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Entry version 100 (08 May 2019)
Sequence version 1 (11 Oct 2005)
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Protein
Submitted name:

Uncharacterized protein

Gene

Fn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fn1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:95566 Fn1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

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PeptideAtlasi
Q3UZF9

PRoteomics IDEntifications database

More...
PRIDEi
Q3UZF9

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini28 – 117Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini118 – 211Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini212 – 303Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini304 – 391Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini392 – 485Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini486 – 572Fibronectin type-IIIInterPro annotationAdd BLAST87
Domaini573 – 663Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini771 – 865Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini872 – 916Fibronectin type-IInterPro annotationAdd BLAST45
Domaini917 – 959Fibronectin type-IInterPro annotationAdd BLAST43
Domaini961 – 1001Fibronectin type-IInterPro annotationAdd BLAST41

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IF4N Eukaryota
ENOG410Y2NH LUCA

KEGG Orthology (KO)

More...
KOi
K05717

Database of Orthologous Groups

More...
OrthoDBi
6580at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00061 FN1, 3 hits
cd00063 FN3, 8 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 8 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000083 Fibronectin_type1
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00039 fn1, 3 hits
PF00041 fn3, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00058 FN1, 3 hits
SM00060 FN3, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01253 FN1_1, 1 hit
PS51091 FN1_2, 3 hits
PS50853 FN3, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q3UZF9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EYLVSVSSVY EQHESIPLRG RQKTGLDSPT GFDSSDITAN SFTVHWVAPR
60 70 80 90 100
APITGYIIRH HAEHSVGRPR QDRVPPSRNS ITLTNLNPGT EYVVSIIAVN
110 120 130 140 150
GREESPPLIG QQATVSDIPR DLEVIASTPT SLLISWEPPA VSVRYYRITY
160 170 180 190 200
GETGGNSPVQ EFTVPGSKST ATINNIKPGA DYTITLYAVT GRGDSPASSK
210 220 230 240 250
PVSINYKTEI DKPSQMQVTD VQDNSISVRW LPSTSPVTGY RVTTTPKNGL
260 270 280 290 300
GPSKTKTASP DQTEMTIEGL QPTVEYVVSV YAQNRNGESQ PLVQTAVTNI
310 320 330 340 350
DRPKGLAFTD VDVDSIKIAW ESPQGQVSRY RVTYSSPEDG IRELFPAPDG
360 370 380 390 400
EDDTAELQGL RPGSEYTVSV VALHDDMESQ PLIGIQSTAI PAPTNLKFSQ
410 420 430 440 450
VTPTSFTAQW IAPSVQLTGY RVRVNPKEKT GPMKEINLSP DSSSVIVSGL
460 470 480 490 500
MVATKYEVSV YALKDTLTSR PAQGVITTLE NVSPPRRARV TDATETTITI
510 520 530 540 550
SWRTKTETIT GFQVDAIPAN GQTPVQRSIS PDVRSYTITG LQPGTDYKIH
560 570 580 590 600
LYTLNDNARS SPVIIDASTA IDAPSNLRFL TTTPNSLLVS WQAPRARITG
610 620 630 640 650
YIIKYEKPGS PPREVVPRPR PGVTEATITG LEPGTEYTIY VIALKNNQKS
660 670 680 690 700
EPLIGRKKTD ELPQLVTLPH PNLHGPEILD VPSTVQKTPF ITNPGYDTEN
710 720 730 740 750
GIQLPGTTHQ QPSVGQQMIF EEHGFRRTTP PTAATPVRLR PRPYLPNVDE
760 770 780 790 800
EVQIGHVPRG DVDYHLYPHV PGLNPNASTG QEALSQTTIS WTPFQESSEY
810 820 830 840 850
IISCQPVGTD EEPLQFQVPG TSTSATLTGL TRGVTYNIIV EALQNQRRHK
860 870 880 890 900
VREEVVTVGN AVSEGLNQPT DDSCFDPYTV SHYAIGEEWE RLSDAGFKLT
910 920 930 940 950
CQCLGFGSGH FRCDSSKWCH DNGVNYKIGE KWDRQGENGQ RMSCTCLGNG
960 970 980 990 1000
KGEFKCDPHE ATCYDDGKTY HVGEQWQKEY LGAICSCTCF GGQRGWRCDN
1010 1020 1030 1040 1050
CRRPGAAEPS PDGTTGHTYN QYTQRYNQRT NTNVNCPIEC FMPLDVQADR

DDSRE
Length:1,055
Mass (Da):115,893
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA92CF245686F382E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK133868 mRNA Translation: BAE21898.1

NCBI Reference Sequences

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RefSeqi
NP_034363.1, NM_010233.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
14268

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:14268

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK133868 mRNA Translation: BAE21898.1
RefSeqiNP_034363.1, NM_010233.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiQ3UZF9
PRIDEiQ3UZF9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi14268
KEGGimmu:14268

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2335
MGIiMGI:95566 Fn1

Phylogenomic databases

eggNOGiENOG410IF4N Eukaryota
ENOG410Y2NH LUCA
KOiK05717
OrthoDBi6580at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Fn1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

CDDicd00061 FN1, 3 hits
cd00063 FN3, 8 hits
Gene3Di2.60.40.10, 8 hits
InterProiView protein in InterPro
IPR000083 Fibronectin_type1
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF00039 fn1, 3 hits
PF00041 fn3, 8 hits
SMARTiView protein in SMART
SM00058 FN1, 3 hits
SM00060 FN3, 8 hits
SUPFAMiSSF49265 SSF49265, 5 hits
PROSITEiView protein in PROSITE
PS01253 FN1_1, 1 hit
PS51091 FN1_2, 3 hits
PS50853 FN3, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ3UZF9_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3UZF9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 8, 2019
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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