UniProtKB - Q3UFE8 (Q3UFE8_MOUSE)
Protein
Submitted name:
Uncharacterized protein
Gene
Psap
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- beta-galactosidase activity Source: Ensembl
- ganglioside GM1 binding Source: Ensembl
- ganglioside GM2 binding Source: Ensembl
- ganglioside GM3 binding Source: Ensembl
- ganglioside GP1c binding Source: Ensembl
- ganglioside GT1b binding Source: Ensembl
- phospholipid binding Source: Ensembl
- protease binding Source: Ensembl
- protein homodimerization activity Source: Ensembl
GO - Biological processi
- adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Source: UniProtKB-UniRule
- ganglioside GM1 transport to membrane Source: Ensembl
- lysosomal transport Source: Ensembl
- regulation of lipid metabolic process Source: UniProtKB-UniRule
- sphingolipid metabolic process Source: UniProtKB-UniRule
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:PsapImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:97783, Psap |
Subcellular locationi
Extracellular region or secreted
- Secreted ARBA annotation
Endosome
- late endosome Source: Ensembl
Extracellular region or secreted
- extracellular space Source: UniProtKB-UniRule
Lysosome
- lysosome Source: Ensembl
Keywords - Cellular componenti
SecretedARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000004207, Expressed in stroma of bone marrow and 370 other tissues |
Interactioni
GO - Molecular functioni
- protease binding Source: Ensembl
- protein homodimerization activity Source: Ensembl
Family & Domainsi
Keywords - Domaini
RepeatARBA annotation, SignalARBA annotationPhylogenomic databases
OrthoDBi | 865505at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR003119, SAP_A IPR007856, SapB_1 IPR008138, SapB_2 IPR008373, Saposin IPR011001, Saposin-like IPR021165, Saposin_chordata IPR008139, SaposinB_dom |
Pfami | View protein in Pfam PF02199, SapA, 2 hits PF05184, SapB_1, 3 hits PF03489, SapB_2, 4 hits |
PIRSFi | PIRSF002431, Saposin, 1 hit |
PRINTSi | PR01797, SAPOSIN |
SMARTi | View protein in SMART SM00162, SAPA, 2 hits SM00741, SapB, 4 hits |
SUPFAMi | SSF47862, SSF47862, 3 hits |
PROSITEi | View protein in PROSITE PS51110, SAP_A, 2 hits PS50015, SAP_B, 4 hits |
i Sequence
Sequence statusi: Complete.
Q3UFE8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MYALALFASL LATALTSPVQ DPKTCSGGSA VLCRDVKTAV DCGAVKHCQQ
60 70 80 90 100
MVWSKPTAKS LPCDICKTVV TEAGNLLKDN ATQEEILHYL EKTCEWIHDS
110 120 130 140 150
SLSASCKEVV DSYLPVILDM IKGEMSNPGE VCSALNLCQS LQEYLAEQNQ
160 170 180 190 200
KQLESNKIPE VDMARVVAPF MSNIPLLLYP QDHPRSQPQP KANEDVCQDC
210 220 230 240 250
MKLVSDVQTA VKTNSSFIQG FVDHVKEDCD RLGPGVSDIC KNYVDQYSEV
260 270 280 290 300
CVQMLMHMQD QQPKEICVLA GFCNEVKRVP MKTLVPATET IKNILPALEM
310 320 330 340 350
MDPYEQNLVQ AHNVILCQTC QFVMNKFSEL IVNNATEELL VKGLSNACAL
360 370 380 390 400
LPDPARTKCQ EVVGTFGPSL LDIFIHEVNP SSLCGVIGLC AARPELVEAL
410 420 430 440 450
EQPAPAIVSA LLKEPTPPKQ PAQPKQSALP AHVPPQKNGG FCEVCKKLVL
460 470 480 490 500
YLEHNLEKNS TKEEILAALE KGCSFLPDPY QKQCDDFVAE YEPLLLEILV
510 520 530 540 550
EVMDPGFVCS KIGVCPSAYK LLLGTEKCVW GPSYWCQNME TAARCNAVDH
CKRHVWN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK148545 mRNA Translation: BAE28613.1 |
RefSeqi | NP_035309.3, NM_011179.3 |
Genome annotation databases
GeneIDi | 19156 |
KEGGi | mmu:19156 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK148545 mRNA Translation: BAE28613.1 |
RefSeqi | NP_035309.3, NM_011179.3 |
3D structure databases
SMRi | Q3UFE8 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 1388, 437 antibodies |
Genome annotation databases
GeneIDi | 19156 |
KEGGi | mmu:19156 |
Organism-specific databases
CTDi | 5660 |
MGIi | MGI:97783, Psap |
Phylogenomic databases
OrthoDBi | 865505at2759 |
Miscellaneous databases
BioGRID-ORCSi | 19156, 0 hits in 17 CRISPR screens |
ChiTaRSi | Psap, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000004207, Expressed in stroma of bone marrow and 370 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR003119, SAP_A IPR007856, SapB_1 IPR008138, SapB_2 IPR008373, Saposin IPR011001, Saposin-like IPR021165, Saposin_chordata IPR008139, SaposinB_dom |
Pfami | View protein in Pfam PF02199, SapA, 2 hits PF05184, SapB_1, 3 hits PF03489, SapB_2, 4 hits |
PIRSFi | PIRSF002431, Saposin, 1 hit |
PRINTSi | PR01797, SAPOSIN |
SMARTi | View protein in SMART SM00162, SAPA, 2 hits SM00741, SapB, 4 hits |
SUPFAMi | SSF47862, SSF47862, 3 hits |
PROSITEi | View protein in PROSITE PS51110, SAP_A, 2 hits PS50015, SAP_B, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q3UFE8_MOUSE | |
Accessioni | Q3UFE8Primary (citable) accession number: Q3UFE8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 11, 2005 |
Last sequence update: | October 11, 2005 | |
Last modified: | December 2, 2020 | |
This is version 121 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |