1
PIRiS71205
RefSeqiNP_194642.1, NM_119057.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4QS7X-ray2.00A30-496[»]
4QS8X-ray1.80A30-496[»]
4QS9X-ray2.10A30-496[»]
SMRiQ42525
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi14321, 12 interactors
IntActiQ42525, 3 interactors
STRINGi3702.AT4G29130.1

Protein family/group databases

MoonProtiQ42525

PTM databases

iPTMnetiQ42525
SwissPalmiQ42525

Proteomic databases

PaxDbiQ42525
PRIDEiQ42525
ProteomicsDBi228861

Genome annotation databases

EnsemblPlantsiAT4G29130.1; AT4G29130.1; AT4G29130
GeneIDi829034
GrameneiAT4G29130.1; AT4G29130.1; AT4G29130
KEGGiath:AT4G29130

Organism-specific databases

AraportiAT4G29130
TAIRilocus:2119931, AT4G29130

Phylogenomic databases

eggNOGiKOG1369, Eukaryota
HOGENOMiCLU_014393_5_1_1
InParanoidiQ42525
OMAiTEWGSFA
OrthoDBi1153545at2759
PhylomeDBiQ42525

Enzyme and pathway databases

UniPathwayiUPA00109;UER00180
UPA00242
BioCyciARA:AT4G29130-MONOMER
MetaCyc:AT4G29130-MONOMER
BRENDAi2.7.1.1, 399

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q42525

Gene expression databases

ExpressionAtlasiQ42525, baseline and differential
GenevisibleiQ42525, AT

Family and domain databases

InterProiView protein in InterPro
IPR043129, ATPase_NBD
IPR001312, Hexokinase
IPR019807, Hexokinase_BS
IPR022673, Hexokinase_C
IPR022672, Hexokinase_N
PANTHERiPTHR19443, PTHR19443, 1 hit
PfamiView protein in Pfam
PF00349, Hexokinase_1, 1 hit
PF03727, Hexokinase_2, 1 hit
SUPFAMiSSF53067, SSF53067, 2 hits
PROSITEiView protein in PROSITE
PS00378, HEXOKINASE_1, 1 hit
PS51748, HEXOKINASE_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHXK1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q42525
Secondary accession number(s): Q42535
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 1, 2000
Last modified: September 29, 2021
This is version 165 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again