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Entry version 113 (02 Jun 2021)
Sequence version 3 (27 Jul 2011)
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Protein

Spatacsin

Gene

Spg11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spatacsin
Alternative name(s):
Spastic paraplegia 11 protein homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Spg11
Synonyms:Kiaa1840
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444989, Spg11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell projection, Cytoplasm, Nucleus, Synapse

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002874681 – 2430SpatacsinAdd BLAST2430

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1942PhosphoserineCombined sources1
Modified residuei1943PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q3UHA3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q3UHA3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3UHA3

PeptideAtlas

More...
PeptideAtlasi
Q3UHA3

PRoteomics IDEntifications database

More...
PRIDEi
Q3UHA3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
257060 [Q3UHA3-1]
257061 [Q3UHA3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3UHA3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3UHA3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed at low level. Expressed in embryonic and adult cortical projection neurons.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in all brain areas analyzed from embryonic (18 dpc) and adult mice.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000033396, Expressed in granulocyte and 110 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3UHA3, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with AP5Z1, AP5B1, AP5S1 and ZFYVE26.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
229544, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q3UHA3, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000037543

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3UHA3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1884, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016791

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001081_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3UHA3

Identification of Orthologs from Complete Genome Data

More...
OMAi
SYCEDIY

Database of Orthologous Groups

More...
OrthoDBi
6211at2759

TreeFam database of animal gene trees

More...
TreeFami
TF325171

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028103, Spatacsin
IPR028107, Spatacsin_C_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13650, PTHR13650, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14649, Spatacsin_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q3UHA3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAQPGPGSA ASPGCAGAME RVLPMLLVRI PAEETAQLGP RAQLHRELEA
60 70 80 90 100
LGSLTAAGSL QVLSLAPGSR GGSSCCLPGP FRQFLWEESQ NSTSRDRPKL
110 120 130 140 150
LVAREDYELL VYEFDLRDGR CDAALLHGCC GRTLQKLTED QGVSISFKSL
160 170 180 190 200
RILSFHNNTS LLLINRCLIL RVVFPGKEPG VPVLDCLSLP LPAQAADMII
210 220 230 240 250
DAQLCERFLF VLSTVGLIYI FNTMDGTQVA QVDLALLRED SEQLEPASVS
260 270 280 290 300
SFTSLRVSQD LDVLVLVSSA STAVALNLHL YFRQHPGHLL CEGTLEDLPI
310 320 330 340 350
EGPPGIDEDD LVNSAHNMKL SKVSFQVDRS WRAQLLSLNE SVRGSEPEVS
360 370 380 390 400
CCAPWFQSAL RLESLESADH TPTVPTHVFI PGDVPRGRCA FPQKEHVKSS
410 420 430 440 450
DPGRPWKTMH LSEHEQPTEL TCLSVTGFTA LFTWAVGATS CTIGLWDLET
460 470 480 490 500
QSMQCFSLSQ KCTPVDIGGD QQLCLALTDD GLSLILFGLT QEEFLNRLMI
510 520 530 540 550
HGSASTVDSL CHLNGWGRCS IPIHALEAGI ENRQLDTVDF FLKSKENLLT
560 570 580 590 600
PSSQSPAPDQ QHPFSSHLYL RQVEEMSPAL DLLCSAIRES DSETQSKHFA
610 620 630 640 650
EQLLHLTLSF LNKQIRELCV HTEELDEHFQ KGVAILTSYI NELRTFMIKF
660 670 680 690 700
PWKPGDAIDE SDVNEGVVTV KEDRVWEELS FEEVIADAIL NNRIPEAQTF
710 720 730 740 750
FRISGHSAQR LEELVRIGLD LAFDSLKKNN VEEASRLLRN MGFSVEDELL
760 770 780 790 800
KICFYTTDKN IRDFLVEILK EKECFSEKER RTVDFVHQLE ALYSGHFQEN
810 820 830 840 850
AQTQAFPRYW IKEQDCFKHK SVLDTFLKYD KKDEFHKQDH RIALNWAHRW
860 870 880 890 900
DLQTQECILL RRLSPEEYKA RSPEALWRHL TARHDCSSIS LWMEEFQTQE
910 920 930 940 950
TESPQQSKWP PLSADIIEQG TCCHSHMRNE ILDKLARSGI FLASELEDFE
960 970 980 990 1000
RLLLRLSRIG GVMQDSLPVQ SYKSRAGCDF HSRFILYCLE HGLQHLLYTY
1010 1020 1030 1040 1050
LDYYKLSPGN CPFLEKKELH EAHPWLEFLV QCRQVSSNLT DPKLIFQASL
1060 1070 1080 1090 1100
ANAQILIPTN QASVSSMLLE GHTLLALATT MYAPGGVSQV IQNEDSENCL
1110 1120 1130 1140 1150
KKVDPQLLKV ALTPYPKLKA ALFPQYTAPS ILPSDITLYH LIQSLPPFDP
1160 1170 1180 1190 1200
SRLFVWQSAN TLAIGDTGSQ LPHFSSPDLV SKYAVLERLN YAYYLHHGRP
1210 1220 1230 1240 1250
SFAFGTFLVQ ELIKSKTPKQ LIQQVGKEAY TLGLSSFTNP SVGAACVCFL
1260 1270 1280 1290 1300
ELLGLSSLKL RVDLKMANVI LGSKRRDEDA RSSFIRESLA EKLSKLADGD
1310 1320 1330 1340 1350
RAATEELLVL LEEGVWDSIE QQGFSRLSSE SSSQWALVLQ FCMLHDRKLS
1360 1370 1380 1390 1400
VSYLRECAKA NDWLQFLVHS QLHNYHPAEV ESLLQYFSPV LQSHLKLASE
1410 1420 1430 1440 1450
KLSSGSISRD DSCLQELQKN KGETSNFFEI LHRCSDESTS WSWLLAEAVR
1460 1470 1480 1490 1500
HRAPILSVLA SCVQGASVVS CLCVWIVTSV EDKVAAEAMG HIQISVEDHH
1510 1520 1530 1540 1550
WSLKDLSIIW RTVLTRRKSH TLIRGFQLFI KDSPLLLIME MYELCMFFKN
1560 1570 1580 1590 1600
YEKAKVKLLE FQKSLETLDT VAARVLPIIP ASWMKDQVCF LLKLMPQQCE
1610 1620 1630 1640 1650
TQYELGKLLQ LFVGTEQLFS DGPDVQKLCL LSQVLKDTPI AISPAVISSY
1660 1670 1680 1690 1700
STENFQRECR SILEKLKADG QFAVARRVAE LAALPVDSLL IEQLTQEMQT
1710 1720 1730 1740 1750
LTHTPQWSLK QERLGFWKKC HEIFKKNSIS KRAASSFFSS QAPEVSEHPA
1760 1770 1780 1790 1800
EQGSLEERHL LLTLAGHWLA QEEPVPVEEL EGLEKQIWIC RVAQHTCGGA
1810 1820 1830 1840 1850
EEEAKPSLSQ HKLAAAELSF DSLASELSFS KLAALNTSKY LGLNDLPSKT
1860 1870 1880 1890 1900
TCENRLKHKE QESLNTLIGQ LLDGGCVHEA SRVCQYFRFY SQDLVLVLHC
1910 1920 1930 1940 1950
RALASAEATM EDLHSEIRAL LSSAAQPEDL ESPSVPLRKA HSSSSLDSQS
1960 1970 1980 1990 2000
FVMVPPTDEV AQNLHTLISK CLHGKNYCRQ VLCLYELAKD LGCSYGDVAA
2010 2020 2030 2040 2050
RDSEAMLRAI LASQRPDRCR QAQVFINTQG LEADTVAELV AEEVTRELLT
2060 2070 2080 2090 2100
PSEGTGEKQP FNPAEESQTF LQLTALCQDR TLVGMKLLDK IPSVPHGELS
2110 2120 2130 2140 2150
CTTELLILAH HCFTFTCHME GITRVLQAAR MLTDNHLAPN EEYGLVVRLL
2160 2170 2180 2190 2200
TGIGRYNEMT YIFDLLHQKH YFEVLMRKKL DPTGTLKTAL LDYIKRCRPG
2210 2220 2230 2240 2250
DSEKHNMIAL CFSMCREIGE NHEAAACIQL KLIESQPWEE SLKDGAQLKQ
2260 2270 2280 2290 2300
LLLKALTLML DAAESYAKDS CVRQALHCNR LTKLITLQIH FLNSGQNTML
2310 2320 2330 2340 2350
INLGHQKLMD CIMTLPRFYQ ASIVAEAYDF VPDWAEVLYQ QVILKGDFSY
2360 2370 2380 2390 2400
LEEFKQQKLL RPNIFEDISK KYKQHQPTDR VTENLKKLLS YCEDIYLYYK
2410 2420 2430
LAYEHKFFEI VNMLLKDPQT GCCLKDMLAG
Length:2,430
Mass (Da):273,934
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB8D7CD876C1338BD
GO
Isoform 2 (identifier: Q3UHA3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     479-496: DDGLSLILFGLTQEEFLN → GEQAVSDGRTLRRGVTAL
     497-2430: Missing.

Show »
Length:496
Mass (Da):53,888
Checksum:iC6EF0587324932B8
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH19404 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAC30307 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti579A → S in BAE27954 (PubMed:16141072).Curated1
Sequence conflicti853Q → K in BAC98263 (PubMed:14621295).Curated1
Sequence conflicti929N → H in BAC98263 (PubMed:14621295).Curated1
Sequence conflicti1426N → D in BAC98263 (PubMed:14621295).Curated1
Sequence conflicti1715G → D in BAC98263 (PubMed:14621295).Curated1
Sequence conflicti2192D → G in BAE27954 (PubMed:16141072).Curated1
Sequence conflicti2266Y → C in BAE27954 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025485479 – 496DDGLS…EEFLN → GEQAVSDGRTLRRGVTAL in isoform 2. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_025486497 – 2430Missing in isoform 2. 1 PublicationAdd BLAST1934

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK039286 mRNA Translation: BAC30307.1 Different initiation.
AK049236 mRNA Translation: BAC33628.1
AK049617 mRNA Translation: BAC33842.1
AK083468 mRNA Translation: BAC38926.1
AK147500 mRNA Translation: BAE27954.1
AL845457 Genomic DNA No translation available.
AK129453 mRNA Translation: BAC98263.1
BC019404 mRNA Translation: AAH19404.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS50687.1 [Q3UHA3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_663506.2, NM_145531.2 [Q3UHA3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000036450; ENSMUSP00000037543; ENSMUSG00000033396 [Q3UHA3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
214585

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:214585

UCSC genome browser

More...
UCSCi
uc008mac.2, mouse [Q3UHA3-1]
uc008mad.2, mouse [Q3UHA3-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039286 mRNA Translation: BAC30307.1 Different initiation.
AK049236 mRNA Translation: BAC33628.1
AK049617 mRNA Translation: BAC33842.1
AK083468 mRNA Translation: BAC38926.1
AK147500 mRNA Translation: BAE27954.1
AL845457 Genomic DNA No translation available.
AK129453 mRNA Translation: BAC98263.1
BC019404 mRNA Translation: AAH19404.1 Different initiation.
CCDSiCCDS50687.1 [Q3UHA3-1]
RefSeqiNP_663506.2, NM_145531.2 [Q3UHA3-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi229544, 1 interactor
IntActiQ3UHA3, 1 interactor
STRINGi10090.ENSMUSP00000037543

PTM databases

iPTMnetiQ3UHA3
PhosphoSitePlusiQ3UHA3

Proteomic databases

EPDiQ3UHA3
MaxQBiQ3UHA3
PaxDbiQ3UHA3
PeptideAtlasiQ3UHA3
PRIDEiQ3UHA3
ProteomicsDBi257060 [Q3UHA3-1]
257061 [Q3UHA3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
11596, 88 antibodies

Genome annotation databases

EnsembliENSMUST00000036450; ENSMUSP00000037543; ENSMUSG00000033396 [Q3UHA3-1]
GeneIDi214585
KEGGimmu:214585
UCSCiuc008mac.2, mouse [Q3UHA3-1]
uc008mad.2, mouse [Q3UHA3-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80208
MGIiMGI:2444989, Spg11

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG1884, Eukaryota
GeneTreeiENSGT00390000016791
HOGENOMiCLU_001081_0_0_1
InParanoidiQ3UHA3
OMAiSYCEDIY
OrthoDBi6211at2759
TreeFamiTF325171

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
214585, 0 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Spg11, mouse

Protein Ontology

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PROi
PR:Q3UHA3
RNActiQ3UHA3, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000033396, Expressed in granulocyte and 110 other tissues
GenevisibleiQ3UHA3, MM

Family and domain databases

InterProiView protein in InterPro
IPR028103, Spatacsin
IPR028107, Spatacsin_C_dom
PANTHERiPTHR13650, PTHR13650, 1 hit
PfamiView protein in Pfam
PF14649, Spatacsin_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPTCS_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3UHA3
Secondary accession number(s): A2ARM0
, Q6ZPH3, Q8BHQ1, Q8C7R3, Q8C7U2, Q8CA88, Q8VEA5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 113 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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