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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) (Dehalococcoides ethenogenes (strain 195))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei13SubstrateUniRule annotation1
Binding sitei17SubstrateUniRule annotation1
Binding sitei92SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotation (EC:4.2.3.3UniRule annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotation
Ordered Locus Names:DET1576Imported
OrganismiDehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) (Dehalococcoides ethenogenes (strain 195))Imported
Taxonomic identifieri243164 [NCBI]
Taxonomic lineageiBacteriaChloroflexiDehalococcoidiaDehalococcoidalesDehalococcoidaceaeDehalococcoides
Proteomesi
  • UP000008289 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243164.DET1576

Structurei

3D structure databases

ProteinModelPortaliQ3Z676
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 112MGSInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni59 – 60Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1803 LUCA
HOGENOMiHOG000283729
OMAiFAWRELV
OrthoDBiPOG091H04UH

Family and domain databases

Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit

Sequencei

Sequence statusi: Complete.

Q3Z676-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEPKITLGL IAHNNCKKDM VHLIQAYAHL MKGHHLIATK STGELIRKHT
60 70 80 90 100
GLPVILKESG PDGGELQLGG FVASGIIKAV IFLRDPLKRK SHEPDVTALM
110 120 130 140
RVCDAHNIPL ATNRATAACV LHTVLFHPDK LEDMPPKESD DDP
Length:143
Mass (Da):15,662
Last modified:September 27, 2005 - v1
Checksum:i7727D78BDE918592
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000027 Genomic DNA Translation: AAW39175.1
RefSeqiWP_010937249.1, NC_002936.3

Genome annotation databases

EnsemblBacteriaiAAW39175; AAW39175; DET1576
GeneIDi3229133
KEGGidet:DET1576
PATRICifig|243164.10.peg.1488

Similar proteinsi

Entry informationi

Entry nameiQ3Z676_DEHM1
AccessioniPrimary (citable) accession number: Q3Z676
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: June 20, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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