UniProtKB - Q3V3X3 (Q3V3X3_MOUSE)
Protein
Transcription factor
Gene
Tfdp1
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- protein domain specific binding Source: Ensembl
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: Ensembl
- transcription factor binding Source: Ensembl
GO - Biological processi
- positive regulation of DNA-binding transcription factor activity Source: Ensembl
- positive regulation of G1/S transition of mitotic cell cycle Source: Ensembl
- transcription by RNA polymerase II Source: Ensembl
Keywordsi
Molecular function | DNA-bindingUniRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription factorUniRule annotation |
Gene namesi | Name:Tfdp1Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:101934, Tfdp1 |
Subcellular locationi
Nucleus
- Nucleus UniRule annotationARBA annotation
Cytosol
- cytosol Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
Other locations
- RNA polymerase II transcription regulator complex Source: Ensembl
Keywords - Cellular componenti
NucleusUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000038482, Expressed in pineal body and 341 other tissues |
ExpressionAtlasi | Q3V3X3, baseline and differential |
Interactioni
GO - Molecular functioni
- protein domain specific binding Source: Ensembl
- transcription factor binding Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 111 – 193 | E2F_TDPInterPro annotationAdd BLAST | 83 | |
Domaini | 200 – 344 | DPInterPro annotationAdd BLAST | 145 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 79 – 114 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 370 – 410 | DisorderedSequence analysisAdd BLAST | 41 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 202 – 222 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 79 – 102 | PolarSequence analysisAdd BLAST | 24 | |
Compositional biasi | 370 – 387 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 393 – 410 | AcidicSequence analysisAdd BLAST | 18 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
HOGENOMi | CLU_039874_3_1_1 |
OMAi | HGKGLRH |
OrthoDBi | 1046304at2759 |
Family and domain databases
CDDi | cd14458, DP_DD, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 1.20.140.80, 1 hit |
InterProi | View protein in InterPro IPR028313, DP-1 IPR037241, E2F-DP_heterodim IPR003316, E2F_WHTH_DNA-bd_dom IPR038168, TF_DP_C_sf IPR014889, Transc_factor_DP_C IPR015648, Transcrpt_fac_DP IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12548, PTHR12548, 1 hit PTHR12548:SF4, PTHR12548:SF4, 1 hit |
Pfami | View protein in Pfam PF08781, DP, 1 hit PF02319, E2F_TDP, 1 hit |
PIRSFi | PIRSF009404, Transcription_factor_DP, 1 hit |
SMARTi | View protein in SMART SM01138, DP, 1 hit SM01372, E2F_TDP, 1 hit |
SUPFAMi | SSF144074, SSF144074, 1 hit SSF46785, SSF46785, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3V3X3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKDASLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVN TLGKQLLPKT
60 70 80 90 100
FGQSNVNITQ QVVIGTPQRP AASNTIVVGS PHTPNTHFVS QNQTSDSSPW
110 120 130 140 150
SAGKRNRKGE KNGKGLRHFS MKVCEKVQRK GTTSYNEVAD ELVAEFSAAD
160 170 180 190 200
NHILPNESAY DQKNIRRRVY DALNVLMAMN IISKEKKEIK WIGLPTNSAQ
210 220 230 240 250
ECQNLEVERQ RRLERIKQKQ SQLQELILQQ IAFKNLVQRN RQAEQQARRP
260 270 280 290 300
PPPNSVIHLP FIIVNTSRKT VIDCSISNDK FEYLFNFDNT FEIHDDIEVL
310 320 330 340 350
KRMGMACGLE SGNCSAEDLK VARSLVPKAL EPYVTEMAQG SIGGVFVTTT
360 370 380 390 400
GSTSNGTRLS ASDLSNGADG MLATSSNGSQ YSGSRVETPV SYVGEDDDDD
410
DDFNENDEED
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC132567 mRNA Translation: AAI32568.1 BC132569 mRNA Translation: AAI32570.1 BC145344 mRNA Translation: AAI45345.1 AK030820 mRNA Translation: BAE20457.1 |
RefSeqi | NP_001278694.1, NM_001291765.1 NP_001278695.1, NM_001291766.1 NP_001278697.1, NM_001291768.1 NP_033387.1, NM_009361.3 XP_006508814.1, XM_006508751.3 |
Genome annotation databases
GeneIDi | 21781 |
KEGGi | mmu:21781 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC132567 mRNA Translation: AAI32568.1 BC132569 mRNA Translation: AAI32570.1 BC145344 mRNA Translation: AAI45345.1 AK030820 mRNA Translation: BAE20457.1 |
RefSeqi | NP_001278694.1, NM_001291765.1 NP_001278695.1, NM_001291766.1 NP_001278697.1, NM_001291768.1 NP_033387.1, NM_009361.3 XP_006508814.1, XM_006508751.3 |
3D structure databases
SMRi | Q3V3X3 |
ModBasei | Search... |
Proteomic databases
EPDi | Q3V3X3 |
MaxQBi | Q3V3X3 |
Protocols and materials databases
Antibodypediai | 11828, 352 antibodies |
Genome annotation databases
GeneIDi | 21781 |
KEGGi | mmu:21781 |
Organism-specific databases
CTDi | 7027 |
MGIi | MGI:101934, Tfdp1 |
Phylogenomic databases
HOGENOMi | CLU_039874_3_1_1 |
OMAi | HGKGLRH |
OrthoDBi | 1046304at2759 |
Miscellaneous databases
BioGRID-ORCSi | 21781, 7 hits in 17 CRISPR screens |
ChiTaRSi | Tfdp1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000038482, Expressed in pineal body and 341 other tissues |
ExpressionAtlasi | Q3V3X3, baseline and differential |
Family and domain databases
CDDi | cd14458, DP_DD, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 1.20.140.80, 1 hit |
InterProi | View protein in InterPro IPR028313, DP-1 IPR037241, E2F-DP_heterodim IPR003316, E2F_WHTH_DNA-bd_dom IPR038168, TF_DP_C_sf IPR014889, Transc_factor_DP_C IPR015648, Transcrpt_fac_DP IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12548, PTHR12548, 1 hit PTHR12548:SF4, PTHR12548:SF4, 1 hit |
Pfami | View protein in Pfam PF08781, DP, 1 hit PF02319, E2F_TDP, 1 hit |
PIRSFi | PIRSF009404, Transcription_factor_DP, 1 hit |
SMARTi | View protein in SMART SM01138, DP, 1 hit SM01372, E2F_TDP, 1 hit |
SUPFAMi | SSF144074, SSF144074, 1 hit SSF46785, SSF46785, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3V3X3_MOUSE | |
Accessioni | Q3V3X3Primary (citable) accession number: Q3V3X3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | December 2, 2020 | |
This is version 147 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |