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Protein
Submitted name:

Thyroxine-binding globulin

Gene

Serpina7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Thyroxine-binding globulinImported
Gene namesi
Name:Serpina7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:3041197 Serpina7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501509747625 – 426Sequence analysisAdd BLAST402

Expressioni

Gene expression databases

BgeeiENSMUSG00000031271 Expressed in 33 organ(s), highest expression level in liver

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 423SERPINInterPro annotationAdd BLAST362

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
HOGENOMiHOG000238521
HOVERGENiHBG005957
KOiK20734
OMAiELQMGNA
OrthoDBiEOG091G0ION
TreeFamiTF343201

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q3UEL9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCYHLHSRMS VFFYLFVLVF GLQATIHCAP HNSSEGKVTT CHLPQQNATL
60 70 80 90 100
YKMPSINADF AFSLYRRLSV ENPDLNIFFS PVSISVALAM LSFGSGSSTQ
110 120 130 140 150
TQILEVLGFN LTDTPVTELQ QGFQHLICSL NFPKNELELQ MGNAVFIGQQ
160 170 180 190 200
LKPLAKFLDD VKTLYETEVF STDFSNVSAA QHKINSYVEK QTKGKIVGLI
210 220 230 240 250
QGLKLNIIMI LVNYIHFRAQ WANPFRVSKT EESSNFSVDK STTVQVPMMH
260 270 280 290 300
QLEQYYHYVD MELNCTVLQM DYSENALALF VLPKEGHMEW VEAAMSSKTL
310 320 330 340 350
KKWNYLLQKG WVELFVPKFS ISATYDLGST LQKMGMRDAF AESADFPGIT
360 370 380 390 400
EDSGLKLSYA FHKAVLHIGE EGTKEGASPE VGSLDQQEVP PLHPVIRLDR
410 420
AFLLMILEKR TRSVLFLGKL VNPTKQ
Length:426
Mass (Da):48,080
Last modified:October 11, 2005 - v1
Checksum:iD073BE00A6148E60
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P61939THBG_MOUSE
Thyroxine-binding globulin
Serpina7 Tbg
418Annotation score:
B1AW62B1AW62_MOUSE
Thyroxine-binding globulin
Serpina7
72Annotation score:
Q8BII9Q8BII9_MOUSE
Thyroxine-binding globulin
Serpina7
287Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732419 Genomic DNA No translation available.
AK149459 mRNA Translation: BAE28892.1
RefSeqiNP_808588.3, NM_177920.5
UniGeneiMm.211704

Genome annotation databases

EnsembliENSMUST00000033626; ENSMUSP00000033626; ENSMUSG00000031271
GeneIDi331535
KEGGimmu:331535
UCSCiuc009ukb.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732419 Genomic DNA No translation available.
AK149459 mRNA Translation: BAE28892.1
RefSeqiNP_808588.3, NM_177920.5
UniGeneiMm.211704

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000033626; ENSMUSP00000033626; ENSMUSG00000031271
GeneIDi331535
KEGGimmu:331535
UCSCiuc009ukb.2 mouse

Organism-specific databases

CTDi6906
MGIiMGI:3041197 Serpina7

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
HOGENOMiHOG000238521
HOVERGENiHBG005957
KOiK20734
OMAiELQMGNA
OrthoDBiEOG091G0ION
TreeFamiTF343201

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031271 Expressed in 33 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UEL9_MOUSE
AccessioniPrimary (citable) accession number: Q3UEL9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 7, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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