UniProtKB - Q3UNF2 (Q3UNF2_MOUSE)
Protein
Serine/threonine-protein phosphatase
Gene
Ppp4c
Organism
Mus musculus (Mouse)
Status
Functioni
Catalytic activityi
- EC:3.1.3.16UniRule annotation
GO - Molecular functioni
- protein serine phosphatase activity Source: UniProtKB-EC
- protein threonine phosphatase activity Source: UniProtKB-EC
GO - Biological processi
Keywordsi
Molecular function | Hydrolase, Protein phosphataseARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation) |
Gene namesi | Name:Ppp4cImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1891763, Ppp4c |
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
Plasma Membrane
- plasma membrane Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000030697, Expressed in mandibular prominence and 313 other tissues |
Family & Domainsi
Sequence similaritiesi
Belongs to the PPP phosphatase family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_004962_8_1_1 |
OMAi | QILWNDP |
OrthoDBi | 808922at2759 |
Family and domain databases
Gene3Di | 3.60.21.10, 1 hit |
InterProi | View protein in InterPro IPR004843, Calcineurin-like_PHP_ApaH IPR029052, Metallo-depent_PP-like IPR006186, Ser/Thr-sp_prot-phosphatase |
Pfami | View protein in Pfam PF00149, Metallophos, 1 hit |
PRINTSi | PR00114, STPHPHTASE |
SMARTi | View protein in SMART SM00156, PP2Ac, 1 hit |
PROSITEi | View protein in PROSITE PS00125, SER_THR_PHOSPHATASE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3UNF2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEISDLDRQ IEQLRRCELI KESEVKALCA KAREILVEES NVQRVDSPVT
60 70 80 90 100
VCGDIHGQFY DLKELFRVGG DVPETNYLFM GDFVDRGFYS VETFLLLLAL
110 120 130 140 150
KVRYPDRITL IRGNHESRQI TQVYGFYDEC LRKYGSVTVW RYCTEIFDYL
160 170 180 190 200
SLSAIIDGKI FCVHGGLSPS IQTLDQIRTI DRKQEVPHDG PMCDLLWSDP
210 220 230 240 250
EDTTGWGVSP RGAGYLFGSD VVAQFNAAND IDMICRAHQL VMEGYKWHFN
260 270 280 290 300
ETVLTVWSAP NYCYRCGNVA AILELDEHLQ KDFIIFEAAP QETRGIPSKK
PVADYFL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK144244 mRNA Translation: BAE25795.1 |
RefSeqi | NP_062648.1, NM_019674.3 |
Genome annotation databases
GeneIDi | 56420 |
KEGGi | mmu:56420 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK144244 mRNA Translation: BAE25795.1 |
RefSeqi | NP_062648.1, NM_019674.3 |
3D structure databases
SMRi | Q3UNF2 |
ModBasei | Search... |
Proteomic databases
EPDi | Q3UNF2 |
MaxQBi | Q3UNF2 |
PRIDEi | Q3UNF2 |
Protocols and materials databases
Antibodypediai | 26991, 418 antibodies |
DNASUi | 56420 |
Genome annotation databases
GeneIDi | 56420 |
KEGGi | mmu:56420 |
Organism-specific databases
CTDi | 5531 |
MGIi | MGI:1891763, Ppp4c |
Phylogenomic databases
HOGENOMi | CLU_004962_8_1_1 |
OMAi | QILWNDP |
OrthoDBi | 808922at2759 |
Miscellaneous databases
BioGRID-ORCSi | 56420, 24 hits in 51 CRISPR screens |
ChiTaRSi | Ppp4c, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030697, Expressed in mandibular prominence and 313 other tissues |
Family and domain databases
Gene3Di | 3.60.21.10, 1 hit |
InterProi | View protein in InterPro IPR004843, Calcineurin-like_PHP_ApaH IPR029052, Metallo-depent_PP-like IPR006186, Ser/Thr-sp_prot-phosphatase |
Pfami | View protein in Pfam PF00149, Metallophos, 1 hit |
PRINTSi | PR00114, STPHPHTASE |
SMARTi | View protein in SMART SM00156, PP2Ac, 1 hit |
PROSITEi | View protein in PROSITE PS00125, SER_THR_PHOSPHATASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3UNF2_MOUSE | |
Accessioni | Q3UNF2Primary (citable) accession number: Q3UNF2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | April 7, 2021 | |
This is version 137 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |