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Entry version 77 (12 Aug 2020)
Sequence version 1 (11 Oct 2005)
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Protein

NUT family member 2

Gene

Nutm2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NUT family member 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nutm2Imported
Synonyms:Gm806Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685652, Nutm2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003379961 – 733NUT family member 2Add BLAST733

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q3V0C3

PRoteomics IDEntifications database

More...
PRIDEi
Q3V0C3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3V0C3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3V0C3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000071909, Expressed in spermatid and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000094390

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3V0C3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NUT family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502RU0F, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00410000025793

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_021726_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3V0C3

Identification of Orthologs from Complete Genome Data

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OMAi
QTGMARS

Database of Orthologous Groups

More...
OrthoDBi
425279at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3V0C3

TreeFam database of animal gene trees

More...
TreeFami
TF337728

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024310, NUT
IPR024309, NUT_N

The PANTHER Classification System

More...
PANTHERi
PTHR22879, PTHR22879, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12881, NUT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q3V0C3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLSRQTWLL SKPIGIVSEA SSLGQNMTIN PGASLPTFAT LPVLPPAPQP
60 70 80 90 100
VPQLFWEPPA PLVTAGISPG NPLVLSALPG MPLVAEGGST ALSAAVPLNI
110 120 130 140 150
VQLGTLGQPV QPVHNTNIVL TQVPLTCNIP GTQGVGMGFM TTPAANNFIN
160 170 180 190 200
TRIASTVQPQ EGTWILGPHP PTTQQVVQLV PVKSPVNSAQ PPKGAYGESG
210 220 230 240 250
PANIQTNSPE NYLSKPDSVY GNFRRWQHIK TLVQRHLPQT TDVAAFSCFL
260 270 280 290 300
IPVLRSLARR KPTMNVEEGL WRGLQEWQCT SNYDRMIFYE MAEKFTEFES
310 320 330 340 350
AEEMENSRLE IIRSIQYQVV ATIPRQDPPR LPAPEVAEEP ECTSMKTVHQ
360 370 380 390 400
TDPAHLPELR PQKLQKTETP MEIPPEAVRE YMEIMDWLEG FPQSFTGEAK
410 420 430 440 450
EKEEDENNGP EQEGDDLYSD AELLSYIDEL CSQKHFVEQV EAIINPQFVA
460 470 480 490 500
EILSTKPEID ILALTKVLEH EEELTVDQLL EKPCPALKKR GVERAPPNPG
510 520 530 540 550
APQIPASTSV PSVCQDAERD EHGVQRGASA QTGSSRMASL DQQCLEVTSA
560 570 580 590 600
EIWGPKPATV FPSNQSSPSL VDVRYTGIPR GRGTYNQSPG SRCVRSFRVA
610 620 630 640 650
SAIEDLHRSL ARTIEDKEEL HSLSFLLASQ YRLVPWKVPH QVCPYTDLSD
660 670 680 690 700
SESIPSPCPK LRGLSPDLCS IAKSKKRALF GSLVPMAKRP NLGPGHGVSE
710 720 730
GPLSALELAH LSQPQKRKHE PLGTHKRKRK KRH
Length:733
Mass (Da):80,589
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE49290C86E3688E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK133253 mRNA Translation: BAE21581.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS26507.1

NCBI Reference Sequences

More...
RefSeqi
NP_001028572.1, NM_001033400.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000096633; ENSMUSP00000094390; ENSMUSG00000071909

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
328250

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:328250

UCSC genome browser

More...
UCSCi
uc007qkn.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK133253 mRNA Translation: BAE21581.1
CCDSiCCDS26507.1
RefSeqiNP_001028572.1, NM_001033400.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000094390

PTM databases

iPTMnetiQ3V0C3
PhosphoSitePlusiQ3V0C3

Proteomic databases

PaxDbiQ3V0C3
PRIDEiQ3V0C3

Genome annotation databases

EnsembliENSMUST00000096633; ENSMUSP00000094390; ENSMUSG00000071909
GeneIDi328250
KEGGimmu:328250
UCSCiuc007qkn.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
328250
MGIiMGI:2685652, Nutm2

Phylogenomic databases

eggNOGiENOG502RU0F, Eukaryota
GeneTreeiENSGT00410000025793
HOGENOMiCLU_021726_0_0_1
InParanoidiQ3V0C3
OMAiQTGMARS
OrthoDBi425279at2759
PhylomeDBiQ3V0C3
TreeFamiTF337728

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
328250, 1 hit in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q3V0C3
RNActiQ3V0C3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000071909, Expressed in spermatid and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR024310, NUT
IPR024309, NUT_N
PANTHERiPTHR22879, PTHR22879, 1 hit
PfamiView protein in Pfam
PF12881, NUT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNUTM2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3V0C3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 11, 2005
Last modified: August 12, 2020
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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