UniProtKB - Q3UGH9 (Q3UGH9_MOUSE)
Protein
Submitted name:
Uncharacterized protein
Gene
Pax3
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
GO - Biological processi
- multicellular organism development Source: UniProtKB-KW
Keywordsi
Molecular function | Developmental proteinARBA annotation, DNA-bindingUniRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:Pax3Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:97487, Pax3 |
Subcellular locationi
Nucleus
- Nucleus UniRule annotationARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusUniRule annotationARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 161 | PairedInterPro annotationAdd BLAST | 128 | |
Domaini | 217 – 277 | HomeoboxInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 21 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 165 – 225 | DisorderedSequence analysisAdd BLAST | 61 | |
Regioni | 309 – 351 | DisorderedSequence analysisAdd BLAST | 43 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 165 – 190 | PolyampholyteSequence analysisAdd BLAST | 26 | |
Compositional biasi | 209 – 225 | PolyampholyteSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the paired homeobox family.ARBA annotation
Keywords - Domaini
HomeoboxUniRule annotationARBA annotation, Paired boxARBA annotationFamily and domain databases
CDDi | cd00086, homeodomain, 1 hit cd00131, PAX, 1 hit |
Gene3Di | 1.10.10.10, 2 hits |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR043182, PAIRED_DNA-bd_dom IPR001523, Paired_dom IPR022106, Pax7_C IPR043565, PAX_fam IPR036388, WH-like_DNA-bd_sf |
PANTHERi | PTHR45636, PTHR45636, 1 hit |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF00292, PAX, 1 hit PF12360, Pax7, 1 hit |
PRINTSi | PR00027, PAIREDBOX |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00351, PAX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 2 hits |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit PS00034, PAIRED_1, 1 hit PS51057, PAIRED_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3UGH9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTLAGAVPR MMRPGPGQNY PRSGFPLEVS TPLGQGRVNQ LGGVFINGRP
60 70 80 90 100
LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA
110 120 130 140 150
IGGSKPKQVT TPDVEKKIEE YKRENPGMFS WEIRDKLLKD AVCDRNTVPS
160 170 180 190 200
VSSISRILRS KFGKGEEEEA DLERKEAEES EKKAKHSIDG ILSERASAPQ
210 220 230 240 250
SDEGSDIDSE PDLPLKRKQR RSRTTFTVEQ LEELERAFER THYPDIYTRE
260 270 280 290 300
ELAQRAKLTE ARVQVWFSNR RARWRKQAGA NQLMAFNHLI PGGFPPTAMP
310 320 330 340 350
TLPTYQLSET SYQPTSIPQA VSDPSSTVHR PQPLPPSTVH QSTIPSNADS
360 370 380 390 400
SSAYCLPSTR HGFSSYTDSF VPPSGPSNPM NPTIGNGLSP QVMGLLTNHG
410 420 430 440 450
GVPHQPQTDY ALSPLTGGLE PTTTVSASCS QRLEHMKNVD SLPTSQPYCP
460 470
PTYSTAGYSM DPVTGYQYGQ YGQSKPWTF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK147919 mRNA Translation: BAE28229.1 |
RefSeqi | NP_032807.3, NM_008781.4 |
Genome annotation databases
GeneIDi | 18505 |
KEGGi | mmu:18505 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK147919 mRNA Translation: BAE28229.1 |
RefSeqi | NP_032807.3, NM_008781.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q3UGH9 |
Protocols and materials databases
DNASUi | 18505 |
Genome annotation databases
GeneIDi | 18505 |
KEGGi | mmu:18505 |
Organism-specific databases
CTDi | 5077 |
MGIi | MGI:97487, Pax3 |
Miscellaneous databases
BioGRID-ORCSi | 18505, 2 hits in 53 CRISPR screens |
ChiTaRSi | Pax3, mouse |
SOURCEi | Search... |
Gene expression databases
Genevisiblei | Q3UGH9, MM |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit cd00131, PAX, 1 hit |
Gene3Di | 1.10.10.10, 2 hits |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR043182, PAIRED_DNA-bd_dom IPR001523, Paired_dom IPR022106, Pax7_C IPR043565, PAX_fam IPR036388, WH-like_DNA-bd_sf |
PANTHERi | PTHR45636, PTHR45636, 1 hit |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF00292, PAX, 1 hit PF12360, Pax7, 1 hit |
PRINTSi | PR00027, PAIREDBOX |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00351, PAX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 2 hits |
PROSITEi | View protein in PROSITE PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit PS00034, PAIRED_1, 1 hit PS51057, PAIRED_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3UGH9_MOUSE | |
Accessioni | Q3UGH9Primary (citable) accession number: Q3UGH9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | April 7, 2021 | |
This is version 136 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |