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Entry version 161 (26 Feb 2020)
Sequence version 1 (01 Nov 1996)
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Protein

LRR receptor-like serine/threonine-protein kinase ERECTA

Gene

ERECTA

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor kinase that, together with ERL1 and ERL2, regulates aerial architecture, including inflorescence (e.g. shoot apical meristem-originating organ shape, elongation of the internode and pedicels, and adaxial-abaxial polarity), and stomatal patterning (e.g. density and clustering), probably by tuning cell division and expansion. Redundantly involved with ERL1 in procambial development regulation. Forms a functional ligand-receptor pair with EPF2 (AC Q8LC53) (PubMed:22241782). Modulates plant transpiration efficiency by controlling stomatal density, leaf photosynthetic capacity, epidermal cell expansion, mesophyll cell proliferation and cell-cell contact. A phloem-specific expression of ER is sufficient for proper inflorescence architecture (PubMed:22474391). Probable major trait regulating canalization (maintenance of phenotype despite varying environment) in many aspect of the plant physiology (e.g. plant morphology, light-dependent leaves number, branch number, flowering time, phytate and mineral concentrations) by transducing microenvironmental variation into phenotypic differentiation (ecological amplifier). May maintain development integrity in heat stress conditions. Regulates cell wall composition and structure. Confers resistance to the pathogenic bacteria Ralstonia solanacearum and to the necrotrophic fungi Plectosphaerella cucumerina and Pythium irregulare, and required for callose deposition upon infection. Resistance to P.cucumerina seems cell wall-mediated. Forms a constitutive complex with TMM involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146).22 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei676ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei773Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi654 – 662ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Kinase, Receptor, Serine/threonine-protein kinase, Transferase
Biological processCell wall biogenesis/degradation, Plant defense
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LRR receptor-like serine/threonine-protein kinase ERECTA1 Publication (EC:2.7.11.1)
Alternative name(s):
Protein QUANTITATIVE RESISTANCE TO PLECTOSPHAERELLA 1
Protein QUANTITATIVE RESISTANCE TO RALSTONIA SOLANACEARUM 1
Protein TRANSPIRATION EFFICIENCY 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ERECTA1 Publication
Synonyms:ER, QRP1, QRS1, TE1
Ordered Locus Names:At2g26330Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007605 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2, ARATH_2
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G26330

The Arabidopsis Information Resource

More...
TAIRi
locus:2005507 AT2G26330

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini25 – 580ExtracellularSequence analysisAdd BLAST556
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei581 – 601HelicalSequence analysisAdd BLAST21
Topological domaini602 – 976CytoplasmicSequence analysisAdd BLAST375

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

In er-104 and er-105, small curly leaves and compact inflorescence with short thick siliques, increased canalization of rosette leaf number during long days.2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi282M → I in er-103; compact inflorescence with short siliques, but normal leaves. 2 Publications1
Mutagenesisi489G → D in er-117; compact inflorescence with short siliques and pedicels, and susceptibility to P.cucumerina. 2 Publications1
Mutagenesisi831D → N in er-114; compact inflorescence with short siliques and pedicels, and susceptibility to P.cucumerina. 2 Publications1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000038900025 – 976LRR receptor-like serine/threonine-protein kinase ERECTAAdd BLAST952

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi65N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi74N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi221N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi234N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi305N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi329N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi409N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi457N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi510N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi528N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi543N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei645PhosphothreonineBy similarity1
Modified residuei721PhosphotyrosineBy similarity1
Modified residuei760PhosphotyrosineBy similarity1
Modified residuei815PhosphotyrosineBy similarity1
Modified residuei823PhosphothreonineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q42371

PRoteomics IDEntifications database

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PRIDEi
Q42371

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q42371

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mostly expressed in shoot apical meristems (SAM), organ primordia, flowers, siliques and young rosette leaves, and, to a lower extent, in stems and cauline leaves. Expressed in growing inflorescence stems and pedicels. Detected in epidermis, phloem and xylem.3 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Strongly expressed in organ primordia and immature organs but weakly in mature organs. Observed in SAM at low levels during the vegetative growth with an increase at the transition to the reproductive growth phase. At the reproductive stage, localized in the young developing flowers. Expressed in inflorescence meristem and is up-regulated during flower initiation and formation of flower organs. Also found in cells that differentiate into pedicels.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q42371 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q42371 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer and heterodimer with ERL1 and TMM.

Interacts with EPF1, EPF2, EPFL4, EPFL5 and EPFL6.

Interacts with SERK1, SERK2, SERK3/BAK1 and SERK4 in a EPF2-induced manner (PubMed:26320950).

Interacts with EPFL9/STOMAGEN (PubMed:26083750).

6 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
2525, 48 interactors

Protein interaction database and analysis system

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IntActi
Q42371, 57 interactors

STRING: functional protein association networks

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STRINGi
3702.AT2G26330.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q42371

Database of comparative protein structure models

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ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati69 – 92LRR 1Add BLAST24
Repeati93 – 115LRR 2Add BLAST23
Repeati117 – 140LRR 3Add BLAST24
Repeati141 – 163LRR 4Add BLAST23
Repeati165 – 187LRR 5Add BLAST23
Repeati189 – 212LRR 6Add BLAST24
Repeati213 – 235LRR 7Add BLAST23
Repeati237 – 259LRR 8Add BLAST23
Repeati260 – 282LRR 9Add BLAST23
Repeati284 – 306LRR 10Add BLAST23
Repeati308 – 330LRR 11Add BLAST23
Repeati332 – 355LRR 12Add BLAST24
Repeati356 – 379LRR 13Add BLAST24
Repeati380 – 401LRR 14Add BLAST22
Repeati404 – 425LRR 15Add BLAST22
Repeati428 – 449LRR 16Add BLAST22
Repeati452 – 473LRR 17Add BLAST22
Repeati476 – 498LRR 18Add BLAST23
Repeati500 – 522LRR 19Add BLAST23
Repeati523 – 545LRR 20Add BLAST23
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini648 – 918Protein kinasePROSITE-ProRule annotationAdd BLAST271

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The kinase domain is not required for ligand binding.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IFET Eukaryota
COG0515 LUCA
COG4886 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_000288_22_1_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q42371

KEGG Orthology (KO)

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KOi
K20718

Identification of Orthologs from Complete Genome Data

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OMAi
VYEDIMT

Database of Orthologous Groups

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OrthoDBi
826997at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q42371

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.80.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR013210 LRR_N_plant-typ
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13516 LRR_6, 2 hits
PF13855 LRR_8, 2 hits
PF08263 LRRNT_2, 1 hit
PF00069 Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00369 LRR_TYP, 8 hits
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS51450 LRR, 17 hits
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q42371-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALFRDIVLL GFLFCLSLVA TVTSEEGATL LEIKKSFKDV NNVLYDWTTS
60 70 80 90 100
PSSDYCVWRG VSCENVTFNV VALNLSDLNL DGEISPAIGD LKSLLSIDLR
110 120 130 140 150
GNRLSGQIPD EIGDCSSLQN LDLSFNELSG DIPFSISKLK QLEQLILKNN
160 170 180 190 200
QLIGPIPSTL SQIPNLKILD LAQNKLSGEI PRLIYWNEVL QYLGLRGNNL
210 220 230 240 250
VGNISPDLCQ LTGLWYFDVR NNSLTGSIPE TIGNCTAFQV LDLSYNQLTG
260 270 280 290 300
EIPFDIGFLQ VATLSLQGNQ LSGKIPSVIG LMQALAVLDL SGNLLSGSIP
310 320 330 340 350
PILGNLTFTE KLYLHSNKLT GSIPPELGNM SKLHYLELND NHLTGHIPPE
360 370 380 390 400
LGKLTDLFDL NVANNDLEGP IPDHLSSCTN LNSLNVHGNK FSGTIPRAFQ
410 420 430 440 450
KLESMTYLNL SSNNIKGPIP VELSRIGNLD TLDLSNNKIN GIIPSSLGDL
460 470 480 490 500
EHLLKMNLSR NHITGVVPGD FGNLRSIMEI DLSNNDISGP IPEELNQLQN
510 520 530 540 550
IILLRLENNN LTGNVGSLAN CLSLTVLNVS HNNLVGDIPK NNNFSRFSPD
560 570 580 590 600
SFIGNPGLCG SWLNSPCHDS RRTVRVSISR AAILGIAIGG LVILLMVLIA
610 620 630 640 650
ACRPHNPPPF LDGSLDKPVT YSTPKLVILH MNMALHVYED IMRMTENLSE
660 670 680 690 700
KYIIGHGASS TVYKCVLKNC KPVAIKRLYS HNPQSMKQFE TELEMLSSIK
710 720 730 740 750
HRNLVSLQAY SLSHLGSLLF YDYLENGSLW DLLHGPTKKK TLDWDTRLKI
760 770 780 790 800
AYGAAQGLAY LHHDCSPRII HRDVKSSNIL LDKDLEARLT DFGIAKSLCV
810 820 830 840 850
SKSHTSTYVM GTIGYIDPEY ARTSRLTEKS DVYSYGIVLL ELLTRRKAVD
860 870 880 890 900
DESNLHHLIM SKTGNNEVME MADPDITSTC KDLGVVKKVF QLALLCTKRQ
910 920 930 940 950
PNDRPTMHQV TRVLGSFMLS EQPPAATDTS ATLAGSCYVD EYANLKTPHS
960 970
VNCSSMSASD AQLFLRFGQV ISQNSE
Length:976
Mass (Da):107,334
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0E51D46A4AB94C8D
GO

<p>This subsection of the 'Sequence' section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement%5Fin%5Fdisease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

The cultivar Landsberg erecta (cv. Ler) derives from cv. Landsberg (cv. La-0) in which ERECTA is mutated at Ile-750 (variant er).

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti750I → K Er-1 in strain: cv. Landsberg erecta; round leaves, compact inflorescence, blunt fruits, short and thick siliques and petioles, susceptibility to pathogens such as R.solanacearum, P.irregulare and P.cucumerina, abnormal cell-wall composition and increased canalization of rosette leaf number during long days. In er-101 and er-102, compact inflorescence with short siliques and pedicels. 6 Publications1
Natural varianti886V → M in strain: cv. Mt-0. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
D83257 Genomic DNA Translation: BAA11869.1
U47029 mRNA Translation: AAC49302.1
AC004484 Genomic DNA Translation: AAC14518.1
CP002685 Genomic DNA Translation: AEC07825.1
AY035110 mRNA Translation: AAK59615.1
FJ708701 mRNA Translation: ACN59296.1
AK221886 mRNA Translation: BAD94220.1
EF598332 Genomic DNA Translation: ABR08864.1
EF598333 Genomic DNA Translation: ABR08865.1
EF598334 Genomic DNA Translation: ABR08866.1
EF598335 Genomic DNA Translation: ABR08867.1
EF598336 Genomic DNA Translation: ABR08868.1
EF598337 Genomic DNA Translation: ABR08869.1
EF598338 Genomic DNA Translation: ABR08870.1
EF598339 Genomic DNA Translation: ABR08871.1
EF598340 Genomic DNA Translation: ABR08872.1
EF598341 Genomic DNA Translation: ABR08873.1
EF598342 Genomic DNA Translation: ABR08874.1
EF598343 Genomic DNA Translation: ABR08875.1
EF598344 Genomic DNA Translation: ABR08876.1
EF598345 Genomic DNA Translation: ABR08877.1
EF598346 Genomic DNA Translation: ABR08878.1
EF598347 Genomic DNA Translation: ABR08879.1
EF598348 Genomic DNA Translation: ABR08880.1
EF598349 Genomic DNA Translation: ABR08881.1
EF598350 Genomic DNA Translation: ABR08882.1
EF598351 Genomic DNA Translation: ABR08883.1
EF598352 Genomic DNA Translation: ABR08884.1
EF598353 Genomic DNA Translation: ABR08885.1
EF598354 Genomic DNA Translation: ABR08886.1

Protein sequence database of the Protein Information Resource

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PIRi
B84659

NCBI Reference Sequences

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RefSeqi
NP_180201.1, NM_128190.3

Genome annotation databases

Ensembl plant genome annotation project

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EnsemblPlantsi
AT2G26330.1; AT2G26330.1; AT2G26330

Database of genes from NCBI RefSeq genomes

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GeneIDi
817173

Gramene; a comparative resource for plants

More...
Gramenei
AT2G26330.1; AT2G26330.1; AT2G26330

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT2G26330

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

PlantP kinase Classification PPC
Protein Spotlight

A complicated affair - Issue 116 of April 2010

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83257 Genomic DNA Translation: BAA11869.1
U47029 mRNA Translation: AAC49302.1
AC004484 Genomic DNA Translation: AAC14518.1
CP002685 Genomic DNA Translation: AEC07825.1
AY035110 mRNA Translation: AAK59615.1
FJ708701 mRNA Translation: ACN59296.1
AK221886 mRNA Translation: BAD94220.1
EF598332 Genomic DNA Translation: ABR08864.1
EF598333 Genomic DNA Translation: ABR08865.1
EF598334 Genomic DNA Translation: ABR08866.1
EF598335 Genomic DNA Translation: ABR08867.1
EF598336 Genomic DNA Translation: ABR08868.1
EF598337 Genomic DNA Translation: ABR08869.1
EF598338 Genomic DNA Translation: ABR08870.1
EF598339 Genomic DNA Translation: ABR08871.1
EF598340 Genomic DNA Translation: ABR08872.1
EF598341 Genomic DNA Translation: ABR08873.1
EF598342 Genomic DNA Translation: ABR08874.1
EF598343 Genomic DNA Translation: ABR08875.1
EF598344 Genomic DNA Translation: ABR08876.1
EF598345 Genomic DNA Translation: ABR08877.1
EF598346 Genomic DNA Translation: ABR08878.1
EF598347 Genomic DNA Translation: ABR08879.1
EF598348 Genomic DNA Translation: ABR08880.1
EF598349 Genomic DNA Translation: ABR08881.1
EF598350 Genomic DNA Translation: ABR08882.1
EF598351 Genomic DNA Translation: ABR08883.1
EF598352 Genomic DNA Translation: ABR08884.1
EF598353 Genomic DNA Translation: ABR08885.1
EF598354 Genomic DNA Translation: ABR08886.1
PIRiB84659
RefSeqiNP_180201.1, NM_128190.3

3D structure databases

SMRiQ42371
ModBaseiSearch...

Protein-protein interaction databases

BioGridi2525, 48 interactors
IntActiQ42371, 57 interactors
STRINGi3702.AT2G26330.1

PTM databases

iPTMnetiQ42371

Proteomic databases

PaxDbiQ42371
PRIDEiQ42371

Genome annotation databases

EnsemblPlantsiAT2G26330.1; AT2G26330.1; AT2G26330
GeneIDi817173
GrameneiAT2G26330.1; AT2G26330.1; AT2G26330
KEGGiath:AT2G26330

Organism-specific databases

AraportiAT2G26330
TAIRilocus:2005507 AT2G26330

Phylogenomic databases

eggNOGiENOG410IFET Eukaryota
COG0515 LUCA
COG4886 LUCA
HOGENOMiCLU_000288_22_1_1
InParanoidiQ42371
KOiK20718
OMAiVYEDIMT
OrthoDBi826997at2759
PhylomeDBiQ42371

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q42371

Gene expression databases

ExpressionAtlasiQ42371 baseline and differential
GenevisibleiQ42371 AT

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR013210 LRR_N_plant-typ
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF13516 LRR_6, 2 hits
PF13855 LRR_8, 2 hits
PF08263 LRRNT_2, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 8 hits
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 17 hits
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiERECT_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q42371
Secondary accession number(s): A5YYA0, A5YYB1, Q56WZ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: November 1, 1996
Last modified: February 26, 2020
This is version 161 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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