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Entry version 71 (08 May 2019)
Sequence version 1 (27 Sep 2005)
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Protein

Sodium-coupled monocarboxylate transporter 1

Gene

slc5a8

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as an electrogenic sodium (Na+) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na+:substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane.1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=169 µM for L-lactate1 Publication
  2. KM=535 µM for nicotinate1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processIon transport, Sodium transport, Symport, Transport
    LigandSodium

    Protein family/group databases

    Transport Classification Database

    More...
    TCDBi
    2.A.21.5.5 the solute:sodium symporter (sss) family

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Sodium-coupled monocarboxylate transporter 1
    Alternative name(s):
    Electrogenic sodium monocarboxylate cotransporter
    Short name:
    zSMCTe
    Sodium solute symporter family 5 member 8 protein
    Solute carrier family 5 member 8
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:slc5a8By similarity
    Synonyms:slc5a8lImported, smcteImported
    ORF Names:zgc:152716
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

    Organism-specific databases

    Zebrafish Information Network genome database

    More...
    ZFINi
    ZDB-GENE-061110-98 slc5a8l

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 10ExtracellularSequence analysis10
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
    Topological domaini32 – 52CytoplasmicSequence analysisAdd BLAST21
    Transmembranei53 – 73HelicalSequence analysisAdd BLAST21
    Topological domaini74 – 87ExtracellularSequence analysisAdd BLAST14
    Transmembranei88 – 108HelicalSequence analysisAdd BLAST21
    Topological domaini109 – 134CytoplasmicSequence analysisAdd BLAST26
    Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
    Topological domaini156 – 162ExtracellularSequence analysis7
    Transmembranei163 – 183HelicalSequence analysisAdd BLAST21
    Topological domaini184 – 193CytoplasmicSequence analysis10
    Transmembranei194 – 216HelicalSequence analysisAdd BLAST23
    Topological domaini217 – 240ExtracellularSequence analysisAdd BLAST24
    Transmembranei241 – 261HelicalSequence analysisAdd BLAST21
    Topological domaini262 – 284CytoplasmicSequence analysisAdd BLAST23
    Transmembranei285 – 305HelicalSequence analysisAdd BLAST21
    Topological domaini306 – 340ExtracellularSequence analysisAdd BLAST35
    Transmembranei341 – 363HelicalSequence analysisAdd BLAST23
    Topological domaini364 – 390CytoplasmicSequence analysisAdd BLAST27
    Transmembranei391 – 411HelicalSequence analysisAdd BLAST21
    Topological domaini412 – 414ExtracellularSequence analysis3
    Transmembranei415 – 435HelicalSequence analysisAdd BLAST21
    Topological domaini436 – 440CytoplasmicSequence analysis5
    Transmembranei441 – 461HelicalSequence analysisAdd BLAST21
    Topological domaini462 – 519ExtracellularSequence analysisAdd BLAST58
    Transmembranei520 – 540HelicalSequence analysisAdd BLAST21
    Topological domaini541 – 610CytoplasmicSequence analysisAdd BLAST70

    Keywords - Cellular componenti

    Membrane

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003345011 – 610Sodium-coupled monocarboxylate transporter 1Add BLAST610

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi220N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi485N-linked (GlcNAc...) asparagineSequence analysis1

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q3ZMH1

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed in brain and eye 24 hours post-fertilization. In the 5 day old embryo, detected in swim bladder, pronephros (embryonic kidney), pronephric tube, and pronephric ducts, brain, trabecular bar, eyes, otic capsule, stomach, gall bladder, and gut.1 Publication

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    7955.ENSDARP00000030637

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG2349 Eukaryota
    COG0591 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000261662

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q3ZMH1

    KEGG Orthology (KO)

    More...
    KOi
    K14388

    Database of Orthologous Groups

    More...
    OrthoDBi
    1180002at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q3ZMH1

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd11519 SLC5sbd_SMCT1, 1 hit

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    1.20.1730.10, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR038377 Na/Glc_symporter_sf
    IPR001734 Na/solute_symporter
    IPR041992 SLC5sbd_SMCT1

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00474 SSF, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR00813 sss, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS50283 NA_SOLUT_SYMP_3, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

    Q3ZMH1-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MPGSGGPVAT FSVWDYVVFA GLILVAAGIG LFQSFRGRKE ASSDEFLLGG
    60 70 80 90 100
    RQMTAVPVAL SLTASFMSGI TVIGTPAEAY LYGTPFWLFF ISYAIMSTIS
    110 120 130 140 150
    AEIFVPLFYR LNITSTYEYL EMRYNKLIRV IGTSMYIIQT ALYTGMVIFA
    160 170 180 190 200
    PALALNQITG LDLWGVLVAT GAVCIIYCTL GGLKAVIWTD VFQMIIMLGG
    210 220 230 240 250
    FVAVIARGAV LQGGLGRVWN DSFYGGRLET FSFDPDPLRR HSFWTIVVGG
    260 270 280 290 300
    SLMWASMYSI NQSQVQRYIS CRTMTHAKLS LYVNMVGLWV TVSLAMMSGL
    310 320 330 340 350
    TMYSIYKDCD PFTNKDVGAT DQLLPYLVMD ILADFPGLPG LFVAAAYSGT
    360 370 380 390 400
    LSTVSSSINA LVAVTVEDFM KPAWPSLTER QLSWINMGMS VFYGAVCIGM
    410 420 430 440 450
    AGVASMMGNI LQAALSIFGM ISGPLLGLYM LGMFFRCANS TGGLAGLASG
    460 470 480 490 500
    LAITLWVGIG AQLYPPLPEK TLRLPLSVEG CVALNTSETT TMTPFSTVLQ
    510 520 530 540 550
    TTTPQPRPAL ADNWYSLSYL YFSPVGIVVT MIIALIVSAI SGGCKQKKVR
    560 570 580 590 600
    PELFISKSDL ICFRCKKSDS EVSDLIETKP KDNQGLDSPV FYDNEIVLKE
    610
    KDQQEKITKL
    Length:610
    Mass (Da):66,359
    Last modified:September 27, 2005 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF6A6E706A1DB2321
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    F1RCK0F1RCK0_DANRE
    Solute carrier family 5 member 8,-l...
    slc5a8l
    610Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F1QN15F1QN15_DANRE
    Solute carrier family 5 member 8,-l...
    slc5a8l
    159Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A2R8QH45A0A2R8QH45_DANRE
    Solute carrier family 5 member 8,-l...
    slc5a8l
    610Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti453I → V in AAI24586 (Ref. 2) Curated1
    Sequence conflicti528V → I in AAI24586 (Ref. 2) Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AY727859 mRNA Translation: AAW55811.1
    BC124585 mRNA Translation: AAI24586.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001030141.1, NM_001034969.1

    Genome annotation databases

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    556156

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    dre:556156

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AY727859 mRNA Translation: AAW55811.1
    BC124585 mRNA Translation: AAI24586.1
    RefSeqiNP_001030141.1, NM_001034969.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000030637

    Protein family/group databases

    TCDBi2.A.21.5.5 the solute:sodium symporter (sss) family

    Proteomic databases

    PaxDbiQ3ZMH1

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    GeneIDi556156
    KEGGidre:556156

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    556156
    ZFINiZDB-GENE-061110-98 slc5a8l

    Phylogenomic databases

    eggNOGiKOG2349 Eukaryota
    COG0591 LUCA
    HOGENOMiHOG000261662
    InParanoidiQ3ZMH1
    KOiK14388
    OrthoDBi1180002at2759
    PhylomeDBiQ3ZMH1

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:Q3ZMH1

    Family and domain databases

    CDDicd11519 SLC5sbd_SMCT1, 1 hit
    Gene3Di1.20.1730.10, 1 hit
    InterProiView protein in InterPro
    IPR038377 Na/Glc_symporter_sf
    IPR001734 Na/solute_symporter
    IPR041992 SLC5sbd_SMCT1
    PfamiView protein in Pfam
    PF00474 SSF, 1 hit
    TIGRFAMsiTIGR00813 sss, 1 hit
    PROSITEiView protein in PROSITE
    PS50283 NA_SOLUT_SYMP_3, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSC5A8_DANRE
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3ZMH1
    Secondary accession number(s): A0AUP7
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: September 27, 2005
    Last modified: May 8, 2019
    This is version 71 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
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