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Protein

Asporin

Gene

ASPN

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Asporin
Gene namesi
Name:ASPN
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 8

Organism-specific databases

VGNCiVGNC:26222 ASPN

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrix, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_000028771616 – 370AsporinAdd BLAST355

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi45O-linked (GalNAc...) serineBy similarity1
Disulfide bondi65 ↔ 71By similarity
Disulfide bondi69 ↔ 78By similarity
Glycosylationi272N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi323 ↔ 356By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ3ZBN5
PeptideAtlasiQ3ZBN5
PRIDEiQ3ZBN5

Expressioni

Gene expression databases

BgeeiENSBTAG00000011847

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000034926

Structurei

3D structure databases

ProteinModelPortaliQ3ZBN5
SMRiQ3ZBN5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 92LRRNTAdd BLAST37
Repeati93 – 114LRR 1Add BLAST22
Repeati117 – 138LRR 2Add BLAST22
Repeati141 – 163LRR 3Add BLAST23
Repeati164 – 183LRR 4Add BLAST20
Repeati186 – 209LRR 5Add BLAST24
Repeati232 – 253LRR 6Add BLAST22
Repeati256 – 277LRR 7Add BLAST22
Repeati280 – 302LRR 8Add BLAST23
Repeati303 – 324LRR 9Add BLAST22
Repeati332 – 354LRR 10Add BLAST23
Repeati355 – 370LRR 11Add BLAST16

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi65 – 78Cys-richAdd BLAST14

Sequence similaritiesi

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal

Phylogenomic databases

eggNOGiKOG0619 Eukaryota
COG4886 LUCA
GeneTreeiENSGT00760000118969
HOGENOMiHOG000261690
HOVERGENiHBG016052
InParanoidiQ3ZBN5
KOiK08120
OMAiVTVFHIR
OrthoDBiEOG091G044B
TreeFamiTF334562

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR028548 Asporin
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR026906 LRR_5
IPR032675 LRR_dom_sf
IPR000372 LRRNT
IPR016352 SLRP_I_decor/aspor/byglycan
PANTHERiPTHR44053:SF3 PTHR44053:SF3, 1 hit
PfamiView protein in Pfam
PF13306 LRR_5, 1 hit
PF13855 LRR_8, 2 hits
PF01462 LRRNT, 1 hit
PIRSFiPIRSF002490 SLRP_I, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 8 hits
SM00013 LRRNT, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 7 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3ZBN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVYVLLVFL TLCSAKPLFH PSYLTLKNLM LKDMEDEGDS DADNSLFPTR
60 70 80 90 100
EPINPFFPFD LFSTCPFGCQ CYSRVVHCSD LGLSSVPSNI PFDTRMVDLQ
110 120 130 140 150
NNKIKEIKEN DFKGLTSLYA LILNNNKLTK IHPKAFLTTK KLRRLYLSHN
160 170 180 190 200
QLSEIPLNLP KSLAELRIHD NKVKKIQKAT FKGMNALHVL EMSANPLDNN
210 220 230 240 250
GIEPGAFEGV TVFHIRIAEA KLTSIPKELP STLLELHLDY NKISVVELED
260 270 280 290 300
FKRYKDLQRL GLGNNRITDI ENGSLANIPR VREIHLENNK LKKVPSGLQE
310 320 330 340 350
LKYLQIIFLH SNSITKVGVN DFCPTVPKMK KSLYSAISLS NNPVKYWEVQ
360 370
PATFRCVLSR MSVQLGNFRK
Length:370
Mass (Da):42,119
Last modified:September 27, 2005 - v1
Checksum:iDDBDA88F5F8DC190
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103199 mRNA Translation: AAI03200.1
RefSeqiNP_001029481.1, NM_001034309.2
UniGeneiBt.45145

Genome annotation databases

EnsembliENSBTAT00000035046; ENSBTAP00000034926; ENSBTAG00000011847
GeneIDi507990
KEGGibta:507990

Similar proteinsi

Entry informationi

Entry nameiASPN_BOVIN
AccessioniPrimary (citable) accession number: Q3ZBN5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: September 27, 2005
Last modified: June 20, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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