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Protein
Submitted name:

Cytochrome P450, family 19, subfamily a, polypeptide 1

Gene

Cyp19a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 19, subfamily a, polypeptide 1Imported
Gene namesi
Name:Cyp19a1Imported
ORF Names:mCG_7170Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88587 Cyp19a1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000032274 Expressed in 32 organ(s), highest expression level in tertiary ovarian follicle

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili241 – 261Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
HOVERGENiHBG050750
KOiK07434
OMAiMRRIMLD
OrthoDBiEOG091G056R

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q3ZAT3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFLEMLNPMQ YNVTIMVPET VTVSAMPLLL IMGLLLLIWN CESSSSIPGP
60 70 80 90 100
GYCLGIGPLI SHGRFLWMGI GSACNYYNKM YGEFMRVWIS GEETLIISKS
110 120 130 140 150
SSMFHVMKHS HYISRFGSKR GLQCIGMHEN GIIFNNNPSL WRTIRPFFMK
160 170 180 190 200
ALTGPGLVRM VEVCVESIKQ HLDRLGEVTD TSGYVDVLTL MRHIMLDTSN
210 220 230 240 250
MLFLGIPLDE SAIVKKIQGY FNAWQALLIK PNIFFKISWL YRKYERSVKD
260 270 280 290 300
LKDEIAVLVE KKRHKVSTAE KLEDCMDFAT DLIFAERRGD LTKENVNQCI
310 320 330 340 350
LEMLIAAPDT MSVTLYFMLL LVAEYPEVEA AILKEIHTVV GDRDIKIEDI
360 370 380 390 400
QNLKVVENFI NESMRYQPVV DLVMRRALED DVIDGYPVKK GTNIILNIGR
410 420 430 440 450
MHRLEYFPKP NEFTLENFEK NVPYRYFQPF GFGPRGCAGK YIAMVMMKVV
460 470 480 490 500
LVTLLRRFQV KTLQKRCIEN IPKKNDLSLH PNEDRHLVEI IFSPRNSDKY

LQQ
Length:503
Mass (Da):58,015
Last modified:September 27, 2005 - v1
Checksum:i737400389D1AEFF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103670 mRNA Translation: AAI03671.1
BC104489 mRNA Translation: AAI04490.1
AK143323 mRNA Translation: BAE25342.1
CH466522 Genomic DNA Translation: EDL25809.1
RefSeqiNP_001335100.1, NM_001348171.1
NP_001335101.1, NM_001348172.1
NP_001335102.1, NM_001348173.1
NP_031836.1, NM_007810.4
UniGeneiMm.478781
Mm.5199

Genome annotation databases

GeneIDi13075
KEGGimmu:13075

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103670 mRNA Translation: AAI03671.1
BC104489 mRNA Translation: AAI04490.1
AK143323 mRNA Translation: BAE25342.1
CH466522 Genomic DNA Translation: EDL25809.1
RefSeqiNP_001335100.1, NM_001348171.1
NP_001335101.1, NM_001348172.1
NP_001335102.1, NM_001348173.1
NP_031836.1, NM_007810.4
UniGeneiMm.478781
Mm.5199

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13075
KEGGimmu:13075

Organism-specific databases

CTDi1588
MGIiMGI:88587 Cyp19a1

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
HOVERGENiHBG050750
KOiK07434
OMAiMRRIMLD
OrthoDBiEOG091G056R

Miscellaneous databases

ChiTaRSiCyp19a1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000032274 Expressed in 32 organ(s), highest expression level in tertiary ovarian follicle

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ3ZAT3_MOUSE
AccessioniPrimary (citable) accession number: Q3ZAT3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: October 10, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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