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Protein

Heparan-alpha-glucosaminide N-acetyltransferase

Gene

Hgsnat

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase.1 Publication

Miscellaneous

A signal sequence is predicted but has been shown not to be cleaved in the reticulum endoplasmic.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei290By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.1.78 3474

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-2024096 HS-GAG degradation
R-MMU-6798695 Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Heparan-alpha-glucosaminide N-acetyltransferase (EC:2.3.1.78)
Alternative name(s):
Transmembrane protein 76
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Hgsnat
Synonyms:D8Ertd354e, Tmem76
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1196297 Hgsnat

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 185Lumenal, vesicleSequence analysisAdd BLAST185
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei186 – 206HelicalSequence analysisAdd BLAST21
Topological domaini207 – 268CytoplasmicSequence analysisAdd BLAST62
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Topological domaini290 – 295Lumenal, vesicleSequence analysis6
Transmembranei296 – 316HelicalSequence analysisAdd BLAST21
Topological domaini317 – 338CytoplasmicSequence analysisAdd BLAST22
Transmembranei339 – 359HelicalSequence analysisAdd BLAST21
Topological domaini360 – 367Lumenal, vesicleSequence analysis8
Transmembranei368 – 388HelicalSequence analysisAdd BLAST21
Topological domaini389 – 413CytoplasmicSequence analysisAdd BLAST25
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Topological domaini435 – 493Lumenal, vesicleSequence analysisAdd BLAST59
Transmembranei494 – 514HelicalSequence analysisAdd BLAST21
Topological domaini515 – 522CytoplasmicSequence analysis8
Transmembranei523 – 543HelicalSequence analysisAdd BLAST21
Topological domaini544 – 557Lumenal, vesicleSequence analysisAdd BLAST14
Transmembranei558 – 578HelicalSequence analysisAdd BLAST21
Topological domaini579 – 585CytoplasmicSequence analysis7
Transmembranei586 – 606HelicalSequence analysisAdd BLAST21
Topological domaini607 – 627Lumenal, vesicleSequence analysisAdd BLAST21
Transmembranei628 – 648HelicalSequence analysisAdd BLAST21
Topological domaini649 – 656CytoplasmicSequence analysis8

Keywords - Cellular componenti

Lysosome, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002731541 – 656Heparan-alpha-glucosaminide N-acetyltransferaseAdd BLAST656

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi137N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi146 ↔ 455By similarity
Glycosylationi157N-linked (GlcNAc...) asparagine1 Publication1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei238PhosphoserineBy similarity1
Modified residuei240PhosphoserineBy similarity1
Modified residuei249PhosphotyrosineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Undergoes intralysosomal proteolytic cleavage; occurs within the end of the first and/or the beginning of the second luminal domain and is essential for the activation of the enzyme.By similarity
Glycosylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q3UDW8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3UDW8

PeptideAtlas

More...
PeptideAtlasi
Q3UDW8

PRoteomics IDEntifications database

More...
PRIDEi
Q3UDW8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3UDW8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3UDW8

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q3UDW8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the retina.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in the developing eye as early as embryonic day 14 (E14), with equal high expression levels after birth (postnatal day 0 (P0) and postnatal day 30 (P30)).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000037260 Expressed in 291 organ(s), highest expression level in stroma of bone marrow

CleanEx database of gene expression profiles

More...
CleanExi
MM_HGSNAT

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3UDW8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3UDW8 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homooligomer. Homooligomerization is necessary for enzyme activity (By similarity).By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000040356

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q3UDW8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni641 – 656Lysosomal targeting regionBy similarityAdd BLAST16

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4683 Eukaryota
COG4299 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001491

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006803

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG081599

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3UDW8

KEGG Orthology (KO)

More...
KOi
K10532

Identification of Orthologs from Complete Genome Data

More...
OMAi
KHSSWNG

Database of Orthologous Groups

More...
OrthoDBi
EOG091G042R

TreeFam database of animal gene trees

More...
TreeFami
TF324790

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012429 DUF1624
IPR040208 HGSNAT

The PANTHER Classification System

More...
PANTHERi
PTHR31061:SF19 PTHR31061:SF19, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07786 DUF1624, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative initiation. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q3UDW8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTGGSSSRRR RAEERSSAAG TERNSRREAV GGMGAGPALA ALLLAGSVLS
60 70 80 90 100
ATLLAPGRRA EPDLDEKRNV ELKMDQALLL IHNELLGTSL TVYWKSDDCY
110 120 130 140 150
QCTFQPLANV SHGGKPAKPS VAPVSVSTQH GSILQVNSTS EERAACRLEY
160 170 180 190 200
KFGEFGNYSL LVQHASSGAN KIACDIIVNE NPVDSNLPVS IAFLVGLALI
210 220 230 240 250
VAVSLLRLLL SLDDVNNWIS KTIASRETDR LINSELGSPS RADPLSADYQ
260 270 280 290 300
PETRRSSANR LRCVDTFRGL ALVLMVFVNY GGGKYWYFKH SSWNGLTVAD
310 320 330 340 350
LVFPWFVFIM GTSIFLSMTS ILQRGCSKLK LLGKIVWRSF LLICIGVIIV
360 370 380 390 400
NPNYCLGPLS WDKVRIPGVL QRLGVTYFVV AVLEFFFWKP VPDSCTLESS
410 420 430 440 450
CFSLRDITSS WPQWLTILTL ESIWLALTFF LPVPGCPTGY LGPGGIGDLG
460 470 480 490 500
KYPHCTGGAA GYIDRLLLGD NHLYQHPSST VLYHTEVAYD PEGVLGTINS
510 520 530 540 550
IVMAFLGVQA GKILVYYKDQ TKAILTRFAA WCCILGLISI VLTKVSANEG
560 570 580 590 600
FIPINKNLWS ISYVTTLSCF AFFILLILYP VVDVKGLWTG TPFFYPGMNS
610 620 630 640 650
ILVYVGHEVL ENYFPFQWKL ADEQSHKEHL IQNIVATALW VLIAYVLYKK

KLFWKI
Length:656
Mass (Da):72,504
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8FAE5EBECED5CCE3
GO
Isoform 2 (identifier: Q3UDW8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-32: Missing.

Show »
Length:624
Mass (Da):69,100
Checksum:i5272EA184EB5BDA4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GRV1A0A1B0GRV1_MOUSE
Heparan-alpha-glucosaminide N-acety...
Hgsnat
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH24084 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC29006 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAE31601 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAE35261 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAE35603 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti23R → H in AAH24084 (PubMed:15489334).Curated1
Sequence conflicti24N → S in AAH24084 (PubMed:15489334).Curated1
Sequence conflicti222T → A in AAH24084 (PubMed:15489334).Curated1
Sequence conflicti242A → G in BAE35261 (PubMed:16141072).Curated1
Sequence conflicti329L → F in BAE29143 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0405051 – 32Missing in isoform 2. CuratedAdd BLAST32

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK035264 mRNA Translation: BAC29006.1 Different initiation.
AK149883 mRNA Translation: BAE29143.1
AK152926 mRNA Translation: BAE31601.1 Different initiation.
AK159649 mRNA Translation: BAE35261.1 Different initiation.
AK160068 mRNA Translation: BAE35603.1 Different initiation.
AC093366 Genomic DNA No translation available.
BC024084 mRNA Translation: AAH24084.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40309.1 [Q3UDW8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_084160.1, NM_029884.1 [Q3UDW8-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.235663
Mm.28326
Mm.285785

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000037609; ENSMUSP00000040356; ENSMUSG00000037260 [Q3UDW8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
52120

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:52120

UCSC genome browser

More...
UCSCi
uc009lhg.1 mouse [Q3UDW8-1]

Keywords - Coding sequence diversityi

Alternative initiation

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK035264 mRNA Translation: BAC29006.1 Different initiation.
AK149883 mRNA Translation: BAE29143.1
AK152926 mRNA Translation: BAE31601.1 Different initiation.
AK159649 mRNA Translation: BAE35261.1 Different initiation.
AK160068 mRNA Translation: BAE35603.1 Different initiation.
AC093366 Genomic DNA No translation available.
BC024084 mRNA Translation: AAH24084.1 Different initiation.
CCDSiCCDS40309.1 [Q3UDW8-1]
RefSeqiNP_084160.1, NM_029884.1 [Q3UDW8-1]
UniGeneiMm.235663
Mm.28326
Mm.285785

3D structure databases

ProteinModelPortaliQ3UDW8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040356

PTM databases

iPTMnetiQ3UDW8
PhosphoSitePlusiQ3UDW8
SwissPalmiQ3UDW8

Proteomic databases

MaxQBiQ3UDW8
PaxDbiQ3UDW8
PeptideAtlasiQ3UDW8
PRIDEiQ3UDW8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000037609; ENSMUSP00000040356; ENSMUSG00000037260 [Q3UDW8-1]
GeneIDi52120
KEGGimmu:52120
UCSCiuc009lhg.1 mouse [Q3UDW8-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
138050
MGIiMGI:1196297 Hgsnat

Phylogenomic databases

eggNOGiKOG4683 Eukaryota
COG4299 LUCA
GeneTreeiENSGT00390000001491
HOGENOMiHOG000006803
HOVERGENiHBG081599
InParanoidiQ3UDW8
KOiK10532
OMAiKHSSWNG
OrthoDBiEOG091G042R
TreeFamiTF324790

Enzyme and pathway databases

BRENDAi2.3.1.78 3474
ReactomeiR-MMU-2024096 HS-GAG degradation
R-MMU-6798695 Neutrophil degranulation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Hgsnat mouse

Protein Ontology

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PROi
PR:Q3UDW8

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000037260 Expressed in 291 organ(s), highest expression level in stroma of bone marrow
CleanExiMM_HGSNAT
ExpressionAtlasiQ3UDW8 baseline and differential
GenevisibleiQ3UDW8 MM

Family and domain databases

InterProiView protein in InterPro
IPR012429 DUF1624
IPR040208 HGSNAT
PANTHERiPTHR31061:SF19 PTHR31061:SF19, 1 hit
PfamiView protein in Pfam
PF07786 DUF1624, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHGNAT_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3UDW8
Secondary accession number(s): E9QNP9
, Q3TWK5, Q8CBU7, Q8CIE1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: July 27, 2011
Last modified: December 5, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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