Pla2g6

Functionⁱ

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	465	NucleophilePROSITE-ProRule annotation		1
Active siteⁱ	598	Proton acceptorPROSITE-ProRule annotation		1

GO - Molecular functionⁱ

hydrolase activity Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

lipid catabolic process Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	HydrolasePROSITE-ProRule annotation
Biological process	Lipid degradationPROSITE-ProRule annotation, Lipid metabolism

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Phospholipase A2, group VI, isoform CRA_dImported
Gene namesⁱ	Name:Pla2g6Imported ORF Names:mCG_128876Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:1859152 Pla2g6

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000042632 Expressed in 270 organ(s), highest expression level in testis

Bgeeⁱ

ENSMUSG00000042632 Expressed in 270 organ(s), highest expression level in testis

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	151 – 392	ANK_REP_REGIONInterPro annotationAdd BLAST	242
Repeatⁱ	151 – 184	ANKPROSITE-ProRule annotationAdd BLAST	34
Repeatⁱ	219 – 251	ANKPROSITE-ProRule annotationAdd BLAST	33
Repeatⁱ	316 – 348	ANKPROSITE-ProRule annotationAdd BLAST	33
Repeatⁱ	349 – 381	ANKPROSITE-ProRule annotationAdd BLAST	33
Domainⁱ	427 – 611	PNPLAInterPro annotationAdd BLAST	185

Motif

Feature key	Position(s)	DescriptionActions	Length
Motifⁱ	431 – 436	GXGXXGPROSITE-ProRule annotation	6
Motifⁱ	463 – 467	GXSXGPROSITE-ProRule annotation	5
Motifⁱ	598 – 600	DGA/GPROSITE-ProRule annotation	3

Keywords - Domainⁱ

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

HOVERGENⁱ	HBG053482
KEGG Orthology (KO) More...KOⁱ	K16343

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00204 ANK, 2 hits
Gene3Dⁱ	1.25.40.20, 2 hits
InterProⁱ	View protein in InterPro IPR016035 Acyl_Trfase/lysoPLipase IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR002641 PNPLA_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12796 Ank_2, 2 hits PF13606 Ank_3, 1 hit PF01734 Patatin, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 6 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit SSF52151 SSF52151, 1 hit
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 4 hits PS51635 PNPLA, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3UN31-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MQFFGRLVNT LSSVTNLFSN PFRVKEVSLT DYVSSERVRE EGQLILLQNV 
        60         70         80         90        100
SNRTWDCVLV SPRNPQSGFR LFQLESEADA LVNFQQFSSQ LPPFYESSVQ 
       110        120        130        140        150
VLHVEVLQHL TDLIRNHPSW TVTHLAVELG IRECFHHSRI ISCANSTENE 
       160        170        180        190        200
EGCTPLHLAC RKGDSEILVE LVQYCHAQMD VTDNKGETAF HYAVQGDNPQ 
       210        220        230        240        250
VLQLLGKNAS AGLNQVNNQG LTPLHLACKM GKQEMVRVLL LCNARCNIMG 
       260        270        280        290        300
PGGFPIHTAM KFSQKGCAEM IISMDSNQIH SKDPRYGASP LHWAKNAEMA 
       310        320        330        340        350
RMLLKRGCDV DSTSSSGNTA LHVAVMRNRF DCVMVLLTYG ANAGARGEHG 
       360        370        380        390        400
NTPLHLAMSK DNMEMVKALI VFGAEVDTPN DFGETPALIA SKISKQLQDL 
       410        420        430        440        450
MPISRARKPA FILSSMRDEK RSHDHLLCLD GGGVKGLVII QLLIAIEKAS 
       460        470        480        490        500
GVATKDLFDW VAGTSTGGIL ALAILHSKSM AYMRGVYFRM KDEVFRGSRP 
       510        520        530        540        550
YESGPLEEFL KREFGEHTKM TDVKKPKVML TGTLSDRQPA ELHLFRNYDA 
       560        570        580        590        600
PEAVREPRCN QNINLKPPTQ PADQLVWRAA RSSGAAPTYF RPNGRFLDGG 
       610        620        630        640        650
LLANNPTLDA MTEIHEYNQD MIRKGQGNKV KKLSIVVSLG TGKSPQVPVT 
       660        670        680        690        700
CVDVFRPSNP WELAKTVFGA KELGKMVVDC CTDPDGRAVD RARAWCEMVG 
       710        720        730        740        750
IQYFRLNPQL GSDIMLDEVS DAVLVNALWE TEVYIYEHRE EFQKLVQLLL 

SP

Length:752

Mass (Da):83,702

Last modified:October 11, 2005 - v1

Checksum:ⁱAAC3347B0E1292E9

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK144495 mRNA Translation: BAE25917.1 CH466550 Genomic DNA Translation: EDL04659.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001185952.1, NM_001199023.1 NP_001185953.1, NM_001199024.1 NP_001185954.1, NM_001199025.1 NP_058611.1, NM_016915.4 XP_017172187.1, XM_017316698.1
UniGeneⁱ	Mm.155620

Genome annotation databases

GeneIDⁱ	53357
KEGGⁱ	mmu:53357
UCSC genome browser More...UCSCⁱ	uc007wte.2 mouse

Protein	Similar proteins		Species	Score	Length	Source
Q3UN31	Isoform SH-iPLA2 of 85/88 kDa calcium-independent phospholipase A2		HUMAN		752	UniRef90_O60733-2
Uncharacterized protein		FELCA		784
85/88 kDa calcium-independent phospholipase A2 isoform X1		Yangtze finless porpoise		782
85/88 kDa calcium-independent phospholipase A2 isoform X2		Florida manatee		782
85/88 kDa calcium-independent phospholipase A2 isoform X3		BALAS		782
+104

Protein	Similar proteins		Species	Score	Length	Source
Q3UN31	Isoform SH-iPLA2 of 85/88 kDa calcium-independent phospholipase A2		HUMAN		752	UniRef50_O60733-2
Uncharacterized protein		FELCA		784
85/88 kDa calcium-independent phospholipase A2 isoform X2		Florida manatee		782
Uncharacterized protein		AOTNA		782
Uncharacterized protein		PIG		782
+104

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK144495 mRNA Translation: BAE25917.1 CH466550 Genomic DNA Translation: EDL04659.1
RefSeqⁱ	NP_001185952.1, NM_001199023.1 NP_001185953.1, NM_001199024.1 NP_001185954.1, NM_001199025.1 NP_058611.1, NM_016915.4 XP_017172187.1, XM_017316698.1
UniGeneⁱ	Mm.155620

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	53357
KEGGⁱ	mmu:53357
UCSCⁱ	uc007wte.2 mouse

Organism-specific databases

CTDⁱ	8398
MGIⁱ	MGI:1859152 Pla2g6

Phylogenomic databases

HOVERGENⁱ	HBG053482
KOⁱ	K16343

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000042632 Expressed in 270 organ(s), highest expression level in testis

Bgeeⁱ

ENSMUSG00000042632 Expressed in 270 organ(s), highest expression level in testis

Family and domain databases

CDDⁱ	cd00204 ANK, 2 hits
Gene3Dⁱ	1.25.40.20, 2 hits
InterProⁱ	View protein in InterPro IPR016035 Acyl_Trfase/lysoPLipase IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR002641 PNPLA_dom
Pfamⁱ	View protein in Pfam PF12796 Ank_2, 2 hits PF13606 Ank_3, 1 hit PF01734 Patatin, 1 hit
PRINTSⁱ	PR01415 ANKYRIN
SMARTⁱ	View protein in SMART SM00248 ANK, 6 hits
SUPFAMⁱ	SSF48403 SSF48403, 1 hit SSF52151 SSF52151, 1 hit
PROSITEⁱ	View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 4 hits PS51635 PNPLA, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q3UN31_MOUSE
Accessionⁱ	Q3UN31Primary (citable) accession number: Q3UN31
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 11, 2005
	Last sequence update:	October 11, 2005
	Last modified:	October 10, 2018
	This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q3UN31 (Q3UN31_MOUSE)

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Phospholipase A2, group VI, isoform CRA_d

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Functionⁱ

Sites

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Motif

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

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Supporting data

UniProtKB - Q3UN31 (Q3UN31_MOUSE)

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Phospholipase A2, group VI, isoform CRA_d

Pla2g6

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Motif

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Expressionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ