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Entry version 105 (07 Oct 2020)
Sequence version 2 (18 Mar 2008)
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Protein

Capping protein, Arp2/3 and myosin-I linker protein 2

Gene

Carmil2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization. Plays a role in cell protrusion formations; involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations. Involved as well in cell migration and invadopodia formation during wound healing (By similarity). Required for CD28-mediated stimulation of NF-kappa-B signaling, involved in naive T cells activation, maturation into T memory cells, and differentiation into T helper cells (PubMed:27647348). Required for CD28-mediated differentiation of T regulatory cells (By similarity).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Capping protein, Arp2/3 and myosin-I linker protein 2By similarity
Alternative name(s):
Capping protein regulator and myosin 1 linker 2Imported
F-actin-uncapping protein RLTPRCurated
Leucine-rich repeat-containing protein 16C
RGD, leucine-rich repeat, tropomodulin and proline-rich-containing proteinBy similarityImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Carmil2Imported
Synonyms:Lrrc16c, RltprImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685431, Carmil2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003262391 – 1296Capping protein, Arp2/3 and myosin-I linker protein 2Add BLAST1296

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1008PhosphoserineCombined sources1
Modified residuei1134PhosphoserineCombined sources1
Modified residuei1145PhosphothreonineCombined sources1
Modified residuei1191Omega-N-methylarginineCombined sources1
Modified residuei1203PhosphoserineCombined sources1
Modified residuei1281PhosphoserineCombined sources1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q3V3V9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q3V3V9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3V3V9

PeptideAtlas

More...
PeptideAtlasi
Q3V3V9

PRoteomics IDEntifications database

More...
PRIDEi
Q3V3V9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3V3V9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3V3V9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000050357, Expressed in thymus and 86 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3V3V9, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms homodimers.

Interacts (via C-terminus) with heterodimeric capping protein (CP); the interaction inhibits CP activity and hence promotes actin polymerization at the barbed end of actin filaments.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
231561, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q3V3V9, 20 interactors

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3V3V9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3V3V9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati63 – 87LRR 1Add BLAST25
Repeati88 – 110LRR 2Add BLAST23
Repeati248 – 271LRR 3Add BLAST24
Repeati273 – 296LRR 4Add BLAST24
Repeati305 – 328LRR 5Add BLAST24
Repeati363 – 386LRR 6Add BLAST24
Repeati395 – 415LRR 7Add BLAST21
Repeati426 – 448LRR 8Add BLAST23
Repeati453 – 477LRR 9Add BLAST25
Repeati480 – 506LRR 10Add BLAST27
Repeati515 – 538LRR 11Add BLAST24
Repeati542 – 565LRR 12Add BLAST24
Repeati570 – 594LRR 13Add BLAST25
Repeati598 – 621LRR 14Add BLAST24
Repeati836 – 859LRR 15Add BLAST24

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni507 – 601Tropomodulin-likeAdd BLAST95
Regioni975 – 1002Necessary for localization at the cell membraneBy similarityAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1199 – 1296Pro-richAdd BLAST98

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal leucine-rich repeat (LRR) domain is necessary for localization to vimentin filaments. The C-terminus is necessary for localization to the cell membrane.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CARMIL family.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_375944_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3V3V9

Database of Orthologous Groups

More...
OrthoDBi
208951at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3V3V9

TreeFam database of animal gene trees

More...
TreeFami
TF316381

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029763, CARMIL2
IPR031943, CARMIL_C
IPR041245, CARMIL_PH
IPR001611, Leu-rich_rpt
IPR032675, LRR_dom_sf
IPR011993, PH-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24112:SF32, PTHR24112:SF32, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17888, Carm_PH, 1 hit
PF16000, CARMIL_C, 2 hits
PF13516, LRR_6, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q3V3V9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAQTPDDISC ELRGEITRFL WPKEAELLLK TWLPQEGAEQ SHILALLRWR
60 70 80 90 100
AYLLHTCLPL RVDCTFSYLE VQAMALQETP PRVTFELESL PELVLEFPCV
110 120 130 140 150
AALEQLAQHV AAAIKKVFPR STLGKLFRKP TPSSLLARLE RSHPLESTIP
160 170 180 190 200
SSPCGGFLET YEALCDYNGF PFREEIQWDV DTIYHRQGCR HFCLGDFSHF
210 220 230 240 250
GSRDLALSVA ALSYNLWFRR LSCEDMKLSL EVSEQILHMT SQSSYLEELV
260 270 280 290 300
LEACGLRGDF VRRLAQALAG HFNSGLRELS LSGNLLDDRG MRALGRALAT
310 320 330 340 350
NATFDSTLTH LDLSGNPGAL GPSQDSGGLY TFLSRPNVLA YLNLAGTDAT
360 370 380 390 400
LGTLFTALAG GCCSSLTHLE ASRNIFSRMK SQAAPAALQR FLGGTRMLRH
410 420 430 440 450
LGLAGCKLPP EALRALLEGL ALNTQIHDLH LDLSACELRS VGAQVIQDLV
460 470 480 490 500
CDAGALSSLD LSDNGFGSDM VTLVLAIGRS RSLKHVALGR NFNVRCKETL
510 520 530 540 550
DDVLHRIAQL MQDDDCPLQS LSVAESRLKQ GASILIRALG TNPKLTALDI
560 570 580 590 600
SGNAIGDAGA KMLAKALRVN TRLRSVIWDR NNTSALGLLD VAQALEQNHS
610 620 630 640 650
LKSMPLPLND VTQAHRSRPE LTTRAVHQIQ ACLWRNNQVD STSDLKPCLQ
660 670 680 690 700
PLGLISDHSE QEVNELCQSV QEHMELLGCG AGPQGEVAVH QAEDAIQNAN
710 720 730 740 750
FSLSILPILY EAGRSPSHHW QLQQKLESLL GQVGEICRQD IQDFTQTTLD
760 770 780 790 800
TTRSLCPQML QTPGWRKQLE GVLVGSGGLP ELLPEHLLQD AFSRLRDMRL
810 820 830 840 850
SITGTLAESI VAQALAGLHA ARDRLVERLT QQAPVTMAPA VPPLGGNELS
860 870 880 890 900
PLETGGLEEL FFPTEKEEER EKVLLRKRNG TPSWQLRGKM QSRRLGRLHA
910 920 930 940 950
VAEKHWAAGP RDTPASAVYQ RVDVCVGWVP PALLQEGNGL TARVDEGVEE
960 970 980 990 1000
FFSKRLIQQD HFWAPEEDPA TEGGATPVPR TLRKKLGTLF AFKKPRSTRG
1010 1020 1030 1040 1050
PRPDLETSPG AAARARKSTL GDLLRPPARP GRGEEPGGAE GGTSSPDPAR
1060 1070 1080 1090 1100
RNRPRYTRES KAYSMILLPA EEEAAVGTRP DKRRPLERGD TELAPSFEQR
1110 1120 1130 1140 1150
VQVMLQRIGV SRASGGAESK RKQSKDGEIK KAGSDGDIMD SSTETPPISI
1160 1170 1180 1190 1200
KSRTHSVSAD PSCRPGPGGQ GPESATWKTL GQQLNAELRG RGWGQQDGPG
1210 1220 1230 1240 1250
PPSPCPSPSP RRTSPAPDIL SLPEDPCLGP RNEERPLRLQ RSPVLKRRPK
1260 1270 1280 1290
LEAPPSPSLG SGLGSKPLPP YPTEPSSPER SPPSPATDQR GGGPNP
Length:1,296
Mass (Da):141,372
Last modified:March 18, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9FB10DA18A26BCAA
GO
Isoform 2 (identifier: Q3V3V9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-603: Missing.
     873-928: VLLRKRNGTP...YQRVDVCVGW → DESSSWKWLE...HHRPPPGGPQ

Show »
Length:738
Mass (Da):79,761
Checksum:iA4F610FE5AF95C58
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
S0DHL8S0DHL8_MOUSE
Capping protein, Arp2/3 and myosin-...
Carmil2 Rltpr
1,397Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0326341 – 603Missing in isoform 2. 1 PublicationAdd BLAST603
Alternative sequenceiVSP_032635873 – 928VLLRK…VCVGW → DESSSWKWLEPSNCFHLVSS LHGAAEEAERDPELAAPGED AEPQAGPSARGSPSPAAPGP PAGPLPRMDLPPAGQPLRHP TRARPRPRRQHHHRPPPGGP Q in isoform 2. 1 PublicationAdd BLAST56

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK031012 mRNA Translation: BAE20471.1
AC152826 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001028492.1, NM_001033320.2

Genome annotation databases

UCSC genome browser

More...
UCSCi
uc009ndo.1, mouse [Q3V3V9-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031012 mRNA Translation: BAE20471.1
AC152826 Genomic DNA No translation available.
RefSeqiNP_001028492.1, NM_001033320.2

3D structure databases

SMRiQ3V3V9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi231561, 3 interactors
IntActiQ3V3V9, 20 interactors

PTM databases

iPTMnetiQ3V3V9
PhosphoSitePlusiQ3V3V9

Proteomic databases

EPDiQ3V3V9
jPOSTiQ3V3V9
PaxDbiQ3V3V9
PeptideAtlasiQ3V3V9
PRIDEiQ3V3V9

Genome annotation databases

UCSCiuc009ndo.1, mouse [Q3V3V9-2]

Organism-specific databases

MGIiMGI:2685431, Carmil2

Phylogenomic databases

HOGENOMiCLU_375944_0_0_1
InParanoidiQ3V3V9
OrthoDBi208951at2759
PhylomeDBiQ3V3V9
TreeFamiTF316381

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
234695, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rltpr, mouse

Protein Ontology

More...
PROi
PR:Q3V3V9
RNActiQ3V3V9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000050357, Expressed in thymus and 86 other tissues
GenevisibleiQ3V3V9, MM

Family and domain databases

Gene3Di2.30.29.30, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR029763, CARMIL2
IPR031943, CARMIL_C
IPR041245, CARMIL_PH
IPR001611, Leu-rich_rpt
IPR032675, LRR_dom_sf
IPR011993, PH-like_dom_sf
PANTHERiPTHR24112:SF32, PTHR24112:SF32, 2 hits
PfamiView protein in Pfam
PF17888, Carm_PH, 1 hit
PF16000, CARMIL_C, 2 hits
PF13516, LRR_6, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCARL2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3V3V9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: October 7, 2020
This is version 105 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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