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Protein

Transmembrane protein 26

Gene

Tmem26

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 26
Gene namesi
Name:Tmem26
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:2143537 Tmem26

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei36 – 56HelicalSequence analysisAdd BLAST21
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Transmembranei138 – 158HelicalSequence analysisAdd BLAST21
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Transmembranei208 – 228HelicalSequence analysisAdd BLAST21
Transmembranei258 – 278HelicalSequence analysisAdd BLAST21
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002458661 – 366Transmembrane protein 26Add BLAST366

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi110N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ3UP23
PRIDEiQ3UP23

PTM databases

iPTMnetiQ3UP23
PhosphoSitePlusiQ3UP23

Expressioni

Gene expression databases

BgeeiENSMUSG00000060044 Expressed in 153 organ(s), highest expression level in embryo
CleanExiMM_TMEM26
ExpressionAtlasiQ3UP23 baseline and differential
GenevisibleiQ3UP23 MM

Interactioni

Protein-protein interaction databases

BioGridi236485, 1 interactor
STRINGi10090.ENSMUSP00000079789

Structurei

3D structure databases

ProteinModelPortaliQ3UP23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4610 Eukaryota
ENOG410XS6J LUCA
GeneTreeiENSGT00390000014794
HOGENOMiHOG000047342
HOVERGENiHBG060870
InParanoidiQ3UP23
OMAiQYSADLW
OrthoDBiEOG091G0BYS
PhylomeDBiQ3UP23
TreeFamiTF314156

Family and domain databases

InterProiView protein in InterPro
IPR019169 Transmembrane_26
PANTHERiPTHR22168 PTHR22168, 1 hit
PfamiView protein in Pfam
PF09772 Tmem26, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q3UP23-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGLVLLKAL VTRLLFLLHS LVAVWRVTWV KEEHRYWLLA LLNLLLVLET
60 70 80 90 100
VLTLKFKRGR GYKWLSPAIF VYLVNIMPSL WLLEMHHGNQ YCSTQSERMA
110 120 130 140 150
QNFSRRGDVN QTLSSHRATN GMGNILELAR GFVDNLSMVC EPVWTLGLHQ
160 170 180 190 200
TLLLILIIGR WLLPIGGTIT RDQLSELLLM FVGTAADILE FTTETLKENN
210 220 230 240 250
VRTNPTLVSG ILVVWTWSML QFPLDLAVQL KLVCPASVKA RGFLRVFLCQ
260 270 280 290 300
YSADLWAIGL SFFIQDGPFL VVRLVLMIYF KVINHMLVFF AVKNSLVMAL
310 320 330 340 350
HFYRLVALIM ATRDFMRDHP ESPKPEHSGP DQPSESGPSE WEDASPEALP
360
LRTSPVTSEE SYPTTP
Length:366
Mass (Da):41,637
Last modified:July 11, 2006 - v2
Checksum:iBF62E559BB0EE534
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1W2P8C1A0A1W2P8C1_MOUSE
Transmembrane protein 26
Tmem26
64Annotation score:
A0A1W2P745A0A1W2P745_MOUSE
Transmembrane protein 26
Tmem26
123Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti45L → M in BAE25574 (PubMed:16141072).Curated1
Sequence conflicti49E → D in BAC39167 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK143866 mRNA Translation: BAE25574.1
AK084351 mRNA Translation: BAC39167.1
BC117503 mRNA Translation: AAI17504.1
CCDSiCCDS23906.1
RefSeqiNP_808462.2, NM_177794.3
UniGeneiMm.2479

Genome annotation databases

EnsembliENSMUST00000080995; ENSMUSP00000079789; ENSMUSG00000060044
GeneIDi327766
KEGGimmu:327766
UCSCiuc007fmm.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK143866 mRNA Translation: BAE25574.1
AK084351 mRNA Translation: BAC39167.1
BC117503 mRNA Translation: AAI17504.1
CCDSiCCDS23906.1
RefSeqiNP_808462.2, NM_177794.3
UniGeneiMm.2479

3D structure databases

ProteinModelPortaliQ3UP23
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi236485, 1 interactor
STRINGi10090.ENSMUSP00000079789

PTM databases

iPTMnetiQ3UP23
PhosphoSitePlusiQ3UP23

Proteomic databases

PaxDbiQ3UP23
PRIDEiQ3UP23

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000080995; ENSMUSP00000079789; ENSMUSG00000060044
GeneIDi327766
KEGGimmu:327766
UCSCiuc007fmm.2 mouse

Organism-specific databases

CTDi219623
MGIiMGI:2143537 Tmem26

Phylogenomic databases

eggNOGiKOG4610 Eukaryota
ENOG410XS6J LUCA
GeneTreeiENSGT00390000014794
HOGENOMiHOG000047342
HOVERGENiHBG060870
InParanoidiQ3UP23
OMAiQYSADLW
OrthoDBiEOG091G0BYS
PhylomeDBiQ3UP23
TreeFamiTF314156

Miscellaneous databases

PROiPR:Q3UP23
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000060044 Expressed in 153 organ(s), highest expression level in embryo
CleanExiMM_TMEM26
ExpressionAtlasiQ3UP23 baseline and differential
GenevisibleiQ3UP23 MM

Family and domain databases

InterProiView protein in InterPro
IPR019169 Transmembrane_26
PANTHERiPTHR22168 PTHR22168, 1 hit
PfamiView protein in Pfam
PF09772 Tmem26, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTMM26_MOUSE
AccessioniPrimary (citable) accession number: Q3UP23
Secondary accession number(s): Q149T3, Q8BN94
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: July 11, 2006
Last modified: September 12, 2018
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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