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Entry version 106 (02 Jun 2021)
Sequence version 2 (06 Feb 2007)
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Protein

Transforming growth factor beta regulator 1

Gene

Tbrg1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transforming growth factor beta regulator 1
Alternative name(s):
Nuclear interactor of ARF and Mdm2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tbrg1
Synonyms:Niam
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1100877, Tbrg1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Tumor suppressor

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002742192 – 406Transforming growth factor beta regulator 1Add BLAST405

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei13PhosphothreonineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Ubiquitinated; mediated by MDM2 and leading to its subsequent proteasomal degradation.By similarity

Keywords - PTMi

Acetylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q3UB74

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q3UB74

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q3UB74

PeptideAtlas

More...
PeptideAtlasi
Q3UB74

PRoteomics IDEntifications database

More...
PRIDEi
Q3UB74

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
263013

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q3UB74

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q3UB74

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced in cells undergoing arrest in response to DNA damage and TGFB1 treatment.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000011114, Expressed in placenta and 327 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q3UB74, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q3UB74, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CDKN2A and MDM2.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
203980, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q3UB74, 1 interactor

Molecular INTeraction database

More...
MINTi
Q3UB74

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000112600

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q3UB74, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q3UB74

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini177 – 236FYR N-terminalPROSITE-ProRule annotationAdd BLAST60
Domaini237 – 316FYR C-terminalPROSITE-ProRule annotationAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28DisorderedSequence analysisAdd BLAST28
Regioni109 – 144DisorderedSequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi126 – 144Basic and acidic residuesSequence analysisAdd BLAST19

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TBRG1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4443, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013374

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_037126_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q3UB74

Identification of Orthologs from Complete Genome Data

More...
OMAi
WIYPVGY

Database of Orthologous Groups

More...
OrthoDBi
1397649at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q3UB74

TreeFam database of animal gene trees

More...
TreeFami
TF324736

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003889, FYrich_C
IPR003888, FYrich_N
IPR040092, TBRG1

The PANTHER Classification System

More...
PANTHERi
PTHR22715, PTHR22715, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05965, FYRC, 1 hit
PF05964, FYRN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00542, FYRC, 1 hit
SM00541, FYRN, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51543, FYRC, 1 hit
PS51542, FYRN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q3UB74-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVLSGLASE PRTPLSSKAR MKRLPRKSQN EKYRLKYLRL RRAAKATVFE
60 70 80 90 100
NASICDEIAR LEEKFLKAKE ERRYLLKKLL QIHALTEGEP QAAAPSHSSS
110 120 130 140 150
LPLPYGVTSS VGTMQGAGPS TGAEEPFAKK SKKEKKEKGK ENSKLEVLKK
160 170 180 190 200
TSKKKKMEGG ARKLVRPIAL DPSGQPVFPI GLGGLTVYSL GEIITNRPGF
210 220 230 240 250
HDENAIYPVG YCSTRVYASM KCPDQKCLYT CQIKDGGVQP QFEIVPEDDP
260 270 280 290 300
QNTIVGSSAD ACYEELLRAI SATTGKLMPN PLSCGADFFG FSHPTIHNLI
310 320 330 340 350
QSCPEAQNCV NYQWVKFDAC KPRKGQLSQE LPENDATMSL EAFQTQTFDD
360 370 380 390 400
DHDDSILPGS LDLPELQHEA FVSSYQPEFL THEPLVDTDL QHLKSPSQCS

PIQSSD
Length:406
Mass (Da):44,881
Last modified:February 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEBF4AED368200625
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1L1STM2A0A1L1STM2_MOUSE
Transforming growth factor beta reg...
Tbrg1
201Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH21331 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH40813 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH43022 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH65795 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti32K → M in BAE29651 (PubMed:16141072).Curated1
Sequence conflicti180I → T in BAE30090 (PubMed:16141072).Curated1
Sequence conflicti188Y → C in BAE30090 (PubMed:16141072).Curated1
Sequence conflicti207Y → N in BAE29651 (PubMed:16141072).Curated1
Sequence conflicti228L → P in BAE30090 (PubMed:16141072).Curated1
Sequence conflicti271S → G in BAE38845 (PubMed:16141072).Curated1
Sequence conflicti304P → L in AAH43022 (PubMed:15489334).Curated1
Sequence conflicti382H → Y in BAE38845 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ144541 mRNA Translation: AAZ76015.1
AK150549 mRNA Translation: BAE29651.1
AK151075 mRNA Translation: BAE30090.1
AK151457 mRNA Translation: BAE30416.1
AK151209 mRNA Translation: BAE30204.1
AK166547 mRNA Translation: BAE38845.1
BC021331 mRNA Translation: AAH21331.1 Different initiation.
BC040813 mRNA Translation: AAH40813.3 Different initiation.
BC043022 mRNA Translation: AAH43022.3 Different initiation.
BC065795 mRNA Translation: AAH65795.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS52771.1

NCBI Reference Sequences

More...
RefSeqi
NP_079565.2, NM_025289.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000117654; ENSMUSP00000112600; ENSMUSG00000011114

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
21376

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:21376

UCSC genome browser

More...
UCSCi
uc009ovh.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ144541 mRNA Translation: AAZ76015.1
AK150549 mRNA Translation: BAE29651.1
AK151075 mRNA Translation: BAE30090.1
AK151457 mRNA Translation: BAE30416.1
AK151209 mRNA Translation: BAE30204.1
AK166547 mRNA Translation: BAE38845.1
BC021331 mRNA Translation: AAH21331.1 Different initiation.
BC040813 mRNA Translation: AAH40813.3 Different initiation.
BC043022 mRNA Translation: AAH43022.3 Different initiation.
BC065795 mRNA Translation: AAH65795.1 Different initiation.
CCDSiCCDS52771.1
RefSeqiNP_079565.2, NM_025289.3

3D structure databases

SMRiQ3UB74
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi203980, 6 interactors
IntActiQ3UB74, 1 interactor
MINTiQ3UB74
STRINGi10090.ENSMUSP00000112600

PTM databases

iPTMnetiQ3UB74
PhosphoSitePlusiQ3UB74

Proteomic databases

EPDiQ3UB74
MaxQBiQ3UB74
PaxDbiQ3UB74
PeptideAtlasiQ3UB74
PRIDEiQ3UB74
ProteomicsDBi263013

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
45986, 142 antibodies

The DNASU plasmid repository

More...
DNASUi
21376

Genome annotation databases

EnsembliENSMUST00000117654; ENSMUSP00000112600; ENSMUSG00000011114
GeneIDi21376
KEGGimmu:21376
UCSCiuc009ovh.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84897
MGIiMGI:1100877, Tbrg1

Phylogenomic databases

eggNOGiKOG4443, Eukaryota
GeneTreeiENSGT00390000013374
HOGENOMiCLU_037126_0_0_1
InParanoidiQ3UB74
OMAiWIYPVGY
OrthoDBi1397649at2759
PhylomeDBiQ3UB74
TreeFamiTF324736

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
21376, 3 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tbrg1, mouse

Protein Ontology

More...
PROi
PR:Q3UB74
RNActiQ3UB74, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000011114, Expressed in placenta and 327 other tissues
ExpressionAtlasiQ3UB74, baseline and differential
GenevisibleiQ3UB74, MM

Family and domain databases

InterProiView protein in InterPro
IPR003889, FYrich_C
IPR003888, FYrich_N
IPR040092, TBRG1
PANTHERiPTHR22715, PTHR22715, 1 hit
PfamiView protein in Pfam
PF05965, FYRC, 1 hit
PF05964, FYRN, 1 hit
SMARTiView protein in SMART
SM00542, FYRC, 1 hit
SM00541, FYRN, 1 hit
PROSITEiView protein in PROSITE
PS51543, FYRC, 1 hit
PS51542, FYRN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTBRG1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q3UB74
Secondary accession number(s): Q3TLE7
, Q3UCG2, Q3YBR3, Q6P067, Q80XA1, Q8CGC5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 2, 2021
This is version 106 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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