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Protein
Submitted name:

Uncharacterized protein

Gene

Scn9a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Scn9aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107636 Scn9a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei122 – 145HelicalSequence analysisAdd BLAST24
Transmembranei190 – 209HelicalSequence analysisAdd BLAST20
Transmembranei221 – 242HelicalSequence analysisAdd BLAST22
Transmembranei248 – 268HelicalSequence analysisAdd BLAST21
Transmembranei378 – 405HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ3UQV9

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 411Ion_transInterPro annotationAdd BLAST287

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili402 – 447Sequence analysisAdd BLAST46

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG091796

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR028803 SCN9A
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF221 PTHR10037:SF221, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit

Sequencei

Sequence statusi: Fragment.

Q3UQV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMLPPPGPQ SFVHFTKQSL ALIEQRISEE KAKGHKDEKK DDEEEGPKPS
60 70 80 90 100
SDLEAGKQLP FIYGDIPPGM VSEPLEDLDP YYADKKTFIV LNKGKAIFRF
110 120 130 140 150
NATPALYMLS PFSPLRRISI KILVHSLFSM LIMCTILTNC IFMTMSNPPD
160 170 180 190 200
WTKNVEYTFT GIYTFESLIK ILARGFCVGE FTFLRDPWNW LDFVVIVFAY
210 220 230 240 250
LTEFVNLGNV SALRTFRVLR ALKTISVIPG LKTIVGALIQ SVKKLSDVMI
260 270 280 290 300
LTVFCLSVFA LIGLQLFMGN LKHKCFRKDL EQNETLESIM STAESEEELK
310 320 330 340 350
RYFYYLEGSK DALLCGFSTD SGQCPEGYEC VTAGRNPDYG YTSFDTFGWA
360 370 380 390 400
FLALFRLMTQ DYWENLYQQT LRAAGKTYMI FFVVVIFLGS FYLINLILAV
410 420 430 440 450
VAMAYEEQNQ ANIEEAKQKE LEFQQMLDRL KKEQEEAEAI AAAAAEYTSL
460 470
GRSRIMGLSE SSSETSRLSS KSAKERRN
Length:478
Mass (Da):54,294
Last modified:October 11, 2005 - v1
Checksum:iF09DFDB6820650EF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei478Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK142068 mRNA Translation: BAE24929.1
UniGeneiMm.440889

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK142068 mRNA Translation: BAE24929.1
UniGeneiMm.440889

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ3UQV9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:107636 Scn9a

Phylogenomic databases

HOVERGENiHBG091796

Miscellaneous databases

ChiTaRSiScn9a mouse
SOURCEiSearch...

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR028803 SCN9A
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF221 PTHR10037:SF221, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UQV9_MOUSE
AccessioniPrimary (citable) accession number: Q3UQV9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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