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Entry version 107 (02 Jun 2021)
Sequence version 1 (11 Oct 2005)
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Protein

Acrosin-binding protein

Gene

Acrbp

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.

1 Publication

Maintains pro-ACR as an enzymatically inactive zymogen in the acrosome until acrosomal exocytosis (PubMed:27303034).

Partially contributes also to the assembly of acrosomal proteins to form an acrosomal granule (PubMed:27303034).

1 Publication

Rodent specific isoform that participates in the formation of the acrosomal granule into the center of the acrosomal vesicle during early spermiogenesis (PubMed:27303034).

In the fertilization process promotes ACR release from the acrosome during acrosomal exocytosis (PubMed:27303034).

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Acrosin-binding protein
Alternative name(s):
Acrosin-binding protein, 60 kDa form
Proacrosin-binding protein sp32
Cleaved into the following chain:
Alternative name(s):
ACRPB-C1 Publication
Acrosin-binding protein, 32 kDa form, mature form
Sp321 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AcrbpImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1859515, Acrbp

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasmic vesicle, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Deficient male and female are normal in behavior, body size, and health condition. Females exhibit normal fertility. However, males exhibit a severely reduced fertility. The acrosomal structure of spermatids is severely deformed at the later steps of spermiogenesis.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000022751726 – 540Acrosin-binding proteinAdd BLAST515
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_000044936926 – 272Removed in mature formBy similarityAdd BLAST247
ChainiPRO_0000449370273 – 540Acrosin-binding protein, mature formAdd BLAST268

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

The N-terminus is blocked.By similarity
Phosphorylated on Tyr residues in capacitated sperm.By similarity
Synthesized as a 60-kDa precursor in pachytene spermatocytes, postmeiotic spermatocytes and haploid spermatids and is processed into the mature protein in elongating spermatids.1 Publication
Degraded in elongating spermatid.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3V140

PeptideAtlas

More...
PeptideAtlasi
Q3V140

PRoteomics IDEntifications database

More...
PRIDEi
Q3V140

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
285940 [Q3V140-1]
285941 [Q3V140-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3V140

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3V140

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis-specific (at protein level). Detected in pachytene spermatocytes and in haploid spermatids and in elongating spermatids.2 Publications
Testis-specific. Detected in pachytene spermatocytes and round spermatids but absent in elongating spermatids. Produced specifically in rodents.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000072770, Expressed in testis and 200 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3V140, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3V140, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds pro-ACR. Does not bind the mature form of ACR.

1 Publication

Binds pro-ACR. Does not bind the mature form of ACR.

1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000085632

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3V140, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 105Pro-ACR binding1 PublicationAdd BLAST80
Regioni183 – 267DisorderedSequence analysisAdd BLAST85
Regioni316 – 424Pro-ACR binding1 PublicationAdd BLAST109

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi194 – 214Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi215 – 232Acidic residuesSequence analysisAdd BLAST18
Compositional biasi241 – 267Polar residuesSequence analysisAdd BLAST27

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R6TS, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000826

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_879871_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3V140

Identification of Orthologs from Complete Genome Data

More...
OMAi
SWLQTEF

Database of Orthologous Groups

More...
OrthoDBi
961418at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3V140

TreeFam database of animal gene trees

More...
TreeFami
TF336597

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009865, Proacrosin-bd

The PANTHER Classification System

More...
PANTHERi
PTHR21362, PTHR21362, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07222, PBP_sp32, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 11 Publication (identifier: Q3V140-1) [UniParc]FASTAAdd to basket
Also known as: ACRBP-W1 Publication

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMNLAAGFLL MLLEVLLLPG TPLSAEESPA STPGSPLSST EYERFFALLT
60 70 80 90 100
PTWKAETTCR LRATHGCRNP TLVQLDQYEN HGLVPDGAVC SDLPYASWFE
110 120 130 140 150
SFCQFAQYRC SNHVYYAKRV RCSQPVSILS PNTLKEVESS AEVPPTSMTT
160 170 180 190 200
PIVSHATATE HQAFQPWPER LNNNVEELLQ SSLSLGGKDQ QSSRRPGQEQ
210 220 230 240 250
RKQEQIQEHK LEEAQEQEEQ EEEEEEEEAK QEEGQGTEAG LESVSRLQSD
260 270 280 290 300
SEPKFQSQSL SSNPSFFTPR VREVESAPLM MKNIQELIRS AQEMDEMNEL
310 320 330 340 350
YDDSWRSQST GSLQQLPHME TLMVLCYSIM ENTCTMTPTA KAWSYMEEEI
360 370 380 390 400
LGFGDSVCDN LGRRHTAACP LCAFCSLKLE QCHSEASVLR QKCDASHKIP
410 420 430 440 450
FISPLLSAQS ISTGNQARIP DKGRFAGLEM YGGLSSEFWC NRLAMKGCED
460 470 480 490 500
DRVSNWLKAE FLSFQEGDFP TKICDTNYIQ YPNYCSFKSQ QCLLRNQNRK
510 520 530 540
MSRMRCMLNE RYNVLSLAKS EEVILRWSQE FSTLAIGQFG
Length:540
Mass (Da):61,141
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i14483661FF5884C4
GO
Isoform 21 Publication (identifier: Q3V140-2) [UniParc]FASTAAdd to basket
Also known as: ACRBP-V51 Publication

The sequence of this isoform differs from the canonical sequence as follows:
     312-316: SLQQL → RYRKL
     317-540: Missing.

Show »
Length:316
Mass (Da):35,787
Checksum:iD91FABB7DBF40DBD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z440F2Z440_MOUSE
Acrosin-binding protein
Acrbp
170Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6P8Q6Q6P8Q6_MOUSE
Acrosin-binding protein
Acrbp Ing4
167Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti195R → I in BAC36445 (PubMed:16141072).Curated1
Sequence conflicti201R → H in BAA04498 (Ref. 1) Curated1
Sequence conflicti201R → H in BAA04499 (Ref. 1) Curated1
Sequence conflicti389L → V in BAA04498 (Ref. 1) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_051965312 – 316SLQQL → RYRKL in isoform 2. 3 Publications5
Alternative sequenceiVSP_051966317 – 540Missing in isoform 2. 3 PublicationsAdd BLAST224

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D17573 mRNA Translation: BAA04498.1
D17574 mRNA Translation: BAA04499.1
AK076691 mRNA Translation: BAC36445.1
AK132705 mRNA Translation: BAE21313.1
BC011079 mRNA Translation: AAH11079.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20542.1 [Q3V140-1]
CCDS51910.1 [Q3V140-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001120812.1, NM_001127340.1 [Q3V140-2]
NP_058541.2, NM_016845.2 [Q3V140-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000088294; ENSMUSP00000085632; ENSMUSG00000072770 [Q3V140-1]
ENSMUST00000112414; ENSMUSP00000108033; ENSMUSG00000072770 [Q3V140-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54137

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:54137

UCSC genome browser

More...
UCSCi
uc009dth.1, mouse [Q3V140-2]
uc009dti.2, mouse [Q3V140-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D17573 mRNA Translation: BAA04498.1
D17574 mRNA Translation: BAA04499.1
AK076691 mRNA Translation: BAC36445.1
AK132705 mRNA Translation: BAE21313.1
BC011079 mRNA Translation: AAH11079.1
CCDSiCCDS20542.1 [Q3V140-1]
CCDS51910.1 [Q3V140-2]
RefSeqiNP_001120812.1, NM_001127340.1 [Q3V140-2]
NP_058541.2, NM_016845.2 [Q3V140-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000085632

PTM databases

iPTMnetiQ3V140
PhosphoSitePlusiQ3V140

Proteomic databases

PaxDbiQ3V140
PeptideAtlasiQ3V140
PRIDEiQ3V140
ProteomicsDBi285940 [Q3V140-1]
285941 [Q3V140-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
48711, 89 antibodies

The DNASU plasmid repository

More...
DNASUi
54137

Genome annotation databases

EnsembliENSMUST00000088294; ENSMUSP00000085632; ENSMUSG00000072770 [Q3V140-1]
ENSMUST00000112414; ENSMUSP00000108033; ENSMUSG00000072770 [Q3V140-2]
GeneIDi54137
KEGGimmu:54137
UCSCiuc009dth.1, mouse [Q3V140-2]
uc009dti.2, mouse [Q3V140-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84519
MGIiMGI:1859515, Acrbp

Phylogenomic databases

eggNOGiENOG502R6TS, Eukaryota
GeneTreeiENSGT00390000000826
HOGENOMiCLU_879871_0_0_1
InParanoidiQ3V140
OMAiSWLQTEF
OrthoDBi961418at2759
PhylomeDBiQ3V140
TreeFamiTF336597

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
54137, 2 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Acrbp, mouse

Protein Ontology

More...
PROi
PR:Q3V140
RNActiQ3V140, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000072770, Expressed in testis and 200 other tissues
ExpressionAtlasiQ3V140, baseline and differential
GenevisibleiQ3V140, MM

Family and domain databases

InterProiView protein in InterPro
IPR009865, Proacrosin-bd
PANTHERiPTHR21362, PTHR21362, 1 hit
PfamiView protein in Pfam
PF07222, PBP_sp32, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACRBP_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3V140
Secondary accession number(s): Q62253
, Q62254, Q8C621, Q91VQ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: October 11, 2005
Last modified: June 2, 2021
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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