UniProtKB - Q3UN31 (Q3UN31_MOUSE)
Protein
Submitted name:
Phospholipase A2, group VI, isoform CRA_d
Gene
Pla2g6
Organism
Mus musculus (Mouse)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 465 | NucleophilePROSITE-ProRule annotation | 1 | |
Active sitei | 598 | Proton acceptorPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- hydrolase activity Source: UniProtKB-UniRule
GO - Biological processi
- lipid catabolic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | HydrolasePROSITE-ProRule annotation |
Biological process | Lipid degradationPROSITE-ProRule annotation, Lipid metabolism |
Names & Taxonomyi
Protein namesi | Submitted name: Phospholipase A2, group VI, isoform CRA_dImported |
Gene namesi | Name:Pla2g6Imported ORF Names:mCG_128876Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1859152 Pla2g6 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000042632 Expressed in 270 organ(s), highest expression level in testis |
ExpressionAtlasi | Q3UN31 baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 151 – 392 | ANK_REP_REGIONInterPro annotationAdd BLAST | 242 | |
Repeati | 151 – 184 | ANKPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 219 – 251 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 316 – 348 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 349 – 381 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Domaini | 427 – 611 | PNPLAInterPro annotationAdd BLAST | 185 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 431 – 436 | GXGXXGPROSITE-ProRule annotation | 6 | |
Motifi | 463 – 467 | GXSXGPROSITE-ProRule annotation | 5 | |
Motifi | 598 – 600 | DGA/GPROSITE-ProRule annotation | 3 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationPhylogenomic databases
KOi | K16343 |
OrthoDBi | 841851at2759 |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR016035 Acyl_Trfase/lysoPLipase IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR002641 PNPLA_dom |
Pfami | View protein in Pfam PF12796 Ank_2, 2 hits PF01734 Patatin, 1 hit |
PRINTSi | PR01415 ANKYRIN |
SMARTi | View protein in SMART SM00248 ANK, 6 hits |
SUPFAMi | SSF48403 SSF48403, 1 hit SSF52151 SSF52151, 1 hit |
PROSITEi | View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 4 hits PS51635 PNPLA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3UN31-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQFFGRLVNT LSSVTNLFSN PFRVKEVSLT DYVSSERVRE EGQLILLQNV
60 70 80 90 100
SNRTWDCVLV SPRNPQSGFR LFQLESEADA LVNFQQFSSQ LPPFYESSVQ
110 120 130 140 150
VLHVEVLQHL TDLIRNHPSW TVTHLAVELG IRECFHHSRI ISCANSTENE
160 170 180 190 200
EGCTPLHLAC RKGDSEILVE LVQYCHAQMD VTDNKGETAF HYAVQGDNPQ
210 220 230 240 250
VLQLLGKNAS AGLNQVNNQG LTPLHLACKM GKQEMVRVLL LCNARCNIMG
260 270 280 290 300
PGGFPIHTAM KFSQKGCAEM IISMDSNQIH SKDPRYGASP LHWAKNAEMA
310 320 330 340 350
RMLLKRGCDV DSTSSSGNTA LHVAVMRNRF DCVMVLLTYG ANAGARGEHG
360 370 380 390 400
NTPLHLAMSK DNMEMVKALI VFGAEVDTPN DFGETPALIA SKISKQLQDL
410 420 430 440 450
MPISRARKPA FILSSMRDEK RSHDHLLCLD GGGVKGLVII QLLIAIEKAS
460 470 480 490 500
GVATKDLFDW VAGTSTGGIL ALAILHSKSM AYMRGVYFRM KDEVFRGSRP
510 520 530 540 550
YESGPLEEFL KREFGEHTKM TDVKKPKVML TGTLSDRQPA ELHLFRNYDA
560 570 580 590 600
PEAVREPRCN QNINLKPPTQ PADQLVWRAA RSSGAAPTYF RPNGRFLDGG
610 620 630 640 650
LLANNPTLDA MTEIHEYNQD MIRKGQGNKV KKLSIVVSLG TGKSPQVPVT
660 670 680 690 700
CVDVFRPSNP WELAKTVFGA KELGKMVVDC CTDPDGRAVD RARAWCEMVG
710 720 730 740 750
IQYFRLNPQL GSDIMLDEVS DAVLVNALWE TEVYIYEHRE EFQKLVQLLL
SP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK144495 mRNA Translation: BAE25917.1 CH466550 Genomic DNA Translation: EDL04659.1 |
RefSeqi | NP_001185952.1, NM_001199023.1 NP_001185953.1, NM_001199024.1 NP_001185954.1, NM_001199025.1 NP_058611.1, NM_016915.4 XP_017172187.1, XM_017316698.1 |
Genome annotation databases
GeneIDi | 53357 |
KEGGi | mmu:53357 |
UCSCi | uc007wte.2 mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK144495 mRNA Translation: BAE25917.1 CH466550 Genomic DNA Translation: EDL04659.1 |
RefSeqi | NP_001185952.1, NM_001199023.1 NP_001185953.1, NM_001199024.1 NP_001185954.1, NM_001199025.1 NP_058611.1, NM_016915.4 XP_017172187.1, XM_017316698.1 |
3D structure databases
SMRi | Q3UN31 |
ModBasei | Search... |
Proteomic databases
MaxQBi | Q3UN31 |
Genome annotation databases
GeneIDi | 53357 |
KEGGi | mmu:53357 |
UCSCi | uc007wte.2 mouse |
Organism-specific databases
CTDi | 8398 |
MGIi | MGI:1859152 Pla2g6 |
Phylogenomic databases
KOi | K16343 |
OrthoDBi | 841851at2759 |
Miscellaneous databases
ChiTaRSi | Pla2g6 mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000042632 Expressed in 270 organ(s), highest expression level in testis |
ExpressionAtlasi | Q3UN31 baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.20, 2 hits |
InterProi | View protein in InterPro IPR016035 Acyl_Trfase/lysoPLipase IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR002641 PNPLA_dom |
Pfami | View protein in Pfam PF12796 Ank_2, 2 hits PF01734 Patatin, 1 hit |
PRINTSi | PR01415 ANKYRIN |
SMARTi | View protein in SMART SM00248 ANK, 6 hits |
SUPFAMi | SSF48403 SSF48403, 1 hit SSF52151 SSF52151, 1 hit |
PROSITEi | View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 4 hits PS51635 PNPLA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3UN31_MOUSE | |
Accessioni | Q3UN31Primary (citable) accession number: Q3UN31 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | October 16, 2019 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |