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Entry version 111 (10 Feb 2021)
Sequence version 1 (11 Oct 2005)
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Protein

Activating transcription factor 7-interacting protein 2

Gene

Atf7ip2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (By similarity).By similarity

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Activating transcription factor 7-interacting protein 2
Alternative name(s):
MBD1-containing chromatin-associated factor 2
Protein similar to MCAF2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Atf7ip2
Synonyms:Mcaf2, Psm2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1922579, Atf7ip2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002817851 – 452Activating transcription factor 7-interacting protein 2Add BLAST452

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei184PhosphoserineBy similarity1
Modified residuei257PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3UL97

PRoteomics IDEntifications database

More...
PRIDEi
Q3UL97

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3UL97

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in testis.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in early mouse embryo, especially in the embryonic gonad from 11.5 dpc. Continuously expressed from newborn testis to adult.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000039200, Expressed in spermatocyte and 116 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3UL97, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3UL97, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with MBD1, SETDB1 and SP1. Probably forms a complex with SETDB1 and MBD1 (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000036731

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3UL97, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini346 – 450Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST105

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MCAF family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S2DM, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063707

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_025197_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3UL97

Identification of Orthologs from Complete Genome Data

More...
OMAi
TCHLSQN

Database of Orthologous Groups

More...
OrthoDBi
646436at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3UL97

TreeFam database of animal gene trees

More...
TreeFami
TF329427

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026085, ATF7-int
IPR026089, ATF7-int_2
IPR031870, ATF7IP_BD
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold

The PANTHER Classification System

More...
PANTHERi
PTHR23210, PTHR23210, 2 hits
PTHR23210:SF23, PTHR23210:SF23, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16788, ATF7IP_BD, 1 hit
PF16794, fn3_4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265, SSF49265, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q3UL97-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESPDRKRQK VLKAKKTMPT SYQKQLEILN KSTNVEAPKT TVGTNIPNGH
60 70 80 90 100
NQKMFSKNKE NVKVMKVSEQ INENACGALE RHTALLEQVK HWIRQEICMI
110 120 130 140 150
NCNLFDKKLN ELNERIGKTQ CKSRHEAIAG ELFVKIRRLQ KRIKTVLSSQ
160 170 180 190 200
RNCLEPNTLP SNTVCKVTDS EAMNLNVTQK SVKSRSKRIS SVNHTPLNSS
210 220 230 240 250
EKAGRKTNLP STCVEFASES NTDDVMLISV KNSNLTTSIT SEQTEIRKNT
260 270 280 290 300
SRNLSNSPNS MIKVGPVEKK FDFVIDLTRE GPSNYSIESP SFTLKSTSKA
310 320 330 340 350
VLRSKEIIPV AENGNEGFGS FEHLPPLPEP PAPLPEMADK IKDTLPPQKP
360 370 380 390 400
ELKVKWVLRP TSIALTWNIP KVNPNCAPVE SYHLFLYYEN SDHLTWKKIA
410 420 430 440 450
EIKALPLPMA CTLSQNLAST KYYFAVQSKD IFGRYGPFCN IKSIPRFSEN

LT
Length:452
Mass (Da):50,975
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i55CC59FCAE6F7422
GO
Isoform 2 (identifier: Q3UL97-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     317-319: GFG → VLT
     320-452: Missing.

Show »
Length:319
Mass (Da):35,848
Checksum:i73DEBA519CD47D0B
GO
Isoform 3 (identifier: Q3UL97-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     288-300: ESPSFTLKSTSKA → GKGCFYIFLSKCM
     301-452: Missing.

Show »
Length:300
Mass (Da):33,899
Checksum:iADAAC83439BBE6D1
GO
Isoform 4 (identifier: Q3UL97-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     204-225: GRKTNLPSTCVEFASESNTDDV → AGFENCGQSPDQFLVPNNSLLT
     226-452: Missing.

Show »
Length:225
Mass (Da):25,487
Checksum:i34F877A522563A6B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8W6K8A0A2R8W6K8_MOUSE
Activating transcription factor 7-i...
Atf7ip2
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti18M → V in AAX99226 (PubMed:16850184).Curated1
Sequence conflicti21S → G in AAX99226 (PubMed:16850184).Curated1
Sequence conflicti97I → V in AAX99226 (PubMed:16850184).Curated1
Sequence conflicti188R → T in BAE24164 (PubMed:16141072).Curated1
Sequence conflicti231 – 233KNS → NFF in BAB30138 (PubMed:16141072).Curated3

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_024044204 – 225GRKTN…NTDDV → AGFENCGQSPDQFLVPNNSL LT in isoform 4. 1 PublicationAdd BLAST22
Alternative sequenceiVSP_024045226 – 452Missing in isoform 4. 1 PublicationAdd BLAST227
Alternative sequenceiVSP_024046288 – 300ESPSF…STSKA → GKGCFYIFLSKCM in isoform 3. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_024047301 – 452Missing in isoform 3. 1 PublicationAdd BLAST152
Alternative sequenceiVSP_024048317 – 319GFG → VLT in isoform 2. 2 Publications3
Alternative sequenceiVSP_024049320 – 452Missing in isoform 2. 2 PublicationsAdd BLAST133

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY903215 mRNA Translation: AAX99226.1
AK016180 mRNA Translation: BAB30138.1
AK077229 mRNA Translation: BAC36698.1
AK139862 mRNA Translation: BAE24164.1
AK145634 mRNA Translation: BAE26553.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49758.1 [Q3UL97-1]
CCDS49759.1 [Q3UL97-3]

NCBI Reference Sequences

More...
RefSeqi
NP_083529.1, NM_029253.1 [Q3UL97-3]
NP_694763.2, NM_153123.2 [Q3UL97-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000044005; ENSMUSP00000036731; ENSMUSG00000039200 [Q3UL97-1]
ENSMUST00000100191; ENSMUSP00000097766; ENSMUSG00000039200 [Q3UL97-4]
ENSMUST00000117220; ENSMUSP00000113573; ENSMUSG00000039200 [Q3UL97-2]
ENSMUST00000119023; ENSMUSP00000113480; ENSMUSG00000039200 [Q3UL97-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
75329

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:75329

UCSC genome browser

More...
UCSCi
uc007ydf.2, mouse [Q3UL97-3]
uc007ydh.2, mouse [Q3UL97-2]
uc007ydi.2, mouse [Q3UL97-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY903215 mRNA Translation: AAX99226.1
AK016180 mRNA Translation: BAB30138.1
AK077229 mRNA Translation: BAC36698.1
AK139862 mRNA Translation: BAE24164.1
AK145634 mRNA Translation: BAE26553.1
CCDSiCCDS49758.1 [Q3UL97-1]
CCDS49759.1 [Q3UL97-3]
RefSeqiNP_083529.1, NM_029253.1 [Q3UL97-3]
NP_694763.2, NM_153123.2 [Q3UL97-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036731

PTM databases

PhosphoSitePlusiQ3UL97

Proteomic databases

PaxDbiQ3UL97
PRIDEiQ3UL97

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
52153, 85 antibodies

Genome annotation databases

EnsembliENSMUST00000044005; ENSMUSP00000036731; ENSMUSG00000039200 [Q3UL97-1]
ENSMUST00000100191; ENSMUSP00000097766; ENSMUSG00000039200 [Q3UL97-4]
ENSMUST00000117220; ENSMUSP00000113573; ENSMUSG00000039200 [Q3UL97-2]
ENSMUST00000119023; ENSMUSP00000113480; ENSMUSG00000039200 [Q3UL97-3]
GeneIDi75329
KEGGimmu:75329
UCSCiuc007ydf.2, mouse [Q3UL97-3]
uc007ydh.2, mouse [Q3UL97-2]
uc007ydi.2, mouse [Q3UL97-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80063
MGIiMGI:1922579, Atf7ip2

Phylogenomic databases

eggNOGiENOG502S2DM, Eukaryota
GeneTreeiENSGT00530000063707
HOGENOMiCLU_025197_0_0_1
InParanoidiQ3UL97
OMAiTCHLSQN
OrthoDBi646436at2759
PhylomeDBiQ3UL97
TreeFamiTF329427

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
75329, 2 hits in 17 CRISPR screens

Protein Ontology

More...
PROi
PR:Q3UL97
RNActiQ3UL97, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000039200, Expressed in spermatocyte and 116 other tissues
ExpressionAtlasiQ3UL97, baseline and differential
GenevisibleiQ3UL97, MM

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR026085, ATF7-int
IPR026089, ATF7-int_2
IPR031870, ATF7IP_BD
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
PANTHERiPTHR23210, PTHR23210, 2 hits
PTHR23210:SF23, PTHR23210:SF23, 2 hits
PfamiView protein in Pfam
PF16788, ATF7IP_BD, 1 hit
PF16794, fn3_4, 1 hit
SUPFAMiSSF49265, SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853, FN3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMCAF2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3UL97
Secondary accession number(s): Q3UT16
, Q4VIF3, Q8BPC5, Q9D4T8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: October 11, 2005
Last modified: February 10, 2021
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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