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Entry version 138 (29 Sep 2021)
Sequence version 1 (11 Oct 2005)
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Protein

F-box domain-containing protein

Gene

Fbxo41

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathwayARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
F-box domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fbxo41Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1261912, Fbxo41

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000047013

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q3UGY7

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q3UGY7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000047013, Expressed in primary visual cortex and 133 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3UGY7, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini555 – 592F-boxInterPro annotationAdd BLAST38

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni85 – 110DisorderedSequence analysisAdd BLAST26
Regioni163 – 193DisorderedSequence analysisAdd BLAST31
Regioni345 – 540DisorderedSequence analysisAdd BLAST196

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili232 – 301Sequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi168 – 184Pro residuesSequence analysisAdd BLAST17
Compositional biasi388 – 417Polar residuesSequence analysisAdd BLAST30
Compositional biasi439 – 465Polar residuesSequence analysisAdd BLAST27
Compositional biasi471 – 490Basic and acidic residuesSequence analysisAdd BLAST20

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_018140_0_0_1

Identification of Orthologs from Complete Genome Data

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OMAi
HFPCREL

Database of Orthologous Groups

More...
OrthoDBi
236860at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3UGY7

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036047, F-box-like_dom_sf
IPR001810, F-box_dom
IPR032675, LRR_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12937, F-box-like, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81383, SSF81383, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q3UGY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLDLPYRC PRCGEHKRFR SLSSLRAHLE YSHTYETLYI LSKTNSICDG
60 70 80 90 100
AAAAAAAAAA ASGFPLAPEP AALLAVPGAR REVFESTSFQ GKEQATGPSP
110 120 130 140 150
AGPHLLHHHH HHAPLAHFPA DLVPASLPCE ELAEPGLVPA ARYALREIEI
160 170 180 190 200
PLGELFARKS VASSACSTPP PGPGPGPCSG PSSASPASPS PADVAYEEGL
210 220 230 240 250
ARLKIRALEK LEVDRRLERL SEEVEQKIAG QVGRLQAELE RKAAELETAR
260 270 280 290 300
QESARLGREK EELEERASEL SRQVDVSVEL LASLKQDLVH KEQELSRKQQ
310 320 330 340 350
EVVQIDQFLK ETAAREASAK LRLQQFIEEL LERADRAERQ LQVISSSCGS
360 370 380 390 400
TPSASLGRGG GGSASGPGVR GPGRMREHHA GSAVPSTYAV SRHGSSPSTG
410 420 430 440 450
ASSRVPAASQ SSGCYDSDSL ELPRPEEGPS EDSGPGGLGS RAQATNGGSE
460 470 480 490 500
RSQAPRSSGL RRQAIQNWQR RPRRHSTEGE EGDVSDVGSR TTESEAEGPS
510 520 530 540 550
DVPRPGPAVA GPLNSCRLSA RPEGGSGRGR RVERGSPSRS NEVISPEILK
560 570 580 590 600
MRAALFCIFT YLDTRTLLHA AEVCRDWRFV ARHPAVWTRV LLENARVCSK
610 620 630 640 650
FLAMLAQWCT QAHSLTLQNL KPRQRGKKES KEEYARSTRG CLEAGLESLL
660 670 680 690 700
KAAGGNLLIL RISHCPNILT DRSLWLASCY CRALQAVTYR SATDPVGHEV
710 720 730 740 750
IWALGAGCRD IVSLQVAPLH PCQQPTRFSN RCLQMIGRCW PHLRALGVGG
760 770 780 790 800
AGCGVQGLAS LARNCMRLQV LELDHVSEIT QEVAAEVCRE GLKGLEMLVL
810 820 830 840 850
TATPVTPKAL LHFNSICRNL KSIVVQIGIA DYFKEPSSPE AQKLFEDMVT
860 870
KLQALRRRPG FSKILHIKVE GGC
Length:873
Mass (Da):94,331
Last modified:October 11, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2B1BA501527F9700
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK147230 mRNA Translation: BAE27782.1
AK147681 mRNA Translation: BAE28070.1

NCBI Reference Sequences

More...
RefSeqi
NP_001001160.1, NM_001001160.3
NP_001276603.1, NM_001289674.1
NP_001276604.1, NM_001289675.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
330369

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:330369

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK147230 mRNA Translation: BAE27782.1
AK147681 mRNA Translation: BAE28070.1
RefSeqiNP_001001160.1, NM_001001160.3
NP_001276603.1, NM_001289674.1
NP_001276604.1, NM_001289675.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiQ3UGY7

Proteomic databases

PeptideAtlasiQ3UGY7

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
65168, 56 antibodies

The DNASU plasmid repository

More...
DNASUi
330369

Genome annotation databases

GeneIDi330369
KEGGimmu:330369

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
150726
MGIiMGI:1261912, Fbxo41
VEuPathDBiHostDB:ENSMUSG00000047013

Phylogenomic databases

HOGENOMiCLU_018140_0_0_1
OMAiHFPCREL
OrthoDBi236860at2759
PhylomeDBiQ3UGY7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
330369, 1 hit in 61 CRISPR screens

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000047013, Expressed in primary visual cortex and 133 other tissues
ExpressionAtlasiQ3UGY7, baseline and differential

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR036047, F-box-like_dom_sf
IPR001810, F-box_dom
IPR032675, LRR_dom_sf
PfamiView protein in Pfam
PF12937, F-box-like, 1 hit
SUPFAMiSSF81383, SSF81383, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ3UGY7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3UGY7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 29, 2021
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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