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Protein
Submitted name:

Angiotensinogen

Gene

Agt

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins
R-MMU-375276 Peptide ligand-binding receptors
R-MMU-416476 G alpha (q) signalling events
R-MMU-418594 G alpha (i) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
AngiotensinogenImported
Gene namesi
Name:AgtImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:87963 Agt

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000031980 Expressed in 179 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 478SERPINInterPro annotationAdd BLAST368

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00890000139531
HOGENOMiHOG000033941
HOVERGENiHBG004233
KOiK09821
OMAiRFMQAVT
OrthoDBiEOG091G077M
TreeFamiTF343201

Family and domain databases

InterProiView protein in InterPro
IPR000227 Angiotensinogen
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PTHR11461:SF13 PTHR11461:SF13, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
PRINTSiPR00654 ANGIOTENSNGN
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q3UTR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHRSEMTPTG AGLKATIFCI LTWVSLTAGD RVYIHPFHLL YHNKSTCAQL
60 70 80 90 100
ENPSVETLPE STFEPVPIQA KTSPVNEKTL HDQLVLAAEK LEDEDRKRAA
110 120 130 140 150
QVAMIANFVG FRMYKMLNEA GSGASGAILS PPALFGTLVS FYLGSLDPTA
160 170 180 190 200
SQLQTLLDVP VKEGDCTSRL DGHKVLAALR AIQGLLVTQG GSSSQTPLLQ
210 220 230 240 250
SIVVGLFTAP GFRLKHSFVQ SLALFTPALF PRSLDLSTDP VLATEKINRF
260 270 280 290 300
IKAVTGWKMN LPLEGVSTDS TLLFNTYVHF QGTMRGFSQL PGVHEFWVDN
310 320 330 340 350
SISVSVPMIS GTGNFQHWSD TQNNFSVTCV PLGERATLLL IQPHCTSDLD
360 370 380 390 400
RVEALIFRND LLTWIENPPP RAIRLTLPQL EIRGSYNLQD LLAEDKLPTL
410 420 430 440 450
LGAEANLNNI GDTNPRVGEV LNSILLELKA GEEEQPTTSV QQPGSPEALD
460 470 480
VTLSSPFLFA IYEQDSGTLH FLGRVNNPQS VV
Length:482
Mass (Da):52,670
Last modified:October 11, 2005 - v1
Checksum:iDC4633B4020178C9
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P11859ANGT_MOUSE
Angiotensinogen
Agt Serpina8
477Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126930 Genomic DNA No translation available.
AK139179 mRNA Translation: BAE23913.1
RefSeqiNP_031454.3, NM_007428.3
UniGeneiMm.301626

Genome annotation databases

EnsembliENSMUST00000063278; ENSMUSP00000066488; ENSMUSG00000031980
GeneIDi11606
KEGGimmu:11606
UCSCiuc009nxe.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126930 Genomic DNA No translation available.
AK139179 mRNA Translation: BAE23913.1
RefSeqiNP_031454.3, NM_007428.3
UniGeneiMm.301626

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000063278; ENSMUSP00000066488; ENSMUSG00000031980
GeneIDi11606
KEGGimmu:11606
UCSCiuc009nxe.1 mouse

Organism-specific databases

CTDi183
MGIiMGI:87963 Agt

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00890000139531
HOGENOMiHOG000033941
HOVERGENiHBG004233
KOiK09821
OMAiRFMQAVT
OrthoDBiEOG091G077M
TreeFamiTF343201

Enzyme and pathway databases

ReactomeiR-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins
R-MMU-375276 Peptide ligand-binding receptors
R-MMU-416476 G alpha (q) signalling events
R-MMU-418594 G alpha (i) signalling events

Miscellaneous databases

ChiTaRSiMgmt mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031980 Expressed in 179 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR000227 Angiotensinogen
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PTHR11461:SF13 PTHR11461:SF13, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
PRINTSiPR00654 ANGIOTENSNGN
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UTR7_MOUSE
AccessioniPrimary (citable) accession number: Q3UTR7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 12, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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